Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Pyruvate carboxylase is allosterically activated by one of the following compounds, what is it? 
 Options:  <1> Pyruvate. <2> Acetyl-CoA. <3> Malate. <4> Oxalacetate. <5> NAD +.
