Located in Beyoğlu district of Istanbul in Turkey, Surp Yerrortutyun Church borders to Sahne sokak (formerly: Tiyatro sokak) in the west, to NNevizade​ sokak (formerly: Ermeni kilisesi sokak) in the north, to Solakzade sokak (formerly: Sol sokak) in the east and to buildings and Tokatlıyan Han on İstiklal Avenue in the south.