Niggli wuxuu ku dhashay Zofingen wuxuuna wax ku bartay Swiss Federal Institute of Technology (ETH) oo ku taal Zurich iyo Jaamacadda Zurich, halkaas oo uu ku qaatay shahaado dhakhtar. Buugiisa 1919, Geometrische Kristallographie des Diskontinuums, wuxuu door muhiim ah ka ciyaaray hagaajinta aragtida kooxda booska. Buuggan, Niggli wuxuu ku muujiyey in inkasta oo xaaladaha dib-u-eegista X-ray aysan had iyo jeer si gaar ah u go'aamin kooxda booska ee ay ka tirsan tahay kristal, haddana waxay muujinayaan tiro yar oo ah kooxaha booska ee suurtagalka ah ee ay ka mid noqon karto.
Machadka Farsamada ee Swiss (ETH) ee Zurich iyo Jaamacadda Zurich