Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: The number of pairs of metacentric chromosomes of the human karyotype is: 
 Options:  <1> 8 <2> 6 <3> Four. <4> 12 <5> two.
