Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: In the analysis of a pedigree of an autosomal dominant trait it is observed that: 
 Options:  <1> The trait appears more frequently in males. <2> The unaffected people do not transmit the trait. <3> The trait tends to skip generations. <4> The affected people have both affected parents. <5> The trait tends to appear in the progeny of related parents.
