Pato wuxuu xirfadiisa ciyaareed ku bilaabay kooxda Internacional sanadkii 2000, wuxuuna ciyaarihiisa ugu horeysay ka ciyaaray sanadkii 2006 isagoo 16 jir ah. Wuxuu dhaliyay 12 gool 27 kulan oo uu u saftay kooxdiisa wuxuuna ka caawiyay inay ku guuleystaan Koobka Adduunka ee Kooxaha FIFA 2006. Bishii Agoosto 2007, wuxuu u saxiixay kooxda Talyaaniga ee AC Milan. Sanadkii 2009, wuxuu dhaliyay 18 gool 42 kulan oo tartamada oo dhan ah, taas oo ku kasbatay abaalmarinta Golden Boy iyo Serie A Young Footballer of the Year. Intii lagu jiray xilli ciyaareedkii 2010-11, wuxuu ka caawiyay Milan inay ku guuleystaan Serie A
, halkaas oo uu ahaa gool dhaliyaha ugu sareeya kooxda isagoo dhaliyay 14 gool 25 kulan. Bishii Janaayo 2013, Pato wuxuu ku soo laabtay Brazil isagoo u saxiixay Corinthians lacag dhan € 15 milyan, halkaas oo uu kula guuleystay Campeonato Paulista kooxda. Sanadkii 2014, Pato wuxuu ku biiray São Paulo heshiis amaah ah oo laba sano ah, halkaas oo uu ku ciyaaray 95 kulan, isagoo dhaliyay 38 gool kooxda. Bishii Janaayo 2016, Pato wuxuu u wareegay kooxda Premier League ee Chelsea heshiis amaah ah, ka hor inta uusan u dhaqaaqin kooxda reer Spain ee Villarreal isla sanadkaas. Sanadkii 2017, wuxuu u saxiixay kooxda Shiinaha ee Tianjin Tianhai, sanadka 2019, wuxuu ku soo laabtay São Paulo.