Mutations with the Ryanodine receptor 2 is linked to catecholaminergic polymorphic ventricular tachycardia which functions in the myocardium.
Mutations in the RYR2 gene are associated with catecholaminergic polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. Normal (wild type) RyR2 functions primarily in the myocardium (heart muscle). 
