Below is an instruction that describes a task. Write a response that appropriately completes the request.

### Instruction:
How many titles have directors of matthew Penn and number in series of 143?

### Inputs:
table_name: table, columns: ['No. in series', 'No. in season', 'Title', 'Directed by', 'Written by:', 'Original air date']

### Response:
SELECT COUNT Title FROM table WHERE Directed by = Matthew Penn AND No. in series = 143