code: public static TetrahedralSign getHandedness(IAtom baseAtomA, IAtom baseAtomB, IAtom baseAtomC, IAtom apexAtom) {
          Point3d pointA = baseAtomA.getPoint3d();
          Point3d pointB = baseAtomB.getPoint3d();
          Point3d pointC = baseAtomC.getPoint3d();
          Point3d pointD = apexAtom.getPoint3d();
          return StereoTool.getHandedness(pointA, pointB, pointC, pointD);
      }
docs: Gets the tetrahedral handedness of four atoms - three of which form the
  'base' of the tetrahedron, and the other the apex. Note that it assumes
  a right-handed coordinate system, and that the points {A,B,C} are in
  a counter-clockwise order in the plane they share.
  
  @param baseAtomA the first atom in the base of the tetrahedron
  @param baseAtomB the second atom in the base of the tetrahedron
  @param baseAtomC the third atom in the base of the tetrahedron
  @param apexAtom the atom in the point of the tetrahedron
  @return the sign of the tetrahedron