[Fucoxanthin] Thermodiamine
Thermodiamine, otherwise known as Evodiamine, is isolated from the unripe fruit of Evodia Rutaecarpa. In a recent study, (Kobayashi Y et al, 2001) when evodiamine was supplemented at 0.02% in the form of ethanol extract of Evodia fruits in a high-fat diet for 21 days, the body weight, perirenal fat weight and epididymal fat weight were found to be significantly reduced compared to the control group. The treated groups on a high fat diet gained significantly less body fat than the control groups. Thermodiamine appears to support an increase in lipolytic (fat burning) activity through several mechanisms. Similar to the action of cayenne pepper, evodiamine appears to effect receptors known as vanilloids. These receptors are involved in the regulation of body temperature. However, it does so without the common side effects of burning and indigestion. Secondly, evodiamine may support an increased output of catecholamines. Since catecholamines are intimately involved in fat loss, evodiamine assists in supporting healthy fat oxidizing pathways. Studies suggest evodiamine may support an increase in peripheral heat loss. This result indicates an increase in energy expenditure.