The researchers discovered that the number of alopecia-associated genes a person had correlated with the severity of the condition. Those who carried 16 or more genes (the genes are in pairs) were more likely to progress to alopecia universalis, or total hair loss. Researchers had expected that alopecia genes would be the same as those associated with other autoimmune diseases of the skin, such as psoriasis (in which the immune system signals the overproduction of skin cells, resulting in dry, scaly lesions) or vitiligo (loss of pigment to the skin when cells called melanocytes no longer function). Yet alopecia and psoriasis had only one of the eight genes in common, Christiano said.
ក្រុមអ្នកវិទ្យាសាស្ដ្ររកឃើញថា ភាពមិនប្រក្រតីកើតឡើងនៅពេលដែលអង់ហ្ស៊ីម ដែលគេស្គាល់ និងហៅថា “ glycine decarboxylase ” កើនឡើង វាអាចបង្កឱ្យមានការផ្លាស់ប្ដូរកោសិកា ដែលបញ្ហានេះបង្កឱ្យកើតមានរោគ មហារីកកើតឡើងតែម្ដង ។ ជាធម្មតា “glycine decarboxylase ” កើតឡើង ខណៈដែលអង់ហ្ស៊ីមនៅក្នុងកោសិកទាំងឡាយ ដោយមានបរិមាណ តិចតួចប៉ុណ្ណោះ ។