Kofeini tun le wa ni gba nipasẹ rectally, evidenced nipa suppositories ti ergotamine tartrate ati caffeine (fun imukuro ti migraine) ati chlorobutanol ati caffeine (fun itọju ti hyperemesis). Sibẹsibẹ, rectal absorption jẹ kere munadoko ju ẹnu: awọn ti o pọju idojukọ (Cmax) ati lapapọ gba iye (AUC) jẹ mejeji nipa 30% (i.e., 1/3.5) ti awọn ti ẹnu iye.Caffeine ká biological idaji aye <unk> awọn akoko ti o nilo fun awọn ara lati yọ ọkan-aaya-aaya-aaya ti kọọkan wakati yatọ laarin 1<unk>2 wakati. O ti wa ni kuro nipa akọkọ-ọya kinetics. Caffeine le tun wa ni gba nipasẹ rectally, evidenced nipa suppositories ti ergotamine tartrate ati caffeine (fun imukuro ti migraine) ati chlorobutanol ati caffeine (fun itọju ti hyperemesis). Sibẹsibẹ, rectal absorption jẹ kere munadoko ju ẹnu: awọn ti o pọju ifojusi (Cmax) ati lapapọ gba iye (AUC) ni o wa
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