The winners of the Knoxville Invitational were American players: Herman Keiser in 1946 with a score of 291 and Byron Nelson in 1944 with a score of 270 and of 276 in 1945.
The Knoxville Invitational was a golf tournament on the PGA Tour that was held in Knoxville, Tennessee from 1944 to 1946. The 1946 event was won by Herman Keiser. 1946 Herman Keiser 291 1945 Byron Nelson 276 1944 Byron Nelson 270 
