Hand, foot, and mouth disease can occur in the rainforest.
 Indeed, genes specifically expressed in the dermis of palmoplantar skin inhibit melanin production and thus the ability to tan, and promote the thickening of the stratum lucidum and stratum corneum layers of the epidermis
There are numerous sesamoid bones in the hand, small ossified nodes embedded in tendons; the exact number varies between people: whereas a pair of sesamoid bones are found at virtually all thumb metacarpophalangeal joints, sesamoid bones are also common at the interphalangeal joint of the thumb (72

