RAD23B is a protein encoded by the RAD23B gene and is the  is the initial damage recognition factor in  global genomic nucleotide excision repair as well as the assembly of the other core NER factors
The presence of XPC-RAD23B is required for assembly of the other core NER factors and progression through the NER pathway both in vitro and in vivo. The complex of XPC-RAD23B is the initial damage recognition factor in global genomic nucleotide excision repair (GG-NER). UV excision repair protein RAD23 homolog B is a protein that in humans is encoded by the RAD23B gene. 
