1922 Saint Louis Billikens football team (head coach Stephen G. O'Rourke) had five opponents between October 7 and November 30, one of which was Michigan State.
October 7 at Notre Dame at Grinnell Cumberland Missouri Missouri Mines Dallas South Dakota Loyola (LA) Michigan State October 14 October 21 October 28 November 4 November 11 November 18 November 25 November 30 
