Rubuta ci gaba don wannan sakin layi - A cikin ƙarni na 16 da 17, an gina kariya mai zagaye uku: Kitay-gorod (Китай-город), White City (Белый город) da Earthen City (Земляной город). Amma, a shekara ta 1547, gobara guda biyu ta halaka yawancin birnin, kuma a shekara ta 1571 'yan Tatar da ke Crimea suka ci birnin Moscow
, yana kona komai sai dai Kremlin. Tarihi ya nuna cewa mutane 30,000 ne kawai cikin mazauna 200,000 suka tsira.