Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: A plasmid contains necessarily: 
 Options:  <1> Genes of resistance to antibiotics. <2> Origin of replication. <3> Integrons <4> Genes of transfer by conjugation. <5> Transposons.
