Buuxi weedha soo socota:
Cudurka Soho ee ka dillaacay London sanadkii 1854 ayaa la joojiyay kadib markii dhakhtarka John Snow uu ogaaday in bamka xaafadda ee Broad Street uu ku sumoobay wuxuuna ku qanciyay saraakiisha inay ka saaraan qabashadiisa. Snow wuxuu aaminsanaa in biyaha ay ku jiraan jeermiska ay yihiin isha kolera, halkii ay ka ahaan lahaayeen walxaha hawada ku jira (oo loo yaqaan "miasmata"). Daraasadiisu waxay cadeysay in biyaha wasakhaysan ay yihiin waxyaabaha ugu badan ee keena cudurka shuban biyoodka, inkastoo uusan aqoonsanayn wasakheynta. Inkastoo Filippo Pacini uu go'aamiyay "Vibrio cholerae" inuu yahay kan keena cudurka daacuunka sanadkaas, sanado badan ayaa ka soo wareegi doona ka hor intaan aragtida miasma la helin.