List of number-one hits of 1988 (Flanders)
# List of number-one hits of 1988 (Flanders)

These hits topped the Ultratop 50 in the Flanders region of Belgium in 1988.

| Date | Artist | Title |
| - | - | - |
| January 2 | George Michael | "Faith" |
| January 9 | Rick Astley | "When I Fall in Love" |
| January 16 | Rick Astley | "When I Fall in Love" |
| January 23 | T'Pau | "China in Your Hand" |
| January 30 | T'Pau | "China in Your Hand" |
| February 6 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| February 13 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| February 20 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| February 27 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| March 5 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| March 12 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| March 19 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| March 26 | Bill Medley & Jennifer Warnes | "(I've Had) The Time of My Life" |
| April 2 | Billy Ocean | "Get Outta My Dreams, Get into My Car" |
| April 9 | Billy Ocean | "Get Outta My Dreams, Get into My Car" |
| April 16 | Eddy Grant | "Gimme Hope Jo'anna" |
| April 23 | Eddy Grant | "Gimme Hope Jo'anna" |
| April 30 | Eddy Grant | "Gimme Hope Jo'anna" |
| May 7 | Eddy Grant | "Gimme Hope Jo'anna" |
| May 14 | Eddy Grant | "Gimme Hope Jo'anna" |
| May 21 | Eddy Grant | "Gimme Hope Jo'anna" |
| May 28 | Mory Kante | "Yé ké yé ké" |
| June 4 | Mory Kante | "Yé ké yé ké" |
| June 11 | Mory Kante | "Yé ké yé ké" |
| June 18 | Fleetwood Mac | "Everywhere" |
| June 25 | S'Express | "Theme From S'Express" |
| July 2 | S'Express | "Theme From S'Express" |
| July 9 | Michael Jackson | "Dirty Diana" |
| July 16 | Michael Jackson | "Dirty Diana" |
| July 23 | Tracy Chapman | "Fast Car" |
| July 30 | Tracy Chapman | "Fast Car" |
| August 6 | Tracy Chapman | "Fast Car" |
| August 13 | Salt-N-Pepa | "Push It" |
| August 20 | Salt-N-Pepa | "Push It" |
| August 27 | The Pasadenas | "Tribute (Right On)" |
| September 3 | The Pasadenas | "Tribute (Right On)" |
| September 10 | The Pasadenas | "Tribute (Right On)" |
| September 17 | Sam Brown | "Stop!" |
| September 24 | Sam Brown | "Stop!" |
| October 1 | Sam Brown | "Stop!" |
| October 8 | Sam Brown | "Stop!" |
| October 15 | Yazz | "The Only Way Is Up" |
| October 22 | Yazz | "The Only Way Is Up" |
| October 29 | Phil Collins | "A Groovy Kind of Love" |
| November 5 | Phil Collins | "A Groovy Kind of Love" |
| November 12 | Womack & Womack | "Teardrops" |
| November 19 | Womack & Womack | "Teardrops" |
| November 26 | Womack & Womack | "Teardrops" |
| December 3 | Wee Papa Girl Rappers | "Wee Rule" |
| December 10 | Wee Papa Girl Rappers | "Wee Rule" |
| December 17 | Enya | "Orinoco Flow" |
| December 24 | Enya | "Orinoco Flow" |
| December 31 | Enya | "Orinoco Flow" |
