Buuxi weedha soo socota: Magaca Ioannina wuxuu soo muuqday markii ugu horreysay 879, go'aannada Golaha Afaraad ee Constantinople, oo tixraacaya mid ka mid ah Zacharias, Bishop of Ioannine, oo ah sufragan of Naupaktos. Ka dib markii
Guushii Byzantine ee Bulgaria, 1020 Emperor Basil II wuxuu hoos geeyay hoggaanka kiniisadda maxalliga ah ee Archbishopric of Ohrid. Khabiirka qadiimiga ah ee Giriigga K. Tsoures ayaa taariikhda derbiyada magaalada Byzantine iyo qalcadda waqooyi-bari ee Qasriga Ioannina ilaa qarnigii 10aad, iyada oo lagu daray qarnigii 11aad, oo ay ku jirto qalcaddii koonfur-bari, oo dhaqan ahaan loo aaneynayo qabsashada muddada gaaban ee magaalada ee Norman ee hoos imaanaysay hoggaanka Bohemond ee Taranto 1082. In a chrysobull in Venetians ee 1198, magaalada waxaa ku qoran sida qayb ka mid ah gobolka u gaar ah ("provincia Joanninorum" ama "Joaninon"). Heshiiskii qeybinta dhulka Byzantine ka dib Dagaalkii Saddexaad ee Saliibiyiinta, Ioannina waxaa loo ballanqaaday dadka Venetians, laakiin dhacdada, waxay noqotay qayb ka mid ah gobolka cusub ee Epirus, oo uu aasaasay Michael I Komnenos Doukas.