It doesn't matter how hard you try, your parents will still age and die, your pets will die before you, you'll always encounter hardships, you always will lose your health eventually.  It's all inevitable.  

What's the point of trying?  There's no scenario where you put forth so much effort, that you succeed in avoiding all the bad that's in the future. 

I'm going to post my motorcycle up for sale and as I'm writing the ad, I'm thinking wtf is the point of it all.  I'll put this money into my savings account but what's the point?  What's the point if a number goes up a little bit in my bank account?  It's not enough to change my life or anything.  What's the point of doing the "responsible thing" when my life doesn't change for the better in the slightest?