Cis-acting replication element
# Cis-acting replication element

Cis-acting replication elements bring together the 5′ and 3′ ends during replication of positive-sense single-stranded RNA viruses (for example Picornavirus, Flavivirus, coronavirus, togaviruses, Hepatitis C virus) and double-stranded RNA viruses (for example rotavirus and reovirus).

