text: Keith R. Stayrook - Semantic Scholar
  Thomas P. Burris44
  John P. Bilezikian15
  54Thomas P. Burris
  19Douglas J. Kojetin
  19Laura A. Solt
  18Christine Crumbley
  18Patrick R. Griffin
  The nuclear receptors REV-ERBalpha (encoded by NR1D1) and REV-ERBbeta (NR1D2) have remained orphans owing to the lack of identified physiological ligands. Here we show that heme is a physiological… (More)
  The vitamin D receptor (VDR) functions as an obligate heterodimer in complex with the retinoid X receptor (RXR). These nuclear receptors are multidomain proteins, and it is unclear how various… (More)
  Thomas P Burris, Chahrzad R. Montrose, +13 authors Keith R. Stayrook
  Guggulsterone (GS) is the active substance in guggulipid, an extract of the guggul tree, Commiphora mukul, used to treat a variety of disorders in humans, including dyslipidemia, obesity, and… (More)
  Keith R. Stayrook, Kelli S. Bramlett, +5 authors Thomas P Burris
  The farnesoid X receptor (FXR; NR1H4) is a nuclear hormone receptor that functions as the bile acid receptor. In addition to the critical role FXR plays in bile acid metabolism and transport, it… (More)
  The nuclear receptors REV-ERBα (encoded by NR1D1) and REV-ERBβ (NR1D2) have remained orphans owing to the lack of identified physiological ligands. Here we show that heme is a physiological ligand of… (More)