Task: Determine the prevailing emotional tone of the tweet, categorizing it as either 'neutral or no emotion' or as one or more of the given emotions (anger, anticipation, disgust, fear, joy, love, optimism, pessimism, sadness, surprise, trust) that most accurately represent the tweeter's mental state.
Tweet: It’s possible changing meds is best not done while under stress. Difficult to tell what part of despair is circumstantial, what is drugs.
This tweet contains emotions: 
sadness