Ka cika wannan jumla: A London a watan Yuni na shekara ta 1866, wata annoba da ta bazu a yankin East End ta kashe mutane 5,596, a daidai lokacin da birnin yake kammala gina manyan hanyoyin da ke kula da najasa da kuma ruwan sha (duba tsarin magudanar ruwa na London); Ba a kammala sashen East End ba. Masanin cututtukan cututtuka William Farr ya gano Kamfanin Ruwa na Gabashin London a matsayin tushen gurbatawa. Farr ya yi amfani da aikin da John Snow da sauransu suka yi a baya wanda ke nuna gurɓataccen ruwan sha a matsayin dalilin cutar kwalara a cikin wani
1854 fashewa. Matakin da aka ɗauka da sauri ya hana ƙarin mutuwar mutane. A cikin wannan shekarar, amfani da gurbataccen ruwan canal a ayyukan ruwa na gida ya haifar da karamin barkewar cutar a Ystalyfera a Kudancin Wales. Ma'aikatan kamfanin da iyalansu ne suka fi shan wahala, kuma mutane 119 ne suka mutu.