Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The reovirus .: 
 Options:  <1> They are released from the cell by budding. <2> They replicate their genetic material in the cell nucleus. <3> They have a lipid envelope. <4> They form virions resistant to acid pH. <5> They are transmitted by blood.
