So I started taking high dose niacin (yes with that beautifully awful flush), at about 3000mg daily split into 3 doses as Dr Abram Hoffer suggested. And that same day I felt so much more connected to life and genuinely felt happiness, like I could register smiles and when music made me feel good. So I started increasing the dose, and each increase I felt better. So then I thought bout it and realized the past few years the symptoms I noticed I was having were weird skin lesions and other skin issues, intense diarrhea (ik gross but it's true) as well as anxiety, depression, and even some brain fog. Now I'm realizing that I was probably dealing with a low grade version of pallegra