Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Statins are used to reduce cholesterol levels and act as analogs of the transition state of an enzyme involved in its biosynthesis. What enzyme is it? 
 Options:  <1> 14-Alpha-demethylase. <2> Hydroxymethylglutaryl coenzyme A (HMGCoA) reductase. <3> Cyclooxygenase 2 (COX-2). <4> Squalene epoxidase. <5> Aromatase
