Keys ni a co-founder ati Global Ambassador of Keep a Child Alive, a non-profit organization that provides medicine, orphan care, and social support to families with HIV and AIDS in Africa and India. Keys ni a bi nigba kan nigba ti AIDS ajakalẹ arun ti won gaining a pupo ti ifojusi ni United States. O ti akọkọ ti ni ipa nipasẹ awọn HIV / AIDs idaamu ni 8 years atijọ nigbati iya rẹ ká ọrẹ kú lati arun. O ti ri akọkọ-ọwọ awọn gbooro ti ipa ti AIDS ajakalẹ arun years nigbamii lori a ibewo si South Africa, a irin ajo ti o je awọn impetus to cofounding Keep a Child Alive. Keys ti ṣe ọrẹ AIDS activist Leigh Blake, ti o ti de jade lati ran o si mu rẹ imo si awọn agbaye ti HIV / AIDS. Black Keys ati South African Black Keys ibewo pẹlu HIV-onigbọwọ iya ati awọn ọmọ, ati awọn Keys ni a gbajumo ni ayika awọn orilẹ-ede miiran, pẹlu awọn oniwe-ara ti o ti waye ni ayika 2014.
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