Phosphodiesterase type 1 has nine localizations, mostly cytosolic.
Predominantly cytosolic Predominantly cytosolic Predominantly cytosolic Cytosolic Cytosolic Cytosolic - Cytosolic - PDE1A () PDE1A1 PDE1A2 PDE1B1 () PDE1B2 PDE1C () PDE1C1 PDE1C2 PDE1C4/5 Most PDE1 isoforms are reported to be cytosolic. PDE1 (phosphodiesterase type 1) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. 
