List of MPs who lost their seat in the 2010 United Kingdom general election
# List of MPs who lost their seat in the 2010 United Kingdom general election

This is a list of MPs who lost their seat at the 2010 United Kingdom general election. In total, 74 MPs lost their seats.

## Members of Parliament who lost their seats

| Party | Name | Constituency | Last office held whilst in power | Year elected | Defeated by | Party |
| - | - | - | - | - | - | - |
| Labour Party | Judy Mallaber | Amber Valley | | 1997 | Nigel Mills | Conservative Party |
| Labour Party | Angela Smith | Basildon, contesting South Basildon and East Thurrock | Minister of State for Third Sector (2009-2010) | 1997 | Stephen Metcalfe | Conservative Party |
| Labour Party | Martin Linton | Battersea | | 1997 | Jane Ellison | Conservative Party |
| Labour Party | Patrick Hall | Bedford | | 1997 | Richard Fuller | Conservative Party |
| Labour Party | Terry Rooney | Bradford North, contesting Bradford East | | 1990 | David Ward | Liberal Democrats |
| Labour Party | Ann Keen | Brentford and Isleworth | Parliamentary Under-Secretary of State for Health Services (2007-2010) | 1997 | Mary Macleod | Conservative Party |
| Labour Party | Dawn Butler | Brent South, contesting Brent Central | Minister for Young Citizens and Youth Engagement (2009-2010) | 2005 | Sarah Teather MP | Liberal Democrats |
| Labour Party | Ian Cawsey | Brigg and Goole | | 1997 | Andrew Percy | Conservative Party |
| Labour Party | Nick Palmer | Broxtowe | | 1997 | Anna Soubry | Conservative Party |
| Labour Party | Julie Morgan | Cardiff North | | 1997 | Jonathan Evans | Conservative Party |
| Labour Party | Nick Ainger | Carmarthen West and South Pembrokeshire | Parliamentary Under-Secretary of State for the Wales Office (2005-2007) | 1992 | Simon Hart | Conservative Party |
| Labour Party | Jonathan Shaw | Chatham and Aylesford | Parliamentary Under-Secretary of State for the Department for Work and Pensions and Minister for Disabled People (2007-2010) | 1997 | Tracey Crouch | Conservative Party |
| Labour Party | Christine Russell | City of Chester | | 1997 | Stephen Mosley | Conservative Party |
| Labour Party | Shona McIsaac | Cleethorpes | | 1997 | Martin Vickers | Conservative Party |
| Labour Party | Phil Hope | Corby | Minister of State for Health (2008-2010) | 1997 | Louise Mensch | Conservative Party |
| Labour Party | Shahid Malik | Dewsbury | Parliamentary Under-Secretary of State for the Department for Communities and Local Government (2009-2010) | 2005 | Simon Reevell | Conservative Party |
| Labour Party | Gwyn Prosser | Dover | | 1997 | Charlie Elphicke | Conservative Party |
| Labour Party | Joan Ryan | Enfield North | Parliamentary Under Secretary of State for Nationality, Citizenship and Immigration (2006-2007) | 1997 | Nick de Bois | Conservative Party |
| Labour Party | Paul Clark | Gillingham, contesting Gillingham and Rainham | Parliamentary Under-Secretary of State for the Department for Transport (2008-2010) | 1997 | Rehman Chishti | Conservative Party |
| Labour Party | Parmjit Dhanda | Gloucester | Parliamentary Under-Secretary of State, Department of Communities and Local Government (2006-2007) | 2001 | Richard Graham | Conservative Party |
| Labour Party | Tony Wright | Great Yarmouth | | 1997 | Brandon Lewis | Conservative Party |
| Labour Party | Bill Rammell | Harlow | Minister of State for the Armed Forces (2009-2010) | 1997 | Robert Halfon | Conservative Party |
| Labour Party | Tony McNulty | Harrow East | Minister of State for Employment and Welfare Reform (2008-2009) | 1997 | Bob Blackman | Conservative Party |
