Sodium-dependent neutral amino acid transporter B(0)AT2
# Sodium-dependent neutral amino acid transporter B(0)AT2

Sodium-dependent neutral amino acid transporter B(0)AT2 is a protein that in humans is encoded by the SLC6A15 gene.

## Function

SLC6A15 shows structural characteristics of an $Na^+$ and $Cl^−-dependent$ neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.

## Clinical relevance

Variants of this gene linked with depression are associated with reduced SLC6A15 expression in the human hippocampus, as well as decreased volume of this brain region.

