I'm the bipolar part of the relationship, and I'm also on the autistic spectrum.
We've been in a relationship for 3 years, which for the most part is perfect. We get along well, we spend a lot of time together, and we're even thinking about moving in together.
But sometimes, we have some situations that make me question whether we will be able to deal with coexistence in the long term.
For example, due to my sensory sensitivity and social phobia (caused by both bipolar and autism) leaving the house can be quite challenging, but with lots of therapy and the right medication, I do it with some effort. It always involves an anxiety crisis, crying, self-esteem problems, which sometimes make me leave the house in a bad mood, but with time stabilizes, as I get used to the environment in which I will be. 
So, yesterday was one of those situations, my SO and I met at a restaurant, and I explained to him that it had been a hard time leaving home, but that everything was getting better. 
We ordered our drinks and our conidas, and I was having fun, until I realized that he was looking at me very cynically and making fun of everything I said, which made me very uncomfortable and insecure, and I ended up going into "defense mode", feeling the need to justify everything I was saying, and repeating myself several times, which only made him more annoyed with me.
I asked what was wrong, and the only thing he could tell me was that he couldn't do anything if I left the house in a bad mood, which is why he was being cynical and sarcastic all the time.
 I just got really annoyed with all that, I asked for the bill and we left.
I was taken by a feeling of helplessness for not having been able to de-escalate the situation, but at the same time I felt like an idiot for not having been able to realize that he was bothered before, and I also felt an absurd anger at his lack of acceptance and understanding ofmy difficulties. 
At the same time, I understand that it's not always easy to deal with the humor of a bipolar. I just wish we could talk about it without always having to be me to start the conversation.
If he had told me he was having a problem with my mood, instead of letting me believe we were fine (since I have a hard time "reading the room"), I could have changed my behavior, or maybe rescheduled the date to a more favorable day for both of us.
I feel that much of the wear is due to the lack of dialogue.
When i got home I têxteis him about everything i felt, he admitted he was annoyed, but he thought he didn't need to say anything because it would pass with time, and said that later we would talk about the general problem.
The conversation never came.
I wonder if these events, even if they are punctual, will not destroy everything when we are living together.
I wonder how to de-escalate the situation, but at the same time I wonder if I can even be in that place of rationalizing for both of us always, when sometimes I can't rationalize even for myself.
I love him, but maybe my condicionado is just too much for him to take.