U fiirso qoraalka hoose ka dibna ka jawaab su'aasha kadib isla luqadda qoraalka:  Aragtiyo ku saabsan sida dhiigu u xidhmo ayaa jirtay tan iyo waqtiyadii hore. Johannes Müller (1801<unk>1858) oo ahaa cilmi baare ku takhasusay cilmiga jidhka ayaa sharaxay fibrinka, oo ah walxaha ku jira dhiigga. Horudhackeeda lagu milmi karo, fibrinogen, waxaa sidaas u magacaabay Rudolf Virchow (1821<unk>1902), waxaana si kiimiko ah u go'doomiyay Prosper Sylvain Denis (1799<unk>1863). Alexander Schmidt wuxuu soo jeediyay in beddelidda fibrinogen ilaa fibrin ay tahay natiijada geedi socodka enzymatic, wuxuuna ku calaamadeeyay enzyme-ka mala-awaalka ah "thrombin" iyo horudhackiisa "prothrombin". Arthus wuxuu ogaaday 1890 in kalsiyumku uu muhiim u yahay xinjirowga Platelets waxaa la aqoonsaday 1865, shaqadooda waxaa cadeeyay Giulio Bizzozero 1882. Marxaladdan, waxaa la ogaa in thrombokinase/thromboplastin (factor III) ay sii daayaan unugyada dhaawacan, oo la falgalaya prothrombin (II), kaas oo, kalsiyum (IV), ay sameeyaan thrombin, kaas oo u beddelaya fibrinogen fibrin (I).  Su'aal: Goorma ayuu noolaa Muller?
1801<unk>1858