Paracetamol wuxuu ka kooban yahay halbeeg benzene ah, oo lagu beddelay hal koox hydroxyl ah iyo atomka nitrogen ee koox amide ah oo ku jira qaabka para (1,4). Kooxda amide waa acetamide (ethanamide). Waa nidaam si ballaaran loo isugu daray, sida hal lammaane oo keli ah oo ku yaal oksijiinta hydroxyl, daruurta benzene pi, lammaanaha nitrogen kali ah, orbitalka p ee ku yaal kaarboon kaarboon, iyo hal lammaane oo keli ah oo ku yaal oksijiinta karboonka ayaa dhammaantood isku daray. Jiritaanka laba kooxood oo firfircoon ayaa sidoo kale ka dhigaya giraanta benzene inay si aad ah uga falceliso beddelaadda aromatic electrophilic. Maaddaama beddelaaduhu yihiin ortho, para-directing iyo para marka loo eego midba midka kale, dhammaan jagooyinka ku yaal giraanta ayaa si siman ama ka yar u siman.
wuxuu yareeyaa aasaaska oksijiinta iyo nitrogen-ka