 expert question: I took Moclobemide for the first time and I had excellent effects, high mood, mental clarity, confidence, I was really well unfortunately the effect only lasted 2 months, then overnight it stopped working like this 'I'm done taking the drug. After 8 months I tried to take it again, thinking that the 8-month break from the last intake was enough to get back the beneficial effects I had had, unfortunately this time I did not feel any effect. The same thing to a lesser extent has happened to me with other antidepressants. Is there any expert who can tell me why this happens? Do you have any hypotheses why this happens? Has it happened to others? Thanks