Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Which of the following situations would noticeably decrease the transcription of a gene? 
 Options:  <1> The presence of a repressor and an inducing molecule. <2> The binding of RNA polymerase to DNA. <3> The presence of a repressor and a correpressor molecule. <4> The presence of an activator and its signal molecule. <5> The presence of a mutated repressor that could not bind to DNA.