| Labour Party | Michael (Jabez) Foster | Hastings and Rye | Parliamentary Under-Secretary of State for the Home Office (2009-2010) | 1997 | Amber Rudd | Conservative Party |
| Labour Party | Andrew Dismore | Hendon | | 1997 | Matthew Offord | Conservative Party |
| Labour Party | Celia Barlow | Hove | Parliamentary Under-Secretary of State for the Department for Business, Enterprise and Regulatory Reform (2008-2010) | 2005 | Mike Weatherley | Conservative Party |
| Labour Party | Chris Mole | Ipswich | Parliamentary Under-Secretary of State for the Department for Transport (2009-2010) | 2001 | Ben Gummer | Conservative Party |
| Labour Party | Gillian Merron | Lincoln | Minister of State for Public Health (2009-2010) | 1997 | Karl McCartney | Conservative Party |
| Labour Party | Andy Reed | Loughborough | | 1997 | Nicky Morgan | Conservative Party |
| Labour Party | Roger Berry | Kingswood | | 1992 | Chris Skidmore | Conservative Party |
| Labour Party | Phyllis Starkey | Milton Keynes South West, contesting Milton Keynes South | Chair of the Communities and Local Government Select Committee (2005-2010) | 1997 | Iain Stewart | Conservative Party |
| Labour Party | Geraldine Smith | Morecambe and Lunesdale | | 1997 | David Morris | Conservative Party |
| Labour Party | Sally Keeble | Northampton North | Parliamentary Under Secretary of State for the Department for International Development (2003-2005) | 1997 | Michael Ellis | Conservative Party |
| Labour Party | Mike O'Brien | North Warwickshire | Minister of State for Health Services (2009-2010) | 1992 | Dan Byles | Conservative Party |
| Labour Party | Charles Clarke | Norwich South | Home Secretary (2004–06) | 1997 | Simon Wright | Liberal Democrats |
| Labour Party | Gordon Prentice | Pendle | | 1992 | Andrew Stephenson | Conservative Party |
| Labour Party | Linda Gilroy | Plymouth Sutton, contesting Plymouth Sutton and Devonport | | 1997 | Oliver Colvile | Conservative Party |
| Labour Party | Sarah McCarthy-Fry | Portsmouth North | Exchequer Secretary to the Treasury (2009-2010) | 2005 | Penny Mordaunt | Conservative Party |
| Labour Party | Vera Baird | Redcar | Solicitor General for England and Wales (2007-2010) | 2001 | Ian Swales | Liberal Democrats |
| Labour Party | Jacqui Smith | Redditch | Home Secretary (2007–09) | 1997 | Karen Lumley | Conservative Party |
| Labour Party | Janet Anderson | Rossendale and Darwen | Vice-Chamberlain of the Household (1997-1998) | 1992 | Jake Berry | Conservative Party |
| Labour Party | Jim Knight | South Dorset | Minister of State for Employment and Welfare Reform (2009-2010) | 2001 | Richard Drax | Conservative Party |
| Labour Party | David Borrow | South Ribble | | 1997 | Lorraine Fullbrook | Conservative Party |
| Labour Party | Stephen Ladyman | South Thanet | | 1997 | Laura Sandys | Conservative Party |
| Labour Party | David Kidney | Stafford | Parliamentary Under Secretary of State for the Department for Energy and Climate Change (2009-2010) | 1997 | Jeremy Lefroy | Conservative Party |
| Labour Party | Charlotte Atkins | Staffordshire Moorlands | Parliamentary Under-Secretary of State for the Department for Transport (2004-2005) | 1997 | Karen Bradley | Conservative Party |
| Labour Party | Dari Taylor | Stockton South | | 1997 | James Wharton | Conservative Party' |
| Labour Party | Lynda Waltho | Stourbridge | | 2005 | Margot James | Conservative Party |
| Labour Party | David Drew | Stroud | | 1997 | Neil Carmichael | Conservative Party |
