I was doing well with Latuda + Lithium but had a devastating depression + anger.
So Latuda was replaced by Seroquel but I fainted and stopped it.
I was only on Lithium but my doctor insisted that my depression is huge and that Lithium wouldn't let me go to maniac phase and that I can take Zoloft as previously (I used to took Zoloft for depression until I became maniac and was diagnosed bipolar).