Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: According to the N-terminal end rule, the N-terminal residue of a protein determines: 
 Options:  <1> Its folding rate. <2> Its intracellular concentration. <3> Its intracellular location. <4> Your average life <5> Your translation rate
