Sennacherib's youngest son was born blind.
Esarhaddon ( Akkadian : Aššur-aḥa-iddina `` Ashur has given a brother '' ; אֵסַר חַדֹּן Ασαραδδων Asor Haddan ) was a king of the Neo-Assyrian Empire who reigned 681 -- 669 BC . He was the youngest son of Sennacherib and the West Semitic queen Naqi'a ( Zakitu ) , Sennacherib 's second wife . Sennacherib . He was assassinated in obscure circumstances in 681 BCE , apparently by his eldest son ( his designated successor , Esarhaddon , was the youngest ) .