code: def _prep_streamlined_config(config_script, work_dir):
      
      new_min_size = 100
      in_file = config_script + ".ini"
      out_file = os.path.join(work_dir, os.path.basename(in_file))
      with open(in_file) as in_handle:
          with open(out_file, "w") as out_handle:
              for line in in_handle:
                  if line.startswith("minCandidateVariantSize"):
                      out_handle.write("minCandidateVariantSize = %s\n" % new_min_size)
                  else:
                      out_handle.write(line)
      return out_file
docs: Create manta INI file without steps that potentially increase runtimes.
  
      This removes calling of small indels.