Rubuta ci gaba don wannan sakin layi - Unser ya fara IndyCar a 1962 (ban da tseren Pikes Peak wanda ya kasance wani ɓangare na lokacin IndyCar a cikin 1950s). Ya yi tsere don Andy Granatelli tsakanin 1963 da 1965 tare da injin Novi. Unser ya fara tsere a Indianapolis 500 a shekarar 1963. Ya fadi da wuri kuma ya sanya 33rd. Unser na biyu Indianapolis 500 a shekarar 1964
ya ƙare a zagaye na biyu a cikin hadarin da ya kashe Eddie Sachs da Dave MacDonald. Unser ya koma IndyCar mallakar Bob Willke daga 1966 zuwa 1970. Gasar IndyCar ta farko ta zo ne a shekarar 1967 a Mosport, a Ontario. Bayan shekara guda, Unser ya lashe Indianapolis 500 na farko, ya kafa tarihi a matsayin direba na farko da ya yi tsere fiye da mil 170 a awa daya a Indianapolis. A cikin 1968, Unser ya yi aiki tare da shugaban ma'aikata Jud Phillips kuma ya lashe gasar cin kofin USAC ta farko tare da nasara a Stardust International Raceway, Phoenix Raceway, Trenton Speedway, Indy, da Pikes Peak Hill Climb.