Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: For a drug to permeate through the cornea, you must: 
 Options:  <1> Be totally ionized. <2> Present a very high polarity. <3> Join the lysozyme that is present in the tear fluid. <4> Present a certain lipophilicity and a minimum degree of water solubility. <5> Have weak acid character.
