Season 6 will explore ancestry stories of Jon Batiste, Sterling K. Brown, RuPaul, Jeff Goldblum, Terry Gross, Anjelica Huston, Gayle King, Justina Machado, Marc Maron, Melissa McCarthy, Queen Latifah, Jordan Peele, Nancy Pelosi, Zac Posen, Issa Rae, Isabella Rossellini, Amy Ryan, Eric Stonestreet, Diane von Furstenberg, Sigourney Weaver, Jeffrey Wright and Sasheer Zamata.