The western terminus of FM 1764 is at State Highway 146 (SH 146) in Santa Fe continuing to the north slightly and then east through farmland approximately 5.5 miles (8.9 km) towards junctions with FM 2004 and Interstate 45 (I-45) near Texas City.
The western terminus of FM 1764 is at State Highway 6 (SH 6) in Santa Fe. 
