Kammala jumla mai zuwa: Halin da ake yi na zamani na 2nd Marine Regiment ya samo asali ne daga kunna shi a matsayin 1st Advance Base Regiment a Philadelphia Naval Shipyard a ranar 19 ga Yuni, 1913. A shekara mai zuwa wannan sunan ya canza zuwa 1st Regiment, Advanced Base Force. Wannan rukunin ya sauka a matsayin wani ɓangare na haɗin gwiwa don tabbatar da kuma mamaye tashar jiragen ruwa na Veracruz na Mexico a shekara ta 1914. Wannan gamuwa ta ɗan gajeren lokaci ya haifar da lambar yabo ta girmamawa (MOH) guda biyu ga membobin rundunar, Wendell C. Neville da Smedley D. Butler. A shekara mai zuwa, an ba da umurni ga rundunar.
An tura shi zuwa Cap Hatien, Haiti, don kare rayukan Amurkawa da dukiyoyinsu. Wannan ya juya zuwa aiki mai tsawo lokacin da rundunar ta yi amfani da shi sosai, ta shiga cikin manyan hare-haren wuta, kuma ta horar da 'yan sanda na gida. Mafi shahararren aiki guda ɗaya shine ragewar Fort Riviere, sanannen sanannen 'yan tawaye. Smedley Butler da Daniel Daly duk an ba su lambar yabo ta biyu don ayyukan da suka yi a Haiti. A cikin 1916, an sake sanya rukunin a matsayin 2nd Regiment, 1st Brigade. A shekara ta 1933, an sake sanya sunan 2nd Regiment zuwa "2nd Marines". A shekara mai zuwa, 2nd Marines ya bar Haiti sannan aka rushe shi a ranar 15 ga Agusta, 1934.