Nyora kuenderera kweiyi ndima - Anonyanya kuzivikanwa nezita rake remadunhurirwa rekuti "Picchio", panguva yebasa rake rekirabhu, De Sisti akatambira kirabhu yekumusha kwake A.S. Roma pazviitiko zviviri (1960<unk>65, 1974<unk>79), uye ACF Fiorentina (1965<unk>74), kuhwina mazita akati wandei epamba uye epasi rese nemakirabhu ese ari maviri. Akaita kutanga kwake muSerie A neRoma mukukunda 2-1 kure neUdinese, musi wa12 Kukadzi 1961, kwaakaona mutambi wenhabvu uye chipangamazano Juan Alberto Schiaffino panguva yake yekutanga kukirabhu. Akafarikanya nguva yake yakabudirira zvikuru neFiorentina, iyo yaisanganisira zita religi muna 1969
, kirabhu yechipiri yakazara, asati adzokera kuRoma muna 1974. Akakunda Coppa Italia nemakirabhu ese ari maviri, muna 1964 na1966.