Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The cyclization of monosaccharides: 
 Options:  <1> It is an enzymatically catalyzed reaction. <2> It gives rise to enantiomers D and L. <3> It happens in the trios and tetrosas. <4> Generates a new asymmetric C, called anomeric C. <5> In ketoses it is produced by the formation of a hemiacetal bond.
