Kammala jumla mai zuwa: An dakatar da manufar Suleiman I na fadadawa a duk fadin tekun Bahar Rum a Malta a 1565. A lokacin kewayewar bazara wanda daga baya za a san shi da Siege of Malta, sojojin Ottoman wadanda suka kai kimanin 50,000 sun yi yaƙi da Knights of St. John da garkuwar Maltese na maza 6,000. Tsananin juriya ta Maltese ya haifar da ɗagawar kewaye a watan Satumba. Rashin nasarar kewaye (Turai sun sami nasarar kama tsibirin Gozo tare da Fort Saint Elmo a babban tsibirin Malta, amma sun kasa a wani wuri kuma sun ja da baya) shi ne karo na biyu da na karshe da Suleiman Mai Girma ya sha wahala bayan irin wannan rashin nasara.
na farko da Ottoman kewaye Vienna a 1529. Suleiman I ya mutu ne daga cututtukan halitta a cikin tantinsa yayin kewaye da Szigetvár a 1566. Yaƙin Lepanto a shekara ta 1571 (wanda ya haifar da kamawar Ottoman na tsibirin Cyprus da Venetian ke sarrafawa a shekara ta 1570) wani babban koma baya ne ga rinjaye na Ottoman a cikin Bahar Rum, duk da cewa an gina babban jirgin ruwan Ottoman a cikin ɗan gajeren lokaci kuma an dawo da Tunisia daga Spain a 1574.