Arizona is in North America.
Arizona ( [ ɛərᵻˈzoʊnə , _ ærᵻ - ] ) ( Hoozdo Hahoodzo [ xòːztò xɑ̀xòːtsò ] O'odham : Alĭ ṣonak [ ˡaɺi ˡʃonak ] ) is a state in the southwestern region of the United States . It is also part of the Western and the Mountain states . It is the sixth largest and the 14th most populous of the 50 states . Arizona 's border with Mexico is 389 miles ( 626 km ) long , on the northern border of the Mexican states of Sonora and Baja California . About one-quarter of the state is made up of Indian reservations that serve as the home of 27 federally recognized Native American tribes , including the Navajo Nation , the largest in the state and the United States , with more than 300,000 citizens .