Rose Mathews appeared as a weekly panelist on an American late night comedy talk show hosted by comedian Chelsea Handler which was broadcast on E!.
Are You There, Chelsea? was an NBC sitcom based on Handler's 2008 best-selling book Are You There, Vodka? It's Me, Chelsea, which aired from January 11 to March 28, 2012
 The Pepsodent Show, which opened each weekly episode with host Bob Hope's rapid-fire, topical and often political observational comedy, was a particularly important predecessor to the late-night format

