Pedzisa mutsara unotevera: Muna 1499, Louis XII weFrance akatanga Hondo yechipiri yeItaly, achipinda muLombardy ndokutora Duchy of Milan. Akabva aita chibvumirano naFerdinand I weSpain chokuti Naples igovaniswe. Pakazosvika 1502, mauto akabatana eFrance neSpain akanga atora Umambo; kusawirirana pamusoro pemitemo yokuparadzaniswa kwakatungamirira kuhondo pakati paLouis naFerdinand. Pakazosvika 1503, Louis, arohwa pa
Hondo yeCerignola neHondo yeGarigliano, yakamanikidzwa kuti ibve muNaples, iyo yakasiiwa ichidzorwa nemutongi wechiSpanish, Gonzalo Fernández de Córdoba. Munguvayi, Papa Alexander VI akaedza kubvisa nyika yeBorgia muRomagna kupfurikidza nenhamburiko dzaCesare Borgia.