How to Lose Friends & Alienate People stars Simon Pegg, Kirsten Dunst, Danny Huston, Gillian Anderson, Megan Fox and Jeff Bridges, alongside Max Minghella and Margo Stilley.
 In October 2017, Anderson appeared alongside Glenn Close and Christina Hendricks in Crooked House  a film adaptation of Agatha Christie's novel of the same name
 Her career progressed with a supporting role in Eternal Sunshine of the Spotless Mind (2004), followed by a lead role in Cameron Crowe's tragicomedy Elizabethtown (2005), and as the title character in Coppola's Marie Antoinette (2006)

