List of defunct airlines of Uruguay
# List of defunct airlines of Uruguay

This is a list of defunct airlines from Uruguay.

| Airline | IATA | ICAO | Callsign | Commenced operations | Ceased operations | Notes |
| - | - | - | - | - | - | - |
| Aero Regionales | | | | 1994 | 1995 | |
| Aero Uruguay | UO | AUO | UNIFORM OSCAR | 1977 | 2005 | |
| Aerolineas Regionales Uruguayas | | RAU | ARUSA | 1993 | 1994 | Renamed to Aero Regionales |
| Aerolíneas Colonia | KO | AKO | ARCO | 1957 | 1987 | |
| Aerolineas Uruguayas | | | | 1968 | 1968 | |
| Aerosur Uruguay | QE | ASU | | 1990 | 1993 | |
| Atlantida Linea Aérea Sudamericana | HP | | | 1977 | 1979 | |
| Alas Uruguay | YZ | ALY | | 2013 | 2016 | |
| Amaszonas Uruguay | Z7 | AUZ | URUGUAYO | 2015 | 2021 | |
| Aviasur | | | AVIASUR | 1995 | 1996 | |
| Azul Uruguay | | | | 2017 | 2017 | Formed by Azul Brazilian Airlines. Never launched. |
| BQB Líneas Aéreas | 5Q | BQB | | 2010 | 2015 | Assets taken by Línea Aérea Amaszonas to create Amaszonas Uruguay. |
| Compañía Aeronáutica Uruguaya | | | | 1936 | 1967 | |
| COTASA Taxi Aereo | | | | 1961 | 2004 | |
| Lapsa | | | | 1962 | 1995 | |
| Linea Aerea Rio Platense | | | | 1961 | 1969 | |
| PLUNA | PU | PUA | PLUNA | 1936 | 2012 | |
| Transcontinental Sur | | TCT | | 1992 | 2007 | |
| Transporte Aéreo Militar Uruguayo | | | TAMU | 1959 | 2003 | |
| Uair | UE | | | 2002 | 2005 | |
