Catherine Keener appeared in Into the Wild.
In 2005, she starred in the political thriller The Interpreter (as a Secret Service agent partnered with Sean Penn's character) and The Ballad of Jack and Rose with Daniel Day-Lewis, and played the love interest of Steve Carell in Judd Apatow's The 40-Year-Old Virgin
Keener's sister, Elizabeth Keener, is also an actress and a real estate agent working for Sotheby's in Los Angeles

