IgA1 waa mid ka mid ah laba subclasses immunoglobulin (midka kale waa IgD) in uu yahay O-glycosylated on tiro ka mid ah haraaga serine iyo threonine ee gobolka xijaab proline-hodan gaar ah. glycosylation Aberrant ee IgA u muuqataa in ay keeni polymerisation ee molecules IgA ee unugyada, gaar ahaan mesomerular mesangium. hab la mid ah ayaa la sheegtay in ay hoos Henoch<unk>Schönpura purlein, a vasculitis in inta badan saameeyaa carruurta iyo ka muuqan kara ku lugta kelyaha in uu yahay ku dhowaad indescribable ka gala galaphitis IgA. Si kastaba ha ahaatee, cilmi aadanaha ayaa lagu ogaaday in degalactosylation of IgA1 dhacdaa la nephropathy IgA oo keliya ku dhaca gudaha caloosha (midka kale waa IgD) in ay dhacdo oo kaliya ka dib markii uu ku soo ururiyey antibodies ka soo horjeeda qaab-dhismeedka IgA1 waxaa laga yaabaa in ay sabab u tahay anti-gly
caruurta