The 1921 Saint Louis Billikens football team was an American football team that represented Saint Louis University during the 1921 college football season in their first season under head coach Stephen G. O'Rourke, the Billikens compiled a 4-4-1 record.
The 1921 Saint Louis Billikens football team was an American football team that represented Saint Louis University during the 1921 college football season. In their first season under head coach Stephen G. O'Rourke, the Billikens compiled a 441 record and was outscored by a total of 148 to 76. 
