During diabetic ketoacidosis the body stores acidic ketone bodies.
, protonated ketones) are strong acids, with pKa values estimated to be somewhere between 5 and 7
 Although acids encountered in organic chemistry are seldom strong enough to fully protonate ketones, the formation of equilibrium concentrations of protonated ketones is nevertheless an important step in the mechanisms of many common organic reactions, like the formation of an acetal, for example

