Eastern Connecticut, originally inhabited by the Quinnipiac Nation's sub-sachemships of the Eastern Nehantic, Podunk, and Wangunk, as well as the Narragansett, suffered more losses than western Connecticut, and so in 1506, after 80% population losses due to epidemics, the Pequotoog moved into the area from the upper Hudson region and pushed the survivors of the Narragansett into what is now Rhode Island, and the Nehantic wedged in close to the Connecticut River (Old Lyme).