The 1965 Clemson Tigers football team defeated the 1965 NC State Wolfpack football team, led by 12th-year head coach Earle Edwards, by 21-7 on September 18.
September 18 NC State W 217 The Wolfpack were led by 12th-year head coach Earle Edwards and played their home games at Riddick Stadium for the last time before moving to Carter Stadium. 
September 18 at Clemson L 721 The Wolfpack were led by 12th-year head coach Earle Edwards and played their home games at Riddick Stadium for the last time before moving to Carter Stadium. 
