1946 U.S. National Championships – Women's singles
# 1946 U.S. National Championships – Women's singles

First-seeded Pauline Betz defeated fifth-seeded Doris Hart 11–9, 6–3 in the final to win the women's singles tennis title at the 1946 U.S. National Championships.

## Seeds

The tournament used two lists of players for seeding the women's singles event; one for U.S. players and one for foreign players. Pauline Betz is the champion; others show in brackets the round in which they were eliminated.

* Pauline Betz (champion)
* Margaret Osborne (quarterfinals)
* Louise Brough (quarterfinals)
* Dorothy Bundy (first round)
* Doris Hart (finalist)
* Patricia Todd (semifinals)
* Shirley Fry (first round)
* Mary Arnold (semifinals)
* Jean Bostock (third round)
* Kay Stammers Menzies (third round)
* Raymonde Jones (first round)
* Mrs. Pat Adams (first round)
* Tara Deodhar (first round)

## Draw

### Final eight

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Finals | Finals | Finals | Finals |
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| 1 | Pauline Betz | 6 | 3 | 6 | | | | | | | | |
| | Gussie Moran | 1 | 6 | 2 | | | | | | | | |
| | Gussie Moran | 1 | 6 | 2 | 1 | Pauline Betz | 6 | 6 | | | | |
| | | | | | 6 | Patricia Todd | 2 | 3 | | | | |
| 6 | Patricia Todd | 6 | 6 | | 6 | Patricia Todd | 2 | 3 | | | | |
| 3 | Louise Brough | 2 | 2 | | | | | | | | | |
| 3 | Louise Brough | 2 | 2 | | | | | | 1 | Pauline Betz | 11 | 6 |
| | | | | | | | | | 5 | Doris Hart | 9 | 3 |
| 8 | Mary Arnold | 6 | 6 | | | | | | | | | | 5 | Doris Hart | 9 | 3 |
| | Dorothy Head | 2 | 1 | | | | | | | | | |
| | Dorothy Head | 2 | 1 | | 8 | Mary Arnold | 3 | 2 | | | | |
| | | | | | 5 | Doris Hart | 6 | 6 | | | | |
| 5 | Doris Hart | 6 | 5 | 7 | 5 | Doris Hart | 6 | 6 | | | | |
| 2 | Margaret Osborne | 4 | 7 | 5 | | | | | | | | |
