Fisiologist Johannes Müller (1801<unk>1858) ayaa sharaxay fibrin, maaddada thrombus. Horudhackeeda dabiiciga ah, fibrinogen, waxaa sidaas u magacaabay Rudolf Virchow (1821<unk>1902), waxaana si kiimiko ah u go'doomiyay Prosper Sylvain Denis (1799<unk>1863). Alexander Schmidt wuxuu soo jeediyay in isbedelka fibrinogen ilaa fibrin uu yahay natiijada geedi socodka enzymatic, wuxuuna ku calaamadeeyay enzyme-ka mala-awaalka ah "thrombin" iyo horudhackiisa "prothrombin". Arthus wuxuu ogaaday 1890 in kalsiyumku muhiim u yahay isku-dheelitirka. Platelets waxaa la aqoonsaday 1865, shaqadooda waxaa lagu ogaadey Giulio Bizzoid 1882.
1801<unk>1858