Cika wannan jumla: Na farko na
Yaƙe-yaƙe na Anglo-Powhatan ya faru daga 1610 zuwa 1614, farawa bayan wani hari daga mazauna Virginia sun kashe dubun-dubatar Powhatan. A shekara ta 1622, Yaƙin Anglo-Powhatan na biyu ya ɓarke lokacin da Powhatan ya kai hari kan Jamestown kuma ya kashe mazauna 347, kusan kashi 30% na mazaunan ƙauyen a lokacin. A shekara ta 1644, Powhatan ya kai hari kan Jamestown a daidai wannan hanyar da aka kai hari a 1622. Sun kashe mazauna 400, kimanin kashi 10% na jama'ar Jamestown a lokacin, wanda ya fara yakin Anglo-Powhatan na uku.