I am wondering if combining Topamax with Wellbutrin would help with some of the common Wellbutrin side effects like increased anxiety and irritability. I struggle with mood lability in addition to the others and am worried that the Wellbutrin will make me unbearable to be around during the adjustment period.

I've taken Topamax in the past for migraines and realized it helped a lot with mood lability and irritability. I'm not sure I noticed much about anxiety, but I'm just a high-anxiety individual in general.

Has anyone tried this combination with good results? I don't know what dosage my psych is wanting to put me on for Wellbutrin (I'm assuming 150mg), but I do know I've taken 100mg of Topamax in the past with good results.