Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Somatomedin IGF-1 causes: 
 Options:  <1> Secretion of GHRH. <2> Protein catabolism. <3> Hyperglycemia <4> Activation of osteoblasts <5> GH secretion
