Holy Child College of Education was run by various principals since 1956 including Mother Mary Joachim and Mrs. Cecilia Harry Quaye.
Principals of the college since 1956 are: Mother Mary Joachim Mother Mary Colum Sister Kathleen Marine Sister Mary Anita Mrs. Lucy Peprah Tawiah Mrs. Mabel A. Ephraim - Acting Principal Miss Cecilia Pomary Mrs. Cecilia Harry Quaye 
