Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The three human chromosomes estimated to contain fewer genes are: 
 Options:  <1> 21, 22 and Y. <2> 18, 22 and Y. <3> 18, 21 and Y. <4> 13, 21 and Y. <5> 13, 22 and Y.
