Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Which of the following statements about the steady-state infusion of a drug is true? 
 Options:  <1> The concentration reached in steady state of equilibrium depends exclusively on the clearance. <2> The time necessary to reach the steady state of equilibrium depends on the volume of distribution. <3> The concentration reached in a steady state depends exclusively on the elimination half-life. <4> The concentration achieved in the steady state equilibrium depends on the clearance and the infusion rate. <5> The time required to reach the steady state of equilibrium depends on the clearance.
