Been on it for about a week, i got diagnosed a while back with a Mixed Anxiety-Depression disorder, i'm currently on 10Mg Escitalopram and 10Mg Mirtazapine at bedtime, i've only been on Mirtazapine for a week but i would say it is working for me, it also knocks me out at bedtime and i sleep well, although i am a bit groggy in the morning.