I have been on Depakote for 2 years for anxiety and depression, but I had to get off of them because it was causing me to have extremely high liver enzymes. Ever since then, I have been completely off of meds. It has been 1.5+ years since I have been off of meds. However, I deal with debilitating anxiety and depression on a daily basis now. I’ve tried everything to get better, but I’ve only seen minimal improvements. I’m thinking about going back on meds as a last resort. The psychiatric nurse I spoke with recommend that I start abilify. I know that researches shows no or rare permanent health complications arising from psychiatric meds (unless it’s meds that are known to commonly cause health issues such as lithium and depakote), but I keep thinking at the back of my head that these meds can’t be good for you long term. Abilify is an antipsychotic and seems like a more harmful psychiatric med compared to other ones. It seems like Zoloft is the least harmful med if it’s one of the safest med that can be taken during pregnancy (if a med doesn’t have a great risk of harming  a fetus, then I believe that it also wouldn’t be that harmful for adults). I just feel so conflicted because I feel reluctant to get back on psychiatric meds, but I’m exhausted from living everyday with anxiety and depression. If anything, I’d like to give Zoloft a try, but I’ve read so many negative things about it, so I’m thinking maybe abilify is the best choice. Have you guys had experience with these two drugs? Has it helped? Have you felt any long term effects from them?