Nucleases waxaa loo yaqaanaa exonucleases, halka endonucleases ay ka go'an yihiin gudaha xargaha. Nucleases-ka ugu badan ee loo isticmaalo bayoolajiyada molecular-ka waa xaddidaadda endonucleases, kuwaas oo go'a DNA-da taxane gaar ah. Tusaale ahaan, enzyme-ka EcoRV ee bidix ka muuqda wuxuu aqoonsan yahay taxanaha 6-base 5′-GATC-3′ wuxuuna goynayaa khadka toosan. Dabeecadda, enzymes-kaani waxay ka ilaaliyaan bakteeriyada infekshanka phage iyagoo dheefshiidaya DNA-da phage marka ay galaan unugyada bakteeriyada, oo qayb ka ah nidaamka xaddidaadda. Teknolojiyada taxanaha, nucleases-kan qaaska ah waxaa loo isticmaalaa DNA-da molecular iyo farta farta. Su'aal: Waa maxay enzyme EcoRV?
Liiska 6-saldhig 5′-GATATC-3