Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The DiGeorge syndrome is linked to: 
 Options:  <1> A defective development of the thymus. <2> An alteration of the secondary lymphoid tissue. <3> An alteration of the M cells <4> A maturation defect of B lymphocytes <5> An alteration in the regulatory systems of the complement.
