Amfani da acid acetic a cikin alchemy ya faɗaɗa zuwa ƙarni na 3 kafin haihuwar Yesu, lokacin da masanin falsafa na Girka Theophrastus ya bayyana yadda vinegar ke aiki a kan karafa don samar da launuka masu amfani a cikin fasaha, gami da fararen gubar (lead carbonate) da verdigris, cakuda kore na gishirin jan karfe gami da jan ƙarfe (((II) acetate. Tsoffin Romawa sun tafasa ruwan inabi mai ɗaci don samar da syrup mai daɗi mai suna sapa. Sapa da aka samar a cikin tukwane na gubar yana da wadataccen gubar a cikin acetate, wani abu mai daɗi wanda ake kira sukari na gubar ko sukari na Saturn, wanda ya ba da gudummawa ga guba mai guba a tsakanin masarautar Romawa. A cikin karni na 16, masanin kimiyyar Jamus Andreas Libavius ya yi imanin cewa sun bayyana irin wannan kaddarorin na acid acetic daga samar da sinadarin acetate mai bushe a cikin ruwan inabi da ruwan inabi.
Vinegar (abin da ake kira vinegar)