text: Senior Medical Director-Clinical Development - Philadelphia - Adaptimmune Therapeutics plc | Ladders
  Senior Medical Director-Clinical Development at Adaptimmune Therapeutics plc in Philadelphia, PA
  The Senior Medical Director will work closely with other members of Adaptimmune's global Clinical, Research and CMC organizations to provide strategic direction into, as well as design, conduct and monitor the clinical development plans for specific clinical programs.
  The jobholder will have a strong clinical and specialty background in Oncology and/or Immuno-Oncology and will be a peer among the industry, medicine and/or academic community within the field of pharmaceutical medicine and/or area of Immuno-Oncology specialty.
  This Medical Director will provide expert scientific and clinical input to teams and business functions across Adaptimmune. You will be responsible for the impactful and inspiring leadership from the clinical, scientific and operational perspective towards accomplishing corporate goals. This responsibility will include mentorship and education of other physicians and scientists.
  Serve as a thought leader for cell therapy development within Adaptimmune, with participation in problem solving and decision-making activities with other research and development leaders to address challenging issues such as optimal lymphodepleting regimen, mechanism of toxicities, and product improvement; provide expert scientific and clinical input to teams under the direction of the Vice President of Clinical Development.
  Serve as a program level physician and medical monitor for clinical studies, with responsibility for protecting the integrity and conduct of clinical studies. Provide consultation to clinical operation colleagues on protocol design questions and answering protocol related questions from site investigators. Ensure that all clinical programs operate to the highest ethical and safety standards and in compliance with Good Clinical Practice ("GCP") and regulatory requirements.
  Provide strategic/tactical input into clinical development programs and data interpretation.
  Contribute to and author documents, including protocols, final study reports, and regulatory documents.
  Coordinate and develop information for reports submitted to Regulatory Agencies.
  Develop, maintain, and establish standards for strategic relationships with investigators, key opinion leaders and other stakeholders to enable and influence opportunities for our clinical trials and to advance presentations at congresses and other venues.
  Maintain up to date awareness of important advances within Immunotherapy Oncology through scientific literature, attendance at critical meetings and relationships with Key Opinion Leaders ("KOLs"). Liaise with internal and external medical community to follow developments within area of expertise.
  Represent Adaptimmune at high level external meetings, to share physician insights and perspectives in medical oncology in the treatment of solid tumor malignancies with our products. This may also include business development activities with current and prospective partners.
  Representing medical development and providing strategic input into decision making in collaboration with Senior Leaders across business functions, specifically contributing medical development expertise.
  M.D. with clinical development experience in pharma or academia preferred; with Research/translational/biomarker, immunology or oncology experience also preferred. Graduate of a recognized school of medicine with an M.D. degree or equivalent.
  Board Certification or Eligibility in Oncology/ Haematology or related field is preferred; specialty training and/or clinical experience and strong academic track record in Immuno-Oncology, Tumour Immunology, or Immunotherapy is preferred. Other specialties in medicine will also be considered.
  Drug development experience within pharmaceutical/biotech or academia required
  Ability to participate in the conduct of studies as part of the medical function in a global team.
  Understanding of the interplay between clinical development, research, manufacturing, commercial objectives and regulatory requirements.