Just over two years ago I had a nervous breakdown due to my autism and ended up in the hospital for 3 days. They put me on a low dose of Zyprexa to calm me down. It has worked but I have put on 75 pounds since starting it. I also have no energy and my legs ache severely when I try to walk more than an 8th of a mile around my neighborhood, so I can't get any exercise and therefore live a very sedentary lifestyle. What I'm wondering is, do people tend to lose the weight they've gained once they stop the medication? All my doctors and therapists agree that they think it's safe for me to come off it now and I have their support, but it's proving to be hard. I've gone from 165 to 240 pounds and I just feel gross and slobby.