Conan Doyle wuxuu si joogta ah u sheegay in Holmes uu ku dhiiraday sawirka nolosha dhabta ah ee Joseph Bell, oo ah dhakhtar qalliin ah oo ku yaal Royal Infirmary of Edinburgh, oo uu Conan Doyle la kulmay 1877 oo uu u shaqeeyay sidii xafiisle. Sida Holmes, Bell waxaa lagu yaqaanay inuu soo saaro natiijooyin ballaaran oo laga soo qaatay aragtiyo daqiiqado ah. Si kastaba ha noqotee, wuxuu markii dambe u qoray Conan Doyle: "Adiga qudha ayaa ah Sherlock Holmes oo aad u fiican waad ogtahay". Sir Henry Littlejohn, oo ah Guddoomiyaha Cilmiga Caafimaadka ee Jaamacadda Edinburgh Medical School, ayaa sidoo kale loo soo xigtay inuu yahay waxyihi Holmes. Littlejohn, oo sidoo kale ahaa Dhakhtarka Booliska iyo Sarkaalka Caafimaadka ee Caafimaadka ee Edinburgh, wuxuu siiyay Conan Doyle xiriir u dhexeeya baaritaanka caafimaadka iyo ogaanshaha dembiga.
ka soo saarista natiijooyin ballaaran oo laga soo qaatay aragtiyo kooban