Mirtazapine is commonly used as an antidepressant.
 As an H1 receptor antagonist, mirtazapine is extremely potent, and is in fact the most potent of all the tricyclic and tetracyclic antidepressants
== Pharmacology ===== Pharmacodynamics ===Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), although the actual evidence in support of this label has been regarded as poor

