Buuxi weedhan soo socota: Intii uu Charles V hoggaaminayay shirweynihii Worms, Francis I ee Faransiiska wuxuu u diray jeneraalkiisii Robert de la Marck inuu ku soo duulo Burgundian Low Countries wuxuuna taageeray Henry II ee Navarre olole uu ku soo ceshanayo Navarre Iberian. Boqorku wuxuu ku jawaabay isagoo ku dhawaaqay in Francis laga xayuubiyay Milan oo uu sameeyay isbahaysi ka dhan ah Faransiiska oo uu la yeeshay Pope Leo X (8 May 1521), oo xiiseynayay inuu ku biiro dhulalka istiraatiijiyadeed ee Parma iyo Piacenza, oo labaduba qayb ka ah Milan oo Faransiiska gacanta ku haysay. Dagaalkii Afarta Sano ayuu ku bilaawday. Dhanka kale, Cortés ayaa hareereeyay (26ka Maajo) oo qabsaday (13 Ogosto)
Tenochtictlan, oo dhameystirey qabsashadii Aztec Empire. Markabkii siday hantidii ugu weyneyd ee amiir Cuauhtémoc waxaa qabsaday Jean Fleury, laakiin 120,00 ducats oo dahab ah ayaa gaadhay khasnadda Imperial intii lagu jiray khilaafka Talyaaniga. Renaissance Italy waxaa ku tilmaamay Mercurino di Gattinara inuu ahaa "aasaaska ugu weyn ee boqortooyada" iyo Francis I iyo Charles V, oo loo tixgeliyey boqorrada Yurub ee ugu awoodda badan waqtigaas, waxay ku hamiyeen inay ka sarreeyaan badhtamaha hodanka ah. Sida taariikhyahankii Renaissance Francesco Guicciardini uu sharaxay: