Some major roads which are parallel to the Ohio State Route 169, a state highway which was created in 1923, are US 422 at Weathersfield Township and SR 46 north at Niles.
US 422 (Youngstown-Warren Road) / Tibbets Wick Road  Girard, Youngstown Weathersfield Township 
SR 46 north (Vienna Avenue) / Mahoning Avenue SE Niles 
