text: But, getting there is a bumpy ride. One day the figure is less, the next day, it increases! And you are rendered depressed and frustrated. What went wrong? Did all your efforts go waste?
  The key however is to stay persistent and think less about the struggle. To make is less of a struggle, many supplements, shakes, tablets and drinks were introduced.
  If you have ever struggled to lose weight, Plexus slim can give you that much needed push. It comes in the form of a powder which should be mixed in water and that's about it! The drink is ready!
  It is 100% vegetarian, when drank, helps making you feel full and also regulates the blood sugar and cholesterol levels. Plexus slim was introduced in the year 2011 and contains a few key compounds- chromium, Garcinia cambogia, green coffee and alpha lipoic acid.
  2.Green coffee in Plexus slim helps lose weight
  3.Alpha Lipoic acid in Plexus Slim is good for weight loss
  4.Plexus Slim contains Garcinia cambogia that benefits in weight loss
  A review paper assessed the efficacy of chromium for weight loss in obese and overweight subjects. According 11 studies out of 20, chromium helped with the weight loss. However, in many studies, adverse effects were also observed such as headaches, vertigo and urticaria.
  Chromium can also be used in the treatment of diabetes. Since diabetes is inclusive of high blood sugar levels, it surfaces as a result of obesity. This is inclusive of high blood sugar levels, insulin resistance, low glucose sensitivity and a higher risk of heart diseases.
  A study was published in "BioFactors" in 2012, which reported that upon the administration of chromium picolinate for 4 weeks on animal model of diabetes, it lead to a decrease in plasma glucose levels, weight loss, a rise in the enzyme that break molecules of glucose and a decrease in the enzymes which form glucose molecules.
  In overweight individuals, chromium enhances the working of insulin and also lowers the risk of heart diseases.Chromium picolinate is the safest form of chromium and is absorbed the best by the body, the dosage varying between 200 and 1000mcg.
  A 6-month study was conducted on subjects suffering from binge eating disorder. They received chromium in the form of chromium picolinate. This lead to a reduction in fasting glucose, weight, binge frequency and symptoms of depression.
  A review paper addressed a few issues related to chromium intake. According to a few studies, there were 2 adverse effects observed in a group of subjects taking 1000microgram of chromium picolinate, and another adverse event occurred with a patient taking 400microgram of chromium picolinate.
  A study also resulted in no significant weight loss when overweight subjects incorporated 1000 micro grams of chromium picolinate into their diet for a period of 12 weeks.
  Chromium aids weight loss especially in the form of chromium picolinate. It also fights diabetes, insulin resistance and helps in controlling appetite.
  Green coffee is another ingredient that is present in Plexus slim. It has a compound called "chlorogenic acid" which imparts great benefits to coffee- such as helping with weight loss and diabetes.
  While green coffee is just the coffee seeds that are not roasted, chlorogenic acid content is lost if the coffee beans are roasted.
  An animal study published in "Asian Pacific journal of tropical medicine" 2016 reported that when green coffee bean extract reduced the body weight, as well as fat liver content and fat tissue. The hormones that are responsible for breaking down the fat were also regulated.
  Caffeine also promotes thermogenesis (production of heat in the human body) which helps burning calories and is useful in weight loss.
  A study was conducted on fasted subjects who consumed glucose along with some decaffeinated coffee. The chlorogenic acid decreased the absorption of glucose from the intestines. It hence had a regulatory effect of the transport on glucose.
  Subjects received a chewing gum containing green coffee extract, Garcinia cambogia and L-carnitine (an amino acid). Appetite sensations and food preferences were evaluated. Total calorie intake, sweet snack intake and hunger declined.
  Green coffee, being high in chlorogenic acid, helps in reduction of body weight, provides a good control over the appetite and also attenuates glucose intolerance.
  Obesity and high fat content in the body leads to inflammation. Due to this, a large number of free radicals are produced. These altogether rise in number and lead to a phenomenon called "oxidative stress".
  Alpha lipoic acid, being an antioxidant, fights oxidative stress and thereby helps in fighting diabetes and helping cholesterol levels to normalize.
  Hydroxycitric acid also helped in the reduction of visceral fat. Individuals were asked to consume a diet that consisting of Garcinia cambogia for a period of 12 weeks.
  The calcium/potassium salt of hydroxycitric acid is called Super CitriMax and is derived from the ring of the fruit of Garcinia cambogia. This salt benefits in type-2 diabetes, high levels of insulin resistance, inflammation and oxidative stress.
  The proteins involved in inflammation (such as interleukin-6 or C-Reactive protein) were reduced, so were the glucose, insulin and triglyceride levels. The appetite, food intake and weight also reduced. This overall lead to a lowering of oxidative stress.
  A hormone called "leptin" present in our body that leads to the feeling of "satiety". It works by the inhibiting hunger. In an animal study, upon the introduction to dietary Garcinia cambogia for a period of 4 weeks, a number of changes were observed.
  Insulin levels as well as leptin levels were loweredand it also improved glucose metabolism. This proved that Garcinia cambogia displays "leptin-like" activity.
  Garcinia cambogia, due to the presence of hydroxycitric acid, helps get rid of fat, whether it is visceral or subcutaneous. It attenuates insulin resistance, oxidative stress and also helps curb the appetite.
  With so many people trying to lose weight, there comes a saturation point, where all you need is a little push, a little help, a little motivation. That's when thermogenic aids or weight loss supplements come to play.