The Great Boston fire of 1760, which took place in Boston destroying 349 buildings went through Water Street and Milk Street before advancing to Fort Hill.
The Great Boston fire of 1760 was a major conflagration that occurred on March 20, 1760, in downtown Boston. The fire destroyed 349 buildings in the area between the modern Washington Street and Fort Hill as well as several ships in port, and left over a thousand people homeless. On its southeastern side, the fire expanded from Water Street to Milk Street, where it consumed many of the houses to both the west and east. From there it advanced via Batterymarch to Fort Hill, taking most of the buildings along the way, and reached the South Battery. 
