DLG1 is associated with Chron's Disease as the n-terminal of SAP97 can be alternatively spliced to contain a double-cysteine/palmitoylation site.
Mutations in DLG1 are associated to Crohn's Disease. The n-terminal of SAP97 can be alternatively spliced to contain a double-cysteine/palmitoylation site (-isoform), or an L27 domain (-isoform. 
