Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The non-protein molecules that bind to the protein part of the enzyme constitute the complete enzyme are called: 
 Options:  <1> Cofactors <2> Metallic ions <3> Coenzymes. <4> Vitamins <5> Prosthetic groups.
