Rubuta ci gaba don wannan sakin layi - A cikin postseason, Ramirez ya buga wasan gida-gida uku a cikin kasa na tara na wasan na biyu na gasar zakarun Amurka da Los Angeles Angels na Anaheim, ya karya 3-3 a lokacin da ya kaddamar da kwallon a kan Fenway Park's Monster kujeru bayan bangon hagu na filin. A cikin wasan na huɗu na wasan karshe na jerin, Ramirez ya haɗu tare da abokin aikinsa David Ortiz don buga gida-gida a baya-baya daga jaririn Jered Weaver. Gidan gida ya raba shi tare da Bernie Williams a matsayin na farko a duk lokacin da aka buga wasanni na gida tare da 22. Red Sox sun ci gaba zuwa 2007 American League Championship Series
a kan Cleveland Indians inda, a ranar 13 ga Oktoba, Ramirez ya buga wasan sa na 23 a cikin wasan, ya wuce Williams don mafi yawan lokaci. Ya taimaka wa Red Sox don kaiwa da lashe gasar cin kofin duniya ta 2007, inda suka share Colorado Rockies, ta hanyar buga haɗin.348 tare da gida huɗu da 16 RBI a cikin postseason. Ramirez ya sami zobe na biyu na gasar cin kofin duniya, yayin da Red Sox suka sami taken su na bakwai.