A ti ṣe idanimọ aisan Alzheimer gẹgẹbi aisan protein misfolding (proteopathy), ti o fa nipasẹ ikojọpọ plaque ti amulet beta amyloid ati amulet protein amulet ninu ọpọlọ. Awọn plaques ti wa ni awọn peptide kekere, 39<unk>43 amino acids ni ipari, ti a npe ni amulet beta (Aβ). Aβ jẹ apakan lati amulet amulet precursor protein (APP) ti o tobi julọ. APP jẹ amulet transmembrane ti o wọle nipasẹ awọ ti neuron. APP jẹ pataki si idagba neuron, iwalaaye, ati atunṣe lẹhin-ipalara. Ni aisan Alzheimer, gamma secretase ati beta secretase ṣiṣẹ papọ ni ilana amulet eyiti APP ti pin si awọn ẹya kekere. Ọkan ninu awọn ẹya wọnyi n funni ni awọn iṣiro ti amulet beta amyloid, eyiti o jẹ iṣiro ti amulet ti o wa ni ita ti amulet ti a npe ni amulet beta (Aβ).
protein tí ó so mọ́ microtubule