Kammala wannan jumla: Ofishin farko na MSF ya kasance a babban birnin Nicaragua, Managua, inda wani
Girgizar kasa ta 1972 ta lalata yawancin garin kuma ta kashe mutane tsakanin 10,000 da 30,000. Kungiyar, a yau an san ta da saurin amsawa a cikin gaggawa, ta isa kwana uku bayan Red Cross ya kafa aikin agaji. A ranar 18 da 19 ga Satumba, 1974, Guguwar Fifi ta haifar da ambaliyar ruwa a Honduras kuma ta kashe dubban mutane (ƙididdigar sun bambanta), kuma MSF ta kafa aikinta na farko na dogon lokaci.