[Effects] In the past, before direct-acting antivirals (DAAs), studies of patients with HIV-HCV coinfection showed that treatments have a much lower success rate in coinfected patients compared to HCV patients without HIV. With studies of sofosbuvir in HIV-HCV infected patients, success rates were much higher and comparable to the success rates for patients without HIV infection. [Factor] 
HIV coinfection
V i r a l l o a d
O n g o i n g u s e o f a l c o h o l
E t h n i c i t y
L e n g t h o f i n f e c t i o n
A d h e r e n c e ( t a k i n g m e d i c a t i o n s a s p r e s c r i b e d )
O b e s i t y
H I V c o i n f e c t i o n