Ka cika wannan furcin: A shekara 16, Armstrong ya soma yin gasa a matsayin mai tsere na tsere uku kuma ya zama zakaran tsere na tsere uku a shekara ta 1989 da kuma 1990. A cikin 1992, ya fara aikinsa a matsayin ƙwararren ɗan tseren keke tare da ƙungiyar Motorola. Ya yi nasara tsakanin 1993 da 1996 tare da Gasar Duniya a
1993, Clásica de San Sebastián a shekarar 1995, Tour DuPont a shekarar 1995 da 1996, da kuma nasarar nasara a Turai, ciki har da mataki na 8 na 1993 Tour de France da mataki na 18 na 1995 Tour de France. A shekara ta 1996, an gano cewa yana da cutar kansa mai saurin yaduwa. Bayan ya warke, ya kafa Gidauniyar Lance Armstrong (yanzu Gidauniyar Livestrong) don taimakawa sauran masu tsira daga cutar kansa.