Buuxi weedha soo socota: Manuel wuxuu dhashay c. 1516 ee Évora waxay u tagtay Joana de Vilhena iyo Dom Francisco of Portugal (1485<unk>1549), 1aad Count of Vimioso. Wuxuu helay cinwaanka Comendador ee Vimioso iyo São Pedro de Calvelo, waxaana si weyn u tixgeliyey John Manuel, Amiirkii Boortaqiiska, aabaha boqorka mustaqbalka Sebastian ee Boortaqiiska. Xilligii uu boqorka ahaa, Sebastian wuxuu u magacaabay Danjiraha Boortaqiiska ee Castile. Ka dib geeridii naxdinta lahayd ee Boqor Sebastian ee
Dagaalkii Alcácer Quibir, Dom Manuel wuxuu taageeray Dom António, Prior of Crato ee xiisadda dhaxalka ee raacday.