Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The hormonal stimulation of the formation of the second messenger inositol 1,4,5-trisfosfato (IP3) quickly leads to the release of what other intracellular messenger: 
 Options:  <1> Cyclic AMP. <2> Prostaglandin <3> Calcium. <4> Leukotriene <5> Thromboxane
