Ka cika wannan magana: An haifi Fabrizio kafin shekara ta 1452. Ya auri Agnese da Montefeltro 'yar Federico da Montefeltro, 1st Duke na Urbino, da kuma Battista Sforza. An san Fabrizio a matsayin mai suna Tagliacozzo da kuma babban jami'in mulkin Naples. A lokacin yakin Italiya na 1499<unk>1504, ya taka muhimmiyar rawa a cikin
Yaƙin Cerignola a shekara ta 1503. Ya kasance janar a cikin Holy League wanda ya yi yaƙi da Louis XII na Faransa daga 1509 zuwa 1515, kuma a yakin Ravenna, ya umurci sojojin Papal States da Faransa.