Nyora kupfuurira kweiyi ndima - Muna 678, Nu'man akagadzwa gavhuna weKufa naMu'awiya. Muna 680, Mu'awiya akafa uye akatsiviwa nemwanakomana wake Yazid I, uyo akazotsiva Nu'man naUbayd Allah ibn Ziyad muna 680, chikamu semhedzisiro yekupindura kwakashata kwaNu'man kune zviitiko zvinopesana neUmayyad zveMuslim ibn Aqil, uyo aiunganidza rutsigiro muguta raHusayn ibn Ali. Muna 682, Yazid akatumira Nu'man kuMedina kuti aite kuti vaAnsar vawirirane nehurumende yake, asi akatadza kuwana rutsigiro rwavo. Mushure mekufa kwaYazid, Nu'man akaziva Mecca-based, anti-Umayyad caliph Abd Allah ibn al-Zubayr, uyo akagadza Nu'man kunzvimbo yake yekare yedunhu muHoms. Izvi zvakamubatanidza nemadzinza eQaysi aidzora kuchamhembe kweSyria uye magavhuna eDhamasiko nePalestine, al-Dahhak ibn Qays al-Fihri naNatel ibn Qays al-Judhami. Mapato maviri akasangana paHondo yeMarj Rahit
muna 684, panguva iyo Nu'man akatumira Shurahbil ibn Dhi'l-Kala uye vekupedzisira veHimyari vemadzinza kubva kuHoms garrison kujoina al-Dahhak. Mushure mekugamuchira mishumo yekuti madzinza eQaysi anotungamirwa na al-Dahhak akange akundwa nevanotsigira Umayyad Banu Kalb, Nu'man akatiza Homs nemukadzi wake, Na'ila bint Umara, uyo akange akaroora Mu'awiya, nevana vake, asi vakateverwa nekuurayiwa nenhengo dzevarindi veHoms. Mudzimai wake nevana vakaponeswa ndokuva pasi pokudzivirirwa naBanu Kalb, dzinza romudzimai wake.