List of highways numbered 281
# List of highways numbered 281

The following highways are numbered 281:

## Canada

* Quebec Route 281

## Japan

* Japan National Route 281

## United States

* U.S. Route 281
* Alabama State Route 281
* Arkansas Highway 281
* California State Route 281
* Florida State Road 281
* Georgia State Route 281
* Iowa Highway 281
* Kentucky Route 281
* Maryland Route 281
* Minnesota State Highway 281 (former)
* Montana Secondary Highway 281 (former)
* New Mexico State Route 281
* New York State Route 281
* North Carolina Highway 281
* North Dakota Highway 281
* Ohio State Route 281
* Oklahoma State Highway 281A
* Oregon Route 281
* Pennsylvania Route 281
* South Carolina Highway 281
* Tennessee State Route 281
* Texas State Highway 281 (former proposed)
   * Texas State Highway Loop 281
   * Farm to Market Road 281 (Texas)
* Utah State Route 281 (former)
* Washington State Route 281

| Preceded by 280 | Lists of highways 281 | Succeeded by 282 |
| - | - | - |
