Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Glycolysis and hepatic gluconeogenesis are regulated reciprocally by facilitated hormonal mechanisms, in addition to an important metabolite that determines whether glucose should be synthesized or degraded. Which?: 
 Options:  <1> Fructose 6-phosphate. <2> Fructose 1,6-bisphosphate. <3> Fructose 2,6-bisphosphate. <4> Pyruvate. <5> Lactate
