Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Which of the following drugs obtained by means of molecular engineering techniques is not applicable in the treatment of rheumatoid arthritis ?: 
 Options:  <1> Infliximab. <2> Denosumab. <3> Adalimumab. <4> Anakinra <5> Etanercept.
