Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: If after establishing the confidence interval with respect to a difference between two independent means, we find that the zero value is not in the interval: 
 Options:  <1> We can not make any decision regarding the null hypothesis of equality of means. <2> We can not reject the null hypothesis of equality between population means. <3> We must reject the null hypothesis of equality between population means. <4> We accept the null hypothesis of equality between the population means. <5> We reject the alternative hypothesis of equality between population means.
