Firms that currently use Portland House for office space include American Express, Crossrail, Caxton FX, HomeAway UK, Owners Direct, Direct Ferries Ltd Orbus Software, Increase the Wedge, NetBooster, Somo Global, TradeDoubler, Wunder2, uSwitch, Upmystreet.com, Reef Television, Rentokil Initial, AkzoNobel, Monica Vinader Ltd and Regus.