Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: An essential characteristic of plasmids is: 
 Options:  <1> Be able to integrate into the genome of the host cell. <2> Direct the process of bacterial conjugation. <3> Carry genes for antibiotic resistance. <4> Replicate autonomously. <5> Being circular DNA molecules.
