Ctesiphon was a large city.
 Ctesiphon then continued to be involved in constant fighting between two factions of the Sasanian Empire, the Pahlav (Parthian) faction under the House of Ispahbudhan and the Parsig (Persian) faction under Piruz Khosrow
 In 197, the emperor Septimius Severus sacked Ctesiphon and carried off thousands of its inhabitants, whom he sold into slavery

