Sergio Santn made his official debut on July 18, 1980,  he represented his native country and played club football for Danubio which was founded by Bulgarian brothers.
Danubio was founded by the Bulgarian-born brothers Mihail (Miguel) and Ivan (Juan) Lazaroff on 1 March 1932 together with other youths from the "Republica de Nicaragua" school in Montevideo. Having made his official debut on July 18, 1980 against Peru (2-2), Santin obtained a total number of 18 international caps for the Uruguay national football team. He represented his native country at the 1986 FIFA World Cup, wearing the number eleven jersey. Santin played club football for Danubio and Penarol in Uruguay and Cucuta Deportivo, Atletico Nacional, Independiente Medellin and America de Cali in Colombia 
