### Instruction:

Extract the cause and effect entities from the following sentence:
However, in case of a hot spot the prime science comes from the variability of the spectra

### Assistant:

NOT_RELEVANT: However
KEYWORD: in case of
VARIABLE: the prime science
CONDITION: comes from the variability of the spectra
CAUSE_1: a hot spot
EFFECT_1: the prime science comes from the variability of the spectra

