Has anyone here had any success at all on medication, or has most of your success been based on DBT or other kinds of therapy?

I'm about ready to give up on meds altogether, I've been playing the "let's try this, no, let's try this" game for years upon years with no avail, at this point I'm so frustrated I just want to throw my pills at the wall. 

Edit: Specifically, right now I'm trying topamax due to the fact that it doesn't cause weight gain (I'm at a risk for self image problems and eating disorders, so I pretty much will no longer take anything that will cause me to gain weight after seroquel caused me to gain 60 pounds :( ) also on xanax for "emergencies", I'm thinking about just keeping that and dropping the "daily" stuff because I never really feel like it does anything for me, not looking for a magic pill to fix all my problems, but its as if it doesn't even relieve any symptoms. 
