Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Which of the following is a poor prognostic factor in acute lymphoblastic leukemia ?: 
 Options:  <1> Age 1-9 years. <2> Phenotype B. <3> Karyotype with translocation 9; 22. <4> Leucocytosis of 25,000 / microL. <5> Hyperploid DNA index.
