text: Plant responses to abiotic stress: the chromatin context of transcriptional regulation - Enlighten: Publications
  Plant responses to abiotic stress: the chromatin context of transcriptional regulation
  Asensi-Fabado, M. A., Amtmann, A. and Perrella, G. (2017) Plant responses to abiotic stress: the chromatin context of transcriptional regulation. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1860(1), pp. 106-122. (doi: 10.1016/j.bbagrm.2016.07.015) (PMID:27487458)
  122333.pdf - Published Version
  The ability of plants to cope with abiotic environmental stresses such as drought, salinity, heat, cold or flooding relies on flexible mechanisms for re-programming gene expression. Over recent years it has become apparent that transcriptional regulation needs to be understood within its structural context. Chromatin, the assembly of DNA with histone proteins, generates a local higher-order structure that impacts on the accessibility and effectiveness of the transcriptional machinery, as well as providing a hub for multiple protein interactions. Several studies have shown that chromatin features such as histone variants and post-translational histone modifications are altered by environmental stress, and they could therefore be primary stress targets that initiate transcriptional stress responses. Alternatively, they could act downstream of stress-induced transcription factors as an integral part of transcriptional activity. A few experimental studies have addressed this 'chicken-and-egg' problem in plants and other systems, but to date the causal relationship between dynamic chromatin changes and transcriptional responses under stress is still unclear. In this review we have collated the existing information on concurrent epigenetic and transcriptional responses of plants to abiotic stress, and we have assessed the evidence using a simple theoretical framework of causality scenarios.
  Amtmann, Professor Anna and Perrella, Dr Giorgio and Asensi-Fabado, Ms Maria Amparo
  Asensi-Fabado, M. A., Amtmann, A., and Perrella, G.
  First published in Biochimica et Biophysica Acta: Gene Regulatory Mechanisms 1860(1): 106-122
  60753 1 Molecular function and crop improvement potential of Histone Deacteylation Complex 1 Anna Amtmann Biotechnology and Biological Sciences Research Council (BBSRC) BB/K008218/1 RI MOLECULAR CELL & SYSTEMS BIOLOGY
  64815 1 EPIPRIMING: Keeping ready for battle: understanding fundamental mechanisms of establishment and maintenance of epigenetic marks underlying abiotic stress memory in plants. Anna Amtmann European Commission (EC) 627658 RI MOLECULAR CELL & SYSTEMS BIOLOGY