Kammala jumla mai zuwa: Yayin da Messi ya haɓaka zuwa haɗuwa da lamba 8 (mai halitta), 9 (mai zira kwallaye), da 10 (mataimaki), ya ci kwallaye 73 da ba a taɓa gani ba kuma ya ba da taimako 29 a duk gasa na kulob a lokacin kakar 2011-12, yana samar da hat-trick ko fiye a lokuta 10. Ya fara kamfen din ne ta hanyar taimakawa Barcelona ta lashe kofin Mutanen Espanya da na Turai.
Kofin Zakarun Turai; a Supercopa de España, ya ci sau uku don cimma nasarar 5<unk>4 a kan Real Madrid, inda ya wuce Raúl a matsayin mafi yawan 'yan wasan gasar tare da kwallaye takwas. A ƙarshen shekara, a ranar 18 ga Disamba, ya zira kwallaye biyu a wasan karshe na gasar cin kofin duniya ta FIFA, nasara 4-0 a kan Santos, inda ya sami lambar yabo ta Golden Ball a matsayin mafi kyawun ɗan wasan gasar, kamar yadda ya yi shekaru biyu da suka gabata. Don kokarinsa a shekara ta 2011, ya sake karɓar FIFA Ballon d'Or, ya zama ɗan wasa na huɗu a tarihi don lashe Ballon d'Or sau uku, bayan Johan Cruyff, Michel Platini, da Marco van Basten. Bugu da kari, ya lashe kyautar UEFA Mafi Kyawun Playeran wasa a Turai, farfado da tsohuwar Ballon d'Or. A lokacin, an riga an dauki Messi a matsayin daya daga cikin 'yan wasan kwallon kafa mafi kyau a tarihi, tare da' yan wasa kamar Diego Maradona da Pelé.