Liver X receptor alpha is one of three liver X receptors, which activate thyroid hormones and play a role in regulating the expression of target genes.
Additionally, they play an important role in the local activation of thyroid hormones via deiodinases. The liver X receptor (LXR) is a member of the nuclear receptor family of transcription factors and is closely related to nuclear receptors such as the PPARs, FXR and RXR. 
