Ka cika wannan jumla: Farin tsakiyar Mexico ya jawo ƙarin mamayar Spain, bin tsarin yankuna da aka ci nasara da kuma ƙarfafawa ya zama wurin farawa don ƙarin tafiye-tafiye. Wadannan sau da yawa shugabannin na biyu ne ke jagorantar su, kamar Pedro de Alvarado. Nasarar da aka yi a Mexico daga baya yaƙe-yaƙe ne na dogon lokaci da ba su da sakamako mai ban mamaki kamar na Aztecs. Mutanen Espanya sun ci Yucatán, da
Nasarar Mutanen Espanya na Guatemala, nasarar Tarascans / Purépecha na Michoacan, yaƙin yammacin Mexico, da Chichimeca War a arewacin Mexico sun faɗaɗa ikon Mutanen Espanya a kan ƙasa da 'yan asalin ƙasar. Amma sai lokacin da Mutanen Espanya suka ci ƙasar Peru ne mutanen Aztec suka ci ƙasar da yaƙi, kuma hakan ya kai ga cin nasara a kan daular Inca a shekara ta 1532.