code: def run(self, args=(), with_chroot=False, blocking=True, setsid=False, **kwargs):
      
      self.clean_environment()
  
      cmdline = self.cmdline(args)
      TRACER.log('PEX.run invoking %s' % ' '.join(cmdline))
      process = Executor.open_process(cmdline,
                                      cwd=self._pex if with_chroot else os.getcwd(),
                                      preexec_fn=os.setsid if setsid else None,
                                      stdin=kwargs.pop('stdin', None),
                                      stdout=kwargs.pop('stdout', None),
                                      stderr=kwargs.pop('stderr', None),
                                      **kwargs)
      return process.wait() if blocking else process
docs: Run the PythonEnvironment in an interpreter in a subprocess.
  
      :keyword args: Additional arguments to be passed to the application being invoked by the
        environment.
      :keyword with_chroot: Run with cwd set to the environment's working directory.
      :keyword blocking: If true, return the return code of the subprocess.
        If false, return the Popen object of the invoked subprocess.
      :keyword setsid: If true, run the PEX in a separate operating system session.
  
      Remaining keyword arguments are passed directly to subprocess.Popen.