Passage: Inenge mamaira matatu (4.8 km) kuchamhembe kwemuganhu weCalifornia, mugwagwa mukuru unoyambuka 4,310 tsoka (1,310 m) Siskiyou Summit, nzvimbo yakakwirira pane I-5, uye wobva wadonhera muRogue Valley kuburikidza nemakomo ekumaodzanyemba kweOregon nemataundi akadai seAshland, Medford neGrant Pass. Kutendeuka kuchamhembe kuyambuka mapasi matatu kuenda kuUmpqua Valley uye kuburikidza neRoseburg, makomo anowanzo kutendeuka kuita zvikomo, uye painosvika kuCottage Grove, mugwagwa unopinda muRwizi rweWillamette. PaEugene mugwagwa mukuru unoyambuka I-105, nzira pfupi inoenda kuDowntown Eugene. Dzimwe nzira dzakakwirira dzeguta dzinopindirana neI-5 muEugene Metro. Interstate inobva yaenda kuchamhembe, ichipfuura neAlbany neCorvallis, ichipfuura neSalem, uye ichipfuura neWoodburn.
I-105