The highway, which passes through Ozark Highlands, an American Viticultural Area which was established in 1987, Fourche River, Highway 166 and the Current River, is called Arkansas HIghway 328.
The highway runs northeast through sparsely populated areas of the Ozark Highlands and crossing Fourche River. The Ozark Highlands AVA is an American Viticultural Area located in southern Missouri in the Ozark Mountains. 1987 Highway 166 and Highway 328 briefly concur eastward through Maynard before the former turns northward. Highway 328 continues easterly, crossing into the flatter terrain of the Mississippi Alluvial Plain before turning due south as a section line road, crossing the Current River, and running to Reyno. 