| Labour Party | Anne Snelgrove | Swindon South | | 2005 | Robert Buckland | Conservative Party |
| Labour Party | Brian Jenkins | Tamworth | | 1996 | Christopher Pincher | Conservative Party |
| Labour Party | Dan Norris | Wansdyke, contesting North East Somerset | Parliamentary Under Secretary of State for the Department for the Environment, Food and Rural Affairs (2009-2010) | 1997 | Jacob Rees-Mogg | Conservative Party |
| Labour Party | James Plaskitt | Warwick and Leamington | Parliamentary Under-Secretary of State for the Department for Work and Pensions (2005-2008) | 1997 | Chris White | Conservative Party |
| Labour Party | Claire Ward | Watford | Parliamentary Under Secretary of State for Justice (2009-2010) | 1997 | Richard Harrington | Conservative Party |
| Labour Party | Bob Blizzard | Waveney | Lord Commissioner of HM Treasury (2008-2010) | 1997 | Peter Aldous | Conservative Party |
| Labour Party | Rob Marris | Wolverhampton South West | | 2001 | Paul Uppal | Conservative Party |
| Labour Party | Michael Foster | Worcester | Parliamentary Under-Secretary of State for the Department for International Development (2008-2010) | 1997 | Robin Walker | Conservative Party |
| Liberal Democrats | Paul Holmes | Chesterfield | Justice Spokesman and Chairman of the Liberal Democrats (2005-2010) | 2001 | Toby Perkins | Labour Party |
| Liberal Democrats | Willie Rennie | Dunfermline and West Fife | Chair of the Lib Dem Campaigns Team (2008-2010) | 2006 | Thomas Docherty | Labour Party |
| Liberal Democrats | Julia Goldsworthy | Falmouth and Camborne, contesting Camborne and Redruth | Communities and Local Government Spokesman (2007-2010) | 2005 | George Eustice | Conservative Party |
| Liberal Democrats | Lembit Öpik | Montgomeryshire | Housing Spokesman (2008-2010) | 1997 | Glyn Davies | Conservative Party |
| Liberal Democrats | Evan Harris | Oxford West and Abingdon | Science Spokesman (2008-2010) | 1997 | Nicola Blackwood | Conservative Party |
| Liberal Democrats | Susan Kramer | Richmond Park | Transport Spokesman (2008-2010) | 2005 | Zac Goldsmith | Conservative Party |
| Liberal Democrats | Paul Rowen | Rochdale | Work and Pensions Spokesman (2008-2010) | 2005 | Simon Danczuk | Labour Party |
| Liberal Democrats | Sandra Gidley | Romsey, contesting Romsey and Southampton North | Health Spokesman (2006-2010) | 2000 | Caroline Nokes | Conservative Party |
| Liberal Democrats | Richard Younger-Ross | Teignbridge, contesting Newton Abbot | Heritage Spokesman (2008-2010) | 2001 | Anne-Marie Morris | Conservative Party |
| Conservative | Nigel Waterson | Eastbourne | | 1992 | Stephen Lloyd | Liberal Democrats |
| Conservative | David Heathcoat-Amory | Wells | | 1983 | Tessa Munt | Liberal Democrats |
| Democratic Unionist Party | Peter Robinson | Belfast East | Leader of the DUP and First Minister of Northern Ireland (2008-2016) | 1979 | Naomi Long | Alliance Party of Northern Ireland |
| Respect | George Galloway | Bethnal Green & Bow, contesting Poplar and Limehouse | | 2005 | Jim Fitzpatrick | Labour Party |
| Scottish National Party | John Mason | Glasgow East | | 2008 | Margaret Curran | Labour Party |
| Independent | Bob Spink | Castle Point | | 2001 | Rebecca Harris | Conservative Party |
| Independent | Andrew Pelling | Croydon Central | | 2005 | Gavin Barwell | Conservative Party |
| Independent | Frank Cook | Stockton North | | 1983 | Alex Cunningham | Labour Party |
| Independent | Richard Taylor | Wyre Forest | | 2001 | Mark Garnier | Conservative Party |
| Blaenau Gwent People's Voice Group | Dai Davies | Blaenau Gwent | | 2006 | Nick Smith | Labour Party |
