GPD1L
# GPD1L

GPD1L is a human gene. The protein encoded by this gene contains a glycerol-3-phosphate dehydrogenase (NAD+) motif and shares 72% sequence identity with GPD1.

## Structure

GPD1L contains the following domains:

* N-terminal – NAD+ consensus binding site
* a site homologous to the cardiac sodium channel SCN5A
* C-terminal lysine-206 residue

## Tissue distribution

Northern blot analysis detected a single GPD1L transcript in all tissues examined except liver. Highest expression was in heart and skeletal muscle.

## Disease linkage

Mutations in the GPD1L gene are associated with the Brugada syndrome and sudden infant death syndrome.

