MUC-4  is involved in the progression of cancer and endometriosis (which causes infertitlity).
It is also found to play roles in other diseases such as endometriosis and inflammatory bowel disease. MUC-4 has been found to play various roles in the progression of cancer, particularly due to its signaling and anti-adhesive properties which contribute to tumor development and metastasis. The main symptoms are pelvic pain and infertility. 
