Magaca Ioannina wuxuu soo muuqday markii ugu horeysay 879, qoraalkii Golaha Afaraad ee Constantinople, oo tixraacaya mid ka mid ah Zacharias, Bishop of Ioannine, a suffragan of Naupaktos. Ka dib markii
Guushii Byzantine ee Bulgaria, 1020 Emperor Basil II () wuxuu hoos geliyay hoggaanka kiniisadda maxalliga ah ee Archbishopric of Ohrid. Heshiiskii qeybinta dhulka Byzantine kadib Dagaalkii Saddexaad ee Laanqayrta, Ioannina waxaa loo ballanqaaday dadka Venetians, laakiin dhacdada, waxay noqotay qayb ka mid ah boqortooyadii cusub ee Epirus, oo uu aasaasay Michael I Komnenos Doukas.