DPYS
# DPYS

Dihydropyrimidinase is an enzyme that in humans is encoded by the DPYS gene.

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

## Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.

* ↑ The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601".
