docs: def replace_vcf_info(keyword, annotation, variant_line=None, variant_dict=None):
      """Replace the information of a info field of a vcf variant line or a 
          variant dict.
      
      Arguments:
          variant_line (str): A vcf formatted variant line
          variant_dict (dict): A variant dictionary
          keyword (str): The info field key
          annotation (str): If the annotation is a key, value pair
                            this is the string that represents the value
      
      Returns:
          variant_line (str): A annotated variant line
      """
      new_info = '{0}={1}'.format(keyword, annotation)
      
      logger.debug("Replacing the variant information {0}".format(new_info))
      
      fixed_variant = None
      new_info_list = []
      
      if variant_line:
          logger.debug("Adding information to a variant line")
          splitted_variant = variant_line.rstrip('\n').split('\t')
          logger.debug("Adding information to splitted variant line")
          old_info = splitted_variant[7]
          if old_info == '.':
              new_info_string = new_info
          else:
              splitted_info_string = old_info.split(';')
              for info in splitted_info_string:
                  splitted_info_entry = info.split('=')
                  if splitted_info_entry[0] == keyword:
                      new_info_list.append(new_info)
                  else:
                      new_info_list.append(info)
              new_info_string = ';'.join(new_info_list)
          
          splitted_variant[7] = new_info_string
          
          fixed_variant = '\t'.join(splitted_variant)
      
      elif variant_dict:
          logger.debug("Adding information to a variant dict")
          old_info = variant_dict['INFO']
          
          if old_info == '.':
              variant_dict['INFO'] = new_info
          else:
              for info in old_info.split(';'):
                  splitted_info_entry = info.split('=')
                  if splitted_info_entry[0] == keyword:
                      new_info_list.append(new_info)
                  else:
                      new_info_list.append(info)
              new_info_string = ';'.join(new_info_list)
          
          variant_dict['INFO'] = new_info_string
          fixed_variant = variant_dict
      
      return fixed_variant