Ka cika wannan jumla: Wilson ya nemi dangantaka ta kusa da Latin Amirka, kuma yana fatan ya kafa ƙungiyar 'yan Amirka don yin sulhu a tsakanin ƙasashen duniya. Ya kuma tattauna yarjejeniya tare da Colombia wanda zai biya wannan kasar diyya ga rawar da Amurka ta taka a cikin rabuwa da Panama, amma Majalisar Dattawa ta ci wannan yarjejeniyar. Duk da haka, Wilson sau da yawa ya shiga cikin al'amuran Latin Amurka, yana cewa a 1913: "Zan koya wa jamhuriyoyin Kudancin Amirka su zabi mutanen kirki". Jamhuriyar Dominica ta kasance mai karewa ta Amurka tun lokacin shugabancin Roosevelt, amma ta sha wahala daga rashin kwanciyar hankali. A shekara ta 1916, Wilson ya aika da sojoji zuwa tsibirin, kuma sojojin Amurka za su kasance har zuwa 1924. A shekara ta 1915, Amurka
ya shiga cikin Haiti bayan wani tawaye ya kifar da gwamnatin Haiti, ya fara aiki wanda zai ci gaba har zuwa 1919. Wilson kuma ya ba da izinin shiga tsakani na soja a Cuba, Panama, da Honduras. Yarjejeniyar Bryan-Chamorro ta 1914 ta mai da Nicaragua ta zama wata kariya ta gaskiya, kuma Amurka ta sanya sojoji a can a duk lokacin shugabancin Wilson.