James and the Giant Peach includes Richard Dreyfuss.
Co-stars Joanna Lumley and Miriam Margolyes played James 's aunts in the live-action segments , and Simon Callow , Richard Dreyfuss , Susan Sarandon , Jane Leeves , David Thewlis , and Margoyles voiced his insect friends in the animation sequences .	Simon Callow	Simon Callow	Richard Dreyfuss	Richard Dreyfuss	Jane Leeves	Jane Leeves	Joanna Lumley	Joanna Lumley	Miriam Margolyes	Miriam Margolyes	Susan Sarandon	Susan Sarandon	David Thewlis	David Thewlis
