Foot Locker's headquarters are in Midtown Manhattan, New York City where they have operated for 25 years.
 Seven of the world's top eight global advertising agency networks have their headquarters in New York
 By mid-2014, Accelerator, a biotech investment firm, had raised more than $30 million from investors, including Eli Lilly and Company, Pfizer, and Johnson & Johnson, for initial funding to create biotechnology startups at the Alexandria Center for Life Science, which encompasses more than 700,000 square feet (65,000 m2) on East 29th Street and promotes collaboration among scientists and entrepreneurs at the center and with nearby academic, medical, and research institutions

