Paracetamol may be used in lower doses in those with kidney disease.
 Paracetamol is particularly dangerous to the liver in overdose, but even without overdose those who take this drug may develop acute liver failure requiring liver transplantation more frequently than the users of nonsteroidal anti-inflammatory drugs
=== Pharmacokinetics ===After being taken by mouth, paracetamol is rapidly absorbed from the small intestine, while absorption from the stomach is negligible

