Vincenzo della Greca worked on the Castel Sant'Angelo in Rome and the design and construction of the church of San Caio in Rome is attributed to him
In 1623 he worked on the Castel Sant'Angelo in Rome as well as fortifications commissioned by Pope Urban VIII. In 1630, the design and construction of the church of San Caio in Rome is attributed to Della Greca; the church was demolished in 1885. 
