text: Antipsychotics best for acute treatment of manic episodes | APhA DrugInfoLine
  Antipsychotics best for acute treatment of manic episodes
  Antipsychotic drugs were more effective than mood stabilizers for treating acute manic episodes in adults with bipolar disorder, according to a large meta-analysis. Risperidone (Risperdal—Janssen), olanzapine (Zyprexa—Lilly), and haloperidol outperformed other agents in terms of efficacy and tolerability.
  Berk M, Malhi GS. Should antipsychotics take pole position in mania treatment [editorial]? Lancet. 2011;378:1279–81.
  Cipriani A et al. Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis. Lancet. 2011;378:1306–15.