When I see that I have a reply to a comment it often makes me anxious. One of the dumbest parts of my particular flavor of anxiety. Anyway, I got into the habit of always disabling reply notifications. Now if I want to see how a comment was received when I'm feeling good I can just go to my comment history in my Profile. It's been very nice, especially in political subreddits.   


After you comment click the three dots next to Edit and then uncheck the "Send Me Reply Notifications" box. You have to do it for every post but it doesn't take but a sec.