Cika wannan jumla: A wasan karshe na shekara ta 2005, Pierzynski ya kasance babban dan wasa ga White Sox. A wasan farko na ALDS da Red Sox mai karewa, Pierzynski zai fara White Sox da karfi tare da wasan homerun 3 a wasan farko na Matt Clement. Zai kara na biyu a gida a kasa na 8th a kan Bronson Arroyo don taimakawa jagorancin White Sox zuwa nasara mai nasara 14-2. Pierzynski ya gama wasan 3<unk>3 tare da RBIs 4. Pierzynski kuma ya buga sau biyu kuma ya zira kwallaye na inshora a saman wasan na 9th yayin da White Sox ya ci Red Sox 5<unk>3 don tabbatar da jerin kuma ya ci gaba zuwa
ALCS. Abin da ya sa? Wataƙila wasan da Pierzynski ya fi girma, kuma mafi sanannun wasa, ya zo ne a Game 2 na ALCS a kan Los Angeles Angels na Anaheim. A baya 0<unk>1 a cikin jerin kuma wasan ya daidaita a 1<unk>1 a kasan 9th inning, Pierzynski ya shahara sosai a kan ƙwallon ƙasa a cikin datti daga Kelvim Escobar. Tunanin sun gama wasan, Mala'iku sun ci gaba da tafiya daga filin; duk da haka, lura da cewa alkalin wasa na gida Doug Eddings bai yi kira ba, Pierzynski ya gudu zuwa layin farko kuma an kira shi lafiya. Mai karɓar mala'iku Josh Paul da manajan Mike Scioscia sun yi jayayya da Eddings amma kiran ya tsaya, kuma an maye gurbin Pierzynski da Pablo Ozuna, wanda ya saci na biyu. Joe Crede zai ƙare wasan a kan tafiya-off biyu don daidaita jerin a 1-1. White Sox ba su sake yin nasara ba, sun lashe wasanni 3 na gaba a Anaheim don ci gaba zuwa gasar cin kofin duniya ta farko tun 1959. White Sox za su shafe Houston Astros don lashe gasar zakarunsu ta farko a cikin shekaru 88, suna ba Pierzynski zobensa na farko. Pierzynski ya buga.262 tare da 3 gida gudu da kuma 9 RBI, kama duk 11 wasanni ga White Sox a lokacin da suka yi gasar.