Below is an instruction that describes a task. Write a response that appropriately completes the request.

### Instruction:
With a 1st run of 53.300 (7), and greater than 21 total, what is the average rank?

### Inputs:
table_name: table, columns: ['Rank', 'Name', '1st run', '2nd run', '3rd run', 'Total']

### Response:
SELECT AVG Rank FROM table WHERE 1st run = 53.300 (7) AND Total > 21