The 1917 Saint Louis Billikens football team was under coach Charles M. Rademacher (who played college football at the University of Chicago under head coach Amos Alonzo Stagg) that competed against Cape Girardeau Normal in their opening game with a score of 34-0, but then dropped their next three games against Indiana, Drury, and DePauw.
In their first and only season under head coach Charles M. Rademacher, the Billikens compiled a 431 record and outscored opponents by a total of 79 to 61. Rademacher played college football at the University of Chicago under head coach Amos Alonzo Stagg, serving as team captain in 1911. October 6 Cape Girardeau Normal W 340 L 040 L 07 L 014 at Indiana Drury DePauw October 13 October 20 October 27 
