Mirtazapine is effective against projectile vomiting and nausea.
 As an H1 receptor antagonist, mirtazapine is extremely potent, and is in fact the most potent of all the tricyclic and tetracyclic antidepressants
 Unlike the tricyclic antidepressants, mirtazapine showed no significant cardiovascular adverse effects at 7 to 22 times the maximum recommended dose

