Kammala jumla mai zuwa: PA 441 ya haye Conewago Creek zuwa Londonderry Township a Dauphin County kuma ya ci gaba zuwa arewa tsakanin gonaki da wasu gandun daji zuwa gabas da Norfolk Southern Royalton Branch da kogin Susquehanna zuwa yamma. Hanyar tana wucewa zuwa gabashin Tsibirin Three Mile, wanda shine wurin tsohon tashar samar da makamashin nukiliya ta Tsibirin Three Mile, wurin da aka gina wani
wani ɓarkewar nukiliya a shekarar 1979. Bayan tsohuwar tashar wutar lantarki ta nukiliya, hanyar ta lanƙwasa arewa maso yamma sannan kuma arewa yayin da take wucewa ta cikin yankunan da ke da gidaje tare da kogin da layin dogo zuwa yammacin hanyar. PA 441 ya ƙetare Royalton Branch a-grade kuma ya shiga gundumar Royalton, yana zuwa arewa maso yamma ta yankunan zama tare da Canal Street. Hanyar ta zama daidai da Amtrak's Keystone Corridor zuwa gabas kuma ta ƙetare Swatara Creek zuwa gundumar Middletown. A nan, PA 441 ya bi Ann Street arewa maso yamma kafin ya juya arewa zuwa South Union Street, tare da PA 441 Truck yana ci gaba tare da Ann Street. Hanyar tana wucewa ta kasuwanci kuma ta wuce ƙarƙashin Norfolk Southern's Royalton Branch da Amtrak's Keystone Corridor kusa da tashar Middletown. Hanyar tana jagorantar ta hanyar kasuwanci a cikin gari, ta ƙetare Middletown da Hummelstown Railroad, wanda ke tafiya tare da Brown Street, a matakin kafin ya ƙetare titin Emaus kuma ya ci gaba zuwa yankunan zama tare da titin Union Street. PA 441 ya juya zuwa arewa maso yamma kuma ya zo a wani kusurwa tare da PA 230, inda PA 441 Truck ya dawo zuwa hanya. Hanyar ta wuce gidaje da yawa kuma tana zuwa gabashin makabarta, ta zama iyaka tsakanin Lower Swatara Township zuwa yamma da gundumar Middletown zuwa gabas yayin da take ci gaba zuwa arewa kuma ta zo gada a kan Pennsylvania Turnpike (I-76).