Swimming at the 1991 Pan American Games – Women's 4 × 100 metre medley relay
# Swimming at the 1991 Pan American Games – Women's 4 × 100 metre medley relay

The women's 4 × 100 metre medley relay competition of the swimming events at the 1991 Pan American Games took place on 17 August. The last Pan American Games champion was the United States.

## Results

All times are in minutes and seconds.

| KEY: | q | Fastest non-qualifiers | Q | Qualified | GR | Games record | NR | National record | PB | Personal best | SB | Seasonal best |
| - | - | - | - | - | - | - | - | - | - | - | - | - |

### Final

The final was held on August 17.

| Rank | Name | Nationality | Time | Notes |
| - | - | - | - | - |
| | Jodi Wilson Dorsey Tierney Angie Wester-Krieg Ashley Tappin | United States | 4:12.51 | GR |
| | Ana Azevedo Glicia Lofego Paoletti Filippini Celina Endo | Brazil | 4:23.45 | |
| | - - - - | Mexico | 4:25.94 | |
| 4 | - - - - | Puerto Rico | 4:30.65 | |
| 5 | - - - - | Argentina | 4:38.94 | |
| 6 | - - - - | Canada | DQ | |
| 7 | - - - - | - | - | |
| 8 | - - - - | - | - | |
