Hey guys. I'm looking for advice. I'm 25 year old guy, and have been dealing with severe anxiety/depression since before I can remember. I also just got a diagnosis of autism a little while ago. I've worked really hard to develop strategies to deal with day to day panic and anxiety, but I need advice on larger scale life stuff. 

I have this problem where I'll move into a new life situation and do fairly well coping with shit on the daily. But after the 6 month to 1 year mark of any project/job/school experience, I start to experience dread about some aspect about my life. At first it's easy to deal with, I just push through and ignore the little whispers. Then it gets harder. People say that the key to dealing with anxiety like this is to face the problem head on, to force yourself to recognize that you're being irrational. It doesn't work. Each time I bulldoze through the dread, the next time I have to face it is 10x worse. Eventually, I'm just a pitiful shell of obsessive fear and avoidant thought patterns. Then I give up. I move back to my hometown and deal with the fallout like a child. 

This has happened five times. Each time I feel like I have a better grasp on the situation, I surprise myself with the new and creative ways my anxiety circumnavigates my defenses. 

I'm so tired. I feel so done. I just want to do one thing that I don't ruin with this pattern. I've tried pretty much everything the therapists and psychiatrists have said, from meds to meditation, and they do wonders for the small stuff like social anxiety, but nothing for these situational, long-term thought monsters. I feel like I'm just hardwired for failure, like no matter how hard I try I'm destined to live off of the charity of others while I perpetually try and get my shit together. 

Am I alone in this? How have you dealt with this stuff?

Do I just give up? My family loves me but I know they're sick of this shit too. 
Thanks.