The Charleston Southern Railway was established during the early 20th century, taking place following the attempts to merge the railroad with the Charleston Southern Railway, which was created in 1914 operating throughout the early 20th century.
The Charleston Southern merged with the Carolina, Atlantic and Western Railway in September 1915. The Charleston Southern Railway, incorporated by the South Carolina General Assembly in 1915, was to be an extension of the Seaboard Air Line Railroad, with an 85-mile route from Charleston, South Carolina, to Savannah, Georgia, planned. 
