Rubuta ci gaba don wannan sakin layi - Kodayake wasan farko da aka yi rikodin ta wani bangare na Uruguay an buga shi a ranar 16 ga Mayu 1901 da Argentina, wannan ba a dauke shi a matsayin wasan hukuma ba saboda ba kungiyar kwallon kafa ta Uruguay ce ta shirya wasan ba amma ta Albion F.C. a filin wasan ta a Paso del Molino. Bangaren Uruguay yana da 'yan wasa tara daga wannan kulob din kuma sauran daga Nacional. Wasan da aka yi la'akari da wasan farko na Uruguay da aka buga a wannan wurin, a ranar 20 ga Yuli 1902 da Argentina. Argentina ta doke kungiyar Uruguay da ci 6-0 a gaban 'yan kallo 8,000. Uruguay line-up ya kasance: Enrique Sardeson; Carlos Carve Urioste, Germán Arímalo; Miguel Nebel (c), Alberto Peixoto, Luis Carbone; Bolívar Céspedes, Gonzalo Rincón, Juan Sardeson, Ernesto Boutón Reyes, Carlos Céspedes. A cikin jerin sunayen da aka buga a gasar, sun hada da: Enrique Sardeson, Carlos Carve Urioste, Germán Arímalo; Miguel Nebel (c), Alberto Peixoto, Luis Carbone; Bolívar Céspedes, Gonzalo Rincón, Juan Sardeson, Ernesto Boutón Reyes, Carlos Céspedes. Kafin 1916, Uruguay ta buga wasanni sama da 30, wanda duka sai daya ne da Argentina. Gasar Copa America ta farko
Uruguay ta ba da 'yan adawa daban-daban. Nasara a kan Chile da Brazil, tare da wasa da Argentina, ya ba Uruguay damar lashe gasar. A shekara mai zuwa Uruguay ta karbi bakuncin gasar, kuma ta riƙe taken ta hanyar lashe kowane wasa. Copa América ta 1919 ta ga Uruguay ta fara shan kashi a gasar, rashin nasara 1<unk>0 a wasan da aka yi da Brazil wanda ya tafi tsawon lokaci biyu, wasan da ya fi tsayi a Copa América a tarihi.