Ioan Gruffudd bi Reed Richards / Mr. Fantastic, Jessica Alba bi Sue Storm / Invisible Woman, Chris Evans bi Johnny Storm / Human Torch, ati Michael Chiklis bi Ben Grimm / The Thing pada bi The Fantastic Four, nigba ti Julian McMahon ati Kerry Washington tun ṣe ipa wọn lati fiimu akọkọ bi Victor von Doom / Doctor Doom ati Alicia Masters, lẹsẹsẹ. Beau Raye bi Frankie Raye, pẹlu Doug Norrin bi Radd / Silver, pẹlu Laurence Fishburne Surfer Silver.
Ọdún 2007