I’m really curious because I know from ADHD medication, methylphenidate, is a dopamine and norepinephrine reuptake inhibitor and that works immediately. While obviously they’re completely different in action, both methylphenidate and sertraline are neurotransmitter reuptake inhibitors, and dopamine, norepinephrine and serotonin are the most major chemicals that influence mood, and each other as well.

I’ve been really depressed lately to a very troubling point, and I’m not diagnosed any depressive disorder so I have no antidepressants, but my mother does. She let me try one 50mg sertraline capsule and it seemed to actually work? Ever since I took it almost 24 hours ago my thoughts have been clear, not negative or depressive at all. I’m prescribed Vyvanse for my ADD which was in effect while I took the sertraline.

I was able to put myself in bed to sleep without procrastination or anything sort of distraction, which isn’t the work of my ADD medication as it’s a stimulant, keeping me awake.  I did have trouble falling asleep, though, but that may have been a mix of sedative effects from the antidepressant and stimulant keeping me awake.

Anyways, it seemed to work, and since I took it I’ve been feeling normal. Could this be possible or am I just having an incredible placebo that fixed my low mood and other symptoms?