<unk> <unk> <unk> <unk> <unk>  Passage: Vascular and neural diseases are closely related and intertwined. ️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️ The first pathological change in the small blood vessels is narrowing of the blood vessels.<unk> The first pathological change in the small blood vessels is narrowing of the blood vessels. As the disease progresses, neuronal dysfunction correlates closely with the development of blood vessel abnormalities, such as capillary basement membrane thickening and endothelial hyperplasia, which contribute to diminished oxygen tension and hypoxia.<unk> As the disease progresses, neuronal dysfunction correlates closely with the development of blood vessel abnormalities, such as capillary basement membrane thickening and endothelial hyperplasia, which contribute to diminished oxygen tension and hypoxia. Neuronal ischemia is a well-established characteristic of diabetic neuropathy. Agents blood vessel opening agents (e. g., ACE inhibitors, α1- antagonists) can lead to substantial improvements in neuronal blood flow, with corresponding improvements in nerve conduction velocities. <unk> Agents blood vessel opening agents (e. g., ACE inhibitors, α1- antagonists) can lead to substantial improvements in neuronal blood flow, with corresponding improvements in nerve conduction velocities. <unk> Agents blood vessel opening agents (e. g., ACE inhibitors, α1- antagonists) can lead to substantial improvements in neuronal blood flow, with corresponding improvements in nerve conduction velocities. ️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️<unk>️  Question: What do agents that dilate blood vessels do to the flow of neuronal blood?<unk>Question: What do agents that dilate blood vessels do to the flow of neuronal blood?
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