Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Question linked to the image nº16 Patient of 48 years smoker. Consultation due to symmetrical and bilateral reddening in both feet accompanied by burning pain (image). The general examination, the neurological examination and the peripheral pulses are normal. The analytical highlights: Hb 16.8 g / dl, leukocytes 12,400 / mm3, platelets 720,000 / mm3. Biochemistry: Glucose 87 mg / dl, Creatinine 0.7 mg / dl, Protein 7.5 g / dl, Calcium 9.4 mg / dl, GOT 40 U / L, GPT 35 U / L, GGT 64 U / L, FA 124 U / L, LDH 187 U / L, VSG 24 mm / h. Hemostasis and normal immunoglobulins. Serology against hepatitis B and C negative virus. What is the most likely diagnosis? 
 Options:  <1> Livedo reticularis. <2> Erythromelalgia. <3> Buerger's disease <4> Systemic mastocytosis. <5> Mixed cryoglobulinemia.
