 Hi all,  


I've tried various medications over the years with very little success to help treat my severe anxiety/depression/agoraphobia. I was recently diagnosed with Borderline Personality Disorder. I have had limited success using Fluoxetine and Vortioxetine, but I discontinued because they either seemed to lose efficiency, or they seriously interacted with my other medications (I suffer with Cluster Headaches) - ie Sumatriptan injections, Zolmitriptan, Rizatriptan, causing me to suffer mild-moderate Serotonin Syndrome 📷  


The medications I can remember being prescribed over the years for anxiety/depression include the following -  
Citalopram  
Sertraline  
Venlafaxine  
Amitriptyline  
Mirtazapine  
Duloxetine  
Quetiapine  
Olanzapine  
Risperidone  
Aripiprazole  
Fluoxetine  
Vortioxetine  
Hydroxyzine  
Promethazine  


As a last throw of the dice I was considering using low dose Buprenorphine (Subutex here in the UK, which contains no Naloxone/Naltrexone)  


What are your thoughts/general consensus on me trying this route? I need some non-Serotonergic medication due to the Triptans I use to abort my Cluster Headaches.  


Any imput most welcome... Thanks in advance. 📷  


EDIT: I should add that I have had significant experience with Opiates (Oxy, Dihydrocodeine, Codeine, Morphine etc over the past 11 years)