Thenuclearporecomplex(NPC)ismadeupofapproximatelythirtydifferentproteinsknownasnucleoporins,oneofwhich is the98kD which is producedviaabiogenesispathwaythatincludesthesynthesisandproteolyticcleavageofan186kDprecursorprotein.
The proteins that make up the nuclear pore complex are known as nucleoporins; each NPC contains at least 456 individual protein molecules and is composed of 34 distinct nucleoporin proteins.About half of the nucleoporins typically contain solenoid protein domainseither an alpha solenoid or a beta-propeller fold, or in some cases both as separate structural domains. 
