PWS waxaa sabab u ah dhacdo epigenetic ah oo loo yaqaan 'imprinting', oo ay sabab u tahay tirtirka nuqulada aabbe ee SNRPN iyo NDN necdin genes oo ay weheliso kooxo snoRNAs ah: SNORD64, SNORD107, SNORD108 iyo laba nuqul oo ah SNORD109, 29 nuqul oo ah SNORD116 (HBII-85) iyo 48 nuqul oo ah SNORD115 (HBII-52). Kuwani waxay ku jiraan chromosome 15 oo ku yaal gobolka 15q11-13.
dhacdada loo yaqaano " Imprinting "