Hi everyone,

I am having a lot of trouble with supplements like NAC, Alpha Lipoic Acid and Theanine making a glutamate / excitotoxic / kindling withdrawal feelings in the morning. This is especially problematic if I drink alcohol and take the NAC before. Has anyone else experienced this? My theory is that NAC or ALA are effectively modulating the glutamate system, either suppressing or using up glutamate so that when the glutamate rebound happens in the middle of the night it is making an already supressed glutamate situation from alcohol even worse. It is very frustrating because I definitely see good benefits from NAC evening me out at times and making me less compulsive. I also notice that NAC taken before makes me get more intoxicated quicker, all things based on others experiences on here should not be happening. Would greatly appreciate if anyone has had similar reactions but the kindling feeling is heightened anxiety, difficulty sleeping and feeling like I need to reach of an Ativan / Lorazepam (which I do not want to take). There have been times where I have taken NAC well into the next day, say middle of a Sunday and I get extreme anxiety / panic / sweating, feeling very glutamate storm or serotonin syndrome feeling.

Thanks :(