Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: In an animal species, the value of the elimination rate constant of a drug with linear pharmacokinetic behavior depends on: 
 Options:  <1> The route of administration. <2> The dose of drug administered. <3> The percentage of administered dose that arrives unaltered to the general circulation. <4> The speed at which the drug reaches systemic circulation. <5> The distribution and elimination of the drug.
