During the 1970s, the museum held collections obtained from the Instituto de Cultura Puertorriqueña, pieces from the Mr. Herman Ferre's private collection, Santos from Dr. Luis F. Sala, archaeological discoveries donated by the Sociedad Guaynia de Arqueología e Historia, and miscellaneous donations from students and friends of the University, and for several years ran under the supervision of university professor Juan Manuel Ledesma Criado.