Chekupedzisira, rondedzero yekutanga yakaburitswa yechiitiko cheleukemia mumabhuku ekurapa yakatanga muna 1827, apo chiremba wechiFrench Alfred-Armand-Louis-Marie Velpeau akarondedzera murapi wemaruva ane makore makumi matanhatu nematatu akawana chirwere chinoratidzwa nefivha, kushaya simba, matombo emudumbu, uye kuwedzera kwakakura kwechiropa nemasero. Velpeau akacherekedza ropa remunhu uyu raive nehunhu "senge gruel", uye akafungidzira kuoneka kweropa kwaikonzerwa nemapundu corpuscles. Muna 1845, nhevedzano yevanhu vakafa neakakura spleens uye shanduko mu "mavara uye kuenderana kwemasero eropa ravo" yakataurwa neEdinburgh-based pathologist J.H. Bennett; akashandisa izwi rekuti "cococythemia" kurondedzera iyi yakaipa pathological. Izwi rekuti "leukemia" rakagadzirwa naChristian Mosslow, Rudolf Virchow, uyo akawana chirwere chechirwere ichi chakaitika neacidity, kushaya simba, mabwe, uye
kuwedzerwa kwemasero machena eropa muvanhu vane clinical syndrome