[Reaction] Transfusion-associated acute lung injury (TRALI) [Symptom Description] TRALI is a syndrome of acute respiratory distress, often associated with fever, non-cardiogenic pulmonary oedema, and hypotension. Symptoms can develop within 2 to 8 hours after a transfusion ranging from mild to life-threatening. Most patients recover fully within 96 hours, and the mortality rate from this condition is less than 10%. [Pathophysiology] 
Pulmonary vascular effects are thought to occur secondary to cytokines in the transfused product or from interaction between patient white cell antigens and donor antibodies (or vice versa).