Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: According to the Arrhenius equation (k = A e-Ea / RT): 
 Options:  <1> The speed of a reaction is directly proportional to the temperature. <2> A high activation energy implies that the speed constant depends markedly on the temperature. <3> The pre-exponential factor or frequency factor (A) is dimensionless. <4> The activation energy depends on the temperature. <5> The activation energy is always negative.
