On March 20, 2020,  Ezra Hendrickson signed a professional contract with USL club Seattle Sounders FC2, and made his debut the same day in a 4-2 victory over Sacramento Republic FC.
After retiring, Hendrickson joined the staff of Seattle Sounders FC, working as an assistant to his former coach, Sigi Schmid. After managing the Sounders reserves for several seasons, he was named head coach for Seattle Sounders FC 2 upon the club's entry into the United Soccer League. Seattle Sounders FC (assistant) Seattle Sounders FC 2 Saint Vincent and the Grenadines (assistant) LA Galaxy (assistant) Columbus Crew SC (assistant) 
