Kamar sauran tsakiyar da kudancin Appalachia, Appalachian Ohio ya mallaki masu mallakar masana'antu a cikin shekarun 1800 da kuma mafi yawan shekarun 1900.
Tabbas, wani nau'i mai rikitarwa na jumla shine "Kamar sauran tsakiyar da kudancin Appalachia, Appalachian Ohio an sarrafa shi ta hanyar masana'antun da ba su kasance ba a ƙarshen 1800s da kuma mafi yawan 1900s, kuma a yau yana da yawa daga al'adun al'adu, siyasa, da kuma matsalolin muhalli na gabashin Kentucky da West Virginia. "