Malaria is responsible for over 650,000 deaths annually, mainly in Africa; so in 2013, GSK applied for regulatory approval for the first malaria vaccine.
Malaria is a mosquito-borne infectious disease that affects humans and other animals. In 2018 there were 228 million cases of malaria worldwide resulting in an estimated 405,000 deaths. Approximately 93% of the cases and 94% of deaths occurred in Africa. 
