Acetylsalicylic acid ne da sauri tunawa ta hanyar cell membrane a cikin acidic yanayi na ciki. A lokacin da kara pH da kuma mafi girma surface yankin na kananan hanji sa aspirin da za a tunawa more sannu a hankali akwai, kamar yadda mafi yawan shi ne ionized. Saboda da samuwar concretions, aspirin ne tunawa da yawa sannu a hankali a lokacin overdose, da kuma plasma matakan iya ci gaba da tashi har zuwa 24 hours bayan ingestion. Game da 50<unk>80% na salicylate a cikin jini da aka daura wa albumin furotin, yayin da sauran ya rage a cikin aiki, ionized jihar. Protein ne dogara da ionization. Saturation na sites take kaiwa zuwa free glucuronic acid da kuma ƙara girma na salicylic acid ne da yawa fiye da 0.5% (105%).
0.1 zuwa 0.2 L/kg