First time posting. Struggling with depression and anxiety. My doctor prescribed Fetzima. Started off at 20 mg for 2 weeks; I felt an improvement in mood , sleeping, eating etc..don’t know if it was placebo effect…I was actually functioning and wanting to do things….yeah it has been pretty bad. After 2 weeks at 20 mg ….my doctor increased me to 40mg. I have been on 40mg for 10 days and my anxiety is through the roof. I am irritable and just crusted with anger. I just don’t want to deal with things…even normal things that wouldn’t normally cause anxiety. I am thinking to talk to my doctor to go back down to 20mg….or get off this. I am not sure. If anyone has any experience, please share. Thank you so much! BTW I weened off Effexor 4 days before starting Fetzima. Only on Effexor for a month and a half. Wasn’t a good fit.