Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The exergonic reactions of metabolism: 
 Options:  <1> Consume free energy. <2> They are thermodynamically favorable. <3> They are always quick reactions. <4> They do not require the action of enzymes. <5> They have high values ​​of activation energy.
