Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: In the treatment of major depressive disorder, what are the advantages of selective serotonin reuptake inhibitors (SSRIs) compared to tricyclic antidepressants? 
 Options:  <1> They are more effective. <2> They have been used for a longer time, while tricyclic antidepressants are more modern and are not well known. <3> They have fewer side effects. <4> Its efficacy has been proven in controlled studies, while tricyclic antidepressants have not yet been evaluated in controlled studies. <5> They have no clear advantage.
