Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: During a prolonged fast: 
 Options:  <1> The low level of blood sugar decreases the secretion of glucagon and increase the insulin. <2> Decreases the concentration of acetyl-CoA. <3> The main fuel of the organism happens to be the fatty acids and the ketone bodies. <4> The proteins are degraded and replenished immediately. <5> The brain and the heart use fatty acids as fuels.
