Hi all,

I have had some success with cocktailing medicines. The most useful medicines for me are quetiapine (Seroquel®), 150 mg and lamotrigine (Lamictal®), 200 mg. I have in the past also used diazepam (Valium®), 5 mg as a rescue therapy for debilitating anxiety.

While I had success with sertraline (Zoloft®), 200 mg for the relief of depression and anxiety, I have been asked to switch to vortioxetine (Trintellix®/Brintellix®), 10 mg for the same symptoms. From what I read online, it has a similar review profile as quetiapine: if it works it’s great, but it doesn’t always work, and when it doesn’t, it’s awful.

What are your experiences?