January 2016, Renzi wuxuu sii waday siyaasadiisa ku wajahan Afrika; Ra'iisul Wasaaraha wuxuu safar saddex maalmood ah ku tagay Nigeria, Ghana iyo Senegal. Shaqooyinka ugu muhiimsan ee safarkan diblomaasiyadeed waxay ahaayeen la dagaalanka argagixisada Islaamka iyo dhibaatada muhaajiriinta
Badda Mediterranean-ka; Madaxweynaha Nigeria Muhammadu Buhari, Renzi wuxuu la saxiixday heshiis lagu xoojinayo iskaashiga u dhexeeya Booliska Nigeria iyo Talyaaniga.