Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: In the formation of the skin they intervene: 
 Options:  <1> Only the ectoderm. <2> The ectoderm, mesoderm and cells of the neural crest. <3> The ectoderm and mesoderm. <4> The ectoderm and cells of the neural crest. <5> Only the mesoderm.
