I‘ve tried 13 meds now, all with very little (placebo like) to mostly no effects at all, mostly really zero, nada, except for side effects.

Gabapentin &amp; Mirtazapine were the ones that had a subtle positive effect on depression and social anxiety.
Escitalopram had a huge effect but lasted only one week (why? Idk as all other SSRI/SNRIs had no effect at all)

Im trying to increasy my mood to more positive, be less anxious about the future, decrease my social anxiety (very important! As its the biggest source of my depression) and with this get more social, talkative and outgoing. I socially isolate myself very much and I think every human needs socializing to be happy (friends as well as romance).

I‘d be very happy if you could abswer me following questions:

What have been your experiences with Wellbutrin (Bupropion) for depression and especially interesting Social Anxiety?

What would you describe the effects like regarding mood/depression, future anxiety, social anxiety/sociability/talkativeness, energy/lethargy, cognition (memory, focus) &amp; anhedonia?

How long does it take until it starts showing significant effects?

What dose are you on?