Nyorera kupfuurira kweiyi ndima - O'Rourke akatsigira chibvumirano cheIran chenyukireya pamusoro pekugadzirwa kweIran kwezvombo zvekuparadza kwakawanda. Muna Nyamavhuvhu 2017, O'Rourke akatsoropodza mafungiro akaoma aTrump kuNorth Korea, achiti "Hatifanire kubvumidza mutungamiri wenyika uyu kuti aite kuti nyika ino irarame, kana kuti tweet nyika ino, muhondo neNorth Korea". Muna Kurume 2019, O'Rourke akadaidzira kupera kweHondo yeIraq inotungamirwa neUS uye Hondo muAfghanistan. O'Rourke akapikisa kubatanidzwa kweU.S. muSyria Civil War uye kupa zvombo kune varwi vanopandukira muSyria. Akatsoropodzawo kupindira kwemauto kweNATO muLibya
"chinhu chinoparira kusagadzikana kweMiddle East uye kusimuka kweISIS". O'Rourke akatsigira mutemo wokuderedza NSA kuongorora kwakapararira uye kusina kukodzera kwevagari vemuU.S. nevokune dzimwe nyika.