Atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants, and some of the drugs classified as an atypical antidepressant are agomelatine and bupropion.
An atypical antidepressant is any antidepressant medication that acts in an manner that is different from that of most other antidepressants. Atypical antidepressants include agomelatine, bupropion, mianserin, mirtazapine, nefazodone, opipramol, tianeptine, and trazodone. 
