I have a few questions for people (mostly women, but also cannabis users) who are taking Lamotrigine. 

I have been taking it for a few months. I was sitting at 150mg for about two weeks, and I honestly felt like it was helping a lot and I was a bit more stable and in control. And then I got to my final dose of 200mg a few weeks ago and I feel everything went to shit ! 

The episodes are so aggravated now. I feel extremely sensitive and scared all of the time. I upped my dose and started PMSing the next week, and it got so bad that I have been lashing out every day since then. I thought maybe it’s just because I’m so hormonal and the increase collided with the PMS. My period was so late and I read that Lamotrigine can do that, so my PMS symptoms were extended a week and a half past what they should’ve been, and they were a lot more intense. 

Has this happened to any of you before? Will the intensity of my feelings, and the extreme sensitivity go away when I get “settled” into the 200mg? Or is this not normal and I should get back to 150mg when I can tell my psychiatrist? It didn’t happen with any of the previous increases. 

Now about the weed: I was a daily smoker for about two years, it helped immensely in stopping an episode and it also just relaxed me with the right Indica strain, or it makes me happy and euphoric when it’s more a sativa/hybrid. Up until 150mg, using it was still fine and it did what it usually does. Once I made the switch to 200, it stopped being fine. 

Now, both strains I’ve tried, even ones low in THC count, are giving me panic attacks. I was using a strain while on the 150 that I really liked, it was working great for me, but once I did the increase that very same strain made me freak out and panic so hard that I threw up. Thought it was a one time thing so I went and got a nice indica, and it happened again. So I thought maybe I was using too much, so I tried a really tiny hit the next day and it still gave me the bad anxiety, but I didn’t throw up that time. So I have stopped smoking. 

Has this happened to anyone else??? Note that I haven’t tried smoking actual flower since I upped the dose, all three times were using my dab pen. Is this normal? Do lamotrigine and marijuana just collide in a bad way? Because for the first few months trying to get to my final dose, they didnt collide at all. Pleaaase tell me if this is normal. Also, if this HAS happened to you, would smoking flower maybe be better than concentrates? Or did it happen whilst using flower? Does this even have anything to do with lamotrigine at all?? 