I take quite the cocktail including both Modafanil and Wellbutrin XL (neither of which have caused weight loss for me). 

First off, I had my doctor prescribe naltrexone. Just the regular 50 mg tablets. It’s a wild ride at first (you feel silly the first few days and sleep like crap for a few weeks) but it kills my food cravings. Every now and then I’ll see something that looks appealing or I’ll have a snack, but gone are the days of feeling like a human termite.

Second, I went through Alpha Medical’s weight loss program. It sucks at first because I had to start on metformin which gave me the worst gastric side effects ever (diarrhea if you must know) but once I told them I couldn’t take it, they opened up a plethora of other options, one of which is Mounjaro. It’s a once a week shot in the stomach (one of those tiny nano pen needles). My insurance wanted a PA but! Thanks to one of the wonderful pharmacists at CVS, I found out that with the coupon from the manufacturer, you can get it for $25. Regardless of what your insurance says.

I’ve gone from 206 to 193 in about three weeks with zero exercise. I have a desk job where I work from home. I have very little appetite and eat a fraction of what I ate before at meals. The stuff is amazing. 

So in short - Mounjaro and naltrexone have caused weight loss for me while taking 3 mgs of Rexulti.