Kammala wannan jumla: A watan Janairun 2011, Mattek-Sands ta samu nasara mafi girma a cikin aikinta ta hanyar kayar da duniya mai lamba 7, Francesca Schiavone. Daga baya Mattek-Sands ya haɗu da John Isner don Amurka kuma ya kai Kofin Hopman
karshe, ta doke tawagar 'yan Belgium na Justine Henin da Ruben Bemelmans.