In the 201516 Campionato Sammarinese di Calcio, the top three teams from each group moved on to a play-off, which was played in a double elimination format with both group winners earning byes in the first and second round, and determined the season's champion.
The top three teams from each group advanced to a play-off which determined the season's champion and qualifiers for the 201617 UEFA Champions League and the 201617 UEFA Europa League. The play-offs were played in a double-eliminination format with both group winners earning byes in the first and second round. 
