Ka cika wannan jumla: Wilson ya nemi dangantaka ta kusa da Latin Amirka, kuma yana fatan ya kafa ƙungiyar 'yan Amirka don yin sulhu a tsakanin ƙasashen duniya. Ya kuma tattauna yarjejeniya tare da Colombia wanda zai biya wannan kasar diyya ga rawar da Amurka ta taka a cikin rabuwa da Panama, amma Majalisar Dattawa ta ci wannan yarjejeniyar. Duk da haka, Wilson sau da yawa ya shiga cikin al'amuran Latin Amurka, yana cewa a 1913: "Zan koya wa jamhuriyoyin Kudancin Amirka su zabi mutanen kirki". Jamhuriyar Dominica ta kasance mai karewa ta Amurka tun lokacin shugabancin Roosevelt, amma ta sha wahala daga rashin kwanciyar hankali. A shekara ta 1916, Wilson ya aika da sojoji don su mallaki tsibirin, kuma sojojin sun kasance har zuwa 1924. A shekara ta 1915, Amurka
sun shiga tsakani a Haiti bayan wani tawaye ya kifar da gwamnati, mamayar ta ci gaba har zuwa 1919. Wilson kuma ya ba da izinin shiga tsakani na soja a Cuba, Panama, da Honduras. Yarjejeniyar Bryan-Chamorro ta 1914 ta mai da Nicaragua ta zama wata kariya ta gaskiya, kuma Amurka ta sanya sojoji a can a duk lokacin shugabancin Wilson.