Kammala wannan jumla: A ranar 23 ga Afrilu, a kan Mala'iku, Teixeira ya shiga cikin haɗarin gida da Bobby Wilson yayin da yake zamewa gida. Teixeira ya yarda cewa karo ba da gangan ba ne, kuma ƙungiyar ba ta hukunta shi ba saboda aikinsa. A ranar 8 ga Mayu, Teixeira ya zama dan wasan Yankees na biyu da ya buga gida uku a cikin wasa daya da Boston Red Sox, tare da Lou Gehrig, wanda ya kammala aikin a ranar 23 ga Yuni, 1927. A ranar 20 ga Yuni, a kan New York Mets, Teixeira ya buga babbar nasara a kan Johan Santana, yana tabbatar da cewa Yankees ne kawai suka yi laifi a wasan a cikin nasarar 4-0. Bugu da ƙari, Teixeira ya lashe lambar yabo ta Golden Glove ta 2010 don 'yan wasan farko na Amurka. A cikin wasanni 158 na 2010, Teixeira ya gama da matsakaicin.256, 33 home runs, da 108 runs batted in. Ya kuma jagoranci gasar zakarun Amurka tare da zira kwallaye 113. A cikin
2010 ALCS, Teixeira ya ji rauni a cikin hamstring, kuma bai yi wasa ba don sauran wasan kwaikwayo. Yankees sun rasa jerin zuwa Rangers a wasanni shida.