docs: def _is_normal_karyotype(karyotype):
          """
          This will default to true if no karyotype is provided.
          This is assuming human karyotypes.
          :param karyotype:
          :return:
          """
  
          is_normal = True
          if karyotype is not None:
              karyotype = karyotype.strip()
              if karyotype not in ['46;XX', '46;XY', '']:
                  is_normal = False
  
          return is_normal