MAPKAPK2 encodes a member of the Ser/Thr protein kinase family, and is regulated through direct phosphorylation by p38 MAP kinase (are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock).
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. 
