Morse wuxuu guursaday Lucretia Pickering Walker bishii Sebtember 29, 1818, ee Concord, New Hampshire. Waxay dhimatay Febraayo 7, 1825, wax yar ka dib dhalashadii ilmahooda saddexaad (Susan b. 1819, Charles b. 1823, James b. 1825). Wuxuu guursaday xaaskiisa labaad, Sarah Elizabeth Griswold bishii Agoosto 10, 1848, ee Utica, New York wuxuuna lahaa afar carruur ah (Samuel b. 1849, Cornelia b. 1851, William b. 1853, Edward b. 1857). Su'aal: Magaaladee Sarah Elizabeth Griswold ku guursaday?
Utica