Ka kammala wannan magana: A shekara ta 1854, cutar kwalara ta kashe kashi 5.5 na yawan mutanen Chicago (kusan mutane 3,500). Providence, Rhode Island ta fuskanci annoba da ta bazu sosai har shekaru talatin da suka biyo baya, an san shekara ta 1854 a can da "Shekarar Kwalara". A shekara ta 1853 zuwa 1854, annobar ta yi sanadiyar mutuwar mutane 10,739 a Landan. Ƙungiyar
1854 Cutar cutar kwalara ta Broad Street a London ta ƙare bayan likitan John Snow ya gano wani fanfo na unguwar Broad Street a matsayin gurbatacce kuma ya shawo kan jami'ai su cire makullin don hana mutane jan ruwa a can. Binciken da ya yi ya nuna cewa gurɓataccen ruwa shi ne ainihin abin da ke yaɗa cutar kwalara, ko da yake bai gano abin da ya gurɓata ba. Zai ɗauki shekaru da yawa kafin mutane su gaskata da wannan saƙon kuma su aikata daidai da shi. A Spain, fiye da mutane 236,000 ne suka mutu sanadiyyar cutar kwalara a shekara ta 1854 zuwa 1855. Cutar ta kai Kudancin Amurka a shekara ta 1854 da 1855, tare da wadanda suka mutu a Venezuela da Brazil. A lokacin annoba ta uku, mazauna Tunisia, wadanda annoba biyu da suka gabata ba su shafe su ba, sun yi tunanin Turawa ne suka kawo cutar. Sun ɗora laifin a kan hanyoyin tsabtace su. Wasu masana kimiyyar Amurka sun fara yin imani da cewa cutar kwalara ta haɗu da Ba'amurke Ba'amurke, kamar yadda cutar ta kasance a cikin Kudu a yankunan da baƙar fata ke zaune. Masu bincike na yanzu sun lura da yawan jama'arsu ba su da wadataccen kayan aikin tsaftacewa da kiwon lafiya, kuma suna zaune kusa da hanyoyin ruwa ta hanyar da matafiya da jiragen ruwa ke dauke da cutar.