January 2003, Sharpton wuxuu si rasmi ah ugu dhawaaqay musharaxnimadiisa wuxuuna si ballaaran uga ololeeyay gobolka South Carolina. Si kastaba ha noqotee, ka dib markii uu si liidata uga soo muuqday doorashadii hore ee Koonfurta Carolina, Sharpton wuxuu ku dhawaaqay inuu taageerayo musharaxa ugu dambeeya ee Dimuqraadiga John Kerry. Si kastaba ha ahaatee, Sharpton wuxuu sii waday ololihiisa ilaa Shirweynihii Qaranka ee Dimuqraadiga
, halkaas oo uu ka jeediyay khudbad muhiim ah.