A lack of sensory gating (referred to as gating or filtering) and a decline in working memory in the psychiatric disorder schizophrenia are called endophenotypes by having a clear genetic component.
Also referred to as gating or filtering, sensory gating prevents an overload of irrelevant information in the higher cortical centers of the brain. It is therefore more applicable to more heritable disorders, such as bipolar disorder and schizophrenia. In genetic epidemiology, endophenotype is a term used to separate behavioral symptoms into more stable phenotypes with a clear genetic connection. 
