Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The coupling of a terminal alkyne with vinyl halide by palladium catalysis is known as the reaction of: 
 Options:  <1> Heck <2> Suzuki <3> Sonogashira. <4> Stille <5> Nicolaou
