I have treatment-resistant depression which is devestating when im off medication and just as bad if not worse when off it. When people fail to respond to several anti-depressants it is often recommended to switch class or to switch the type of medication. The problem is.. I have now tried it all. Literally. 

SSRI, SNRI, TCA, MAOI, NDRI (wellbutrin), anti psychotics, mood stabilizers, dopamine agonists like pramiprexole, you fucking name it and ive tried it. I have an ADHD diagnosis which likely is contributing or causing the depression and every single medication has been ineffective there is well; vyvanse, dexidrene, strattera, ritalin IR/XR and guanfacine. Nothing else is available in my country. 

I've tried therapy, plenty of exercise and sunlight and all that stuff concurrently with treatment.

Guys what the fuck is supposed to be done in this situation. I gotta say im getting closer and closer to pulling the plug. Any advice? maybe someone has experienced the same?