Kammala wannan jumla: A cikin 'yan Republican na 2016 na farko, Estrosi ya kuma goyi bayan Sarkozy a matsayin dan takarar jam'iyyar don zaben shugaban kasar Faransa na 2017. Watanni goma kafin zaben, shi da sauran masu ra'ayin mazan jiya na gida sun soki ministan cikin gida Bernard Cazeneuve saboda karfin rundunar 'yan sandan kasa a daren da aka yi zaben.
Harin da aka kai da babbar mota a shekara ta 2016. A tsakiyar al'amarin Fillon, a cikin Maris 2017, Estrosi ya shiga Xavier Bertrand, Valérie Pécresse da sauransu don kiran Alain Juppé ya maye gurbin François Fillon a matsayin dan takarar jam'iyyar. Har ila yau, ya sadu da Emmanuel Macron a lokacin yakin neman zabensa.