Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Stimulates the separation of DNA strands during replication: 
 Options:  <1> Primasa <2> DNA ligase. <3> The single chain DNA binding proteins. <4> Helicasa <5> DNA polymerase I.
