Horseshoe crabs are used in pesticides.
 This, combined with the acceptance of rFC by European regulators, the comparable cost between LAL and rFC, and support from Eli Lilly and Company, which has committed to use rFC in lieu of LAL, is projected to all but end the practice of blood harvesting from horseshoe crabs
 The earliest horseshoe crab fossils are found in strata from the Lower Ordovician period, roughly 480 million years ago

