Hunan hand syndrome, first reported in he New England Journal of Medicine in 1981, is a painful cutaneous condition that can afflict those who handle chili peppers, which originated in Mexico.
Hunan hand syndrome (also known as "Chili burn") is a temporary, but very painful, cutaneous condition that commonly afflicts those who handle, prepare, or cook with fresh or roasted chili peppers. It was first described in an eponymous case report in the New England Journal of Medicine in 1981. Chili peppers originated in Mexico. 
