The chemakemikari hwaro Markovnikov kuti Rule ndiko kuumbwa zvikuru kugadzikana carbocation panguva wedzerai muitiro. Kuwedzera rehydrogen Ion mumwe kabhoni maatomu ari alkene anosika munhu akanaka mutoro pamusoro mumwe kabhoni, kuumba carbocation intermediate. The zvikuru kutsiviwa ari carbocation, zvikuru kugadzikana zviri, nokuda induction uye hyperconjugation. The chikuru chigadzirwa ari kuwedzera maitiro achava mumwe yakaumbwa kubva zvikuru kugadzikana intermediate. Naizvozvo, chikuru chigadzirwa ari kuwedzera HX (apo X ari mamwe maatomu electronegative pane H) kuti alkene ane rehydrogen maatomu ari zvishoma kutsiviwa chinzvimbo uye X ari zvikuru kutsiviwa chinzvimbo. Asi mumwe zvishoma kutsiviwa, zvishoma kugadzikana carbocation acharamba kuumbwa pane imwe wevasungwa, uye achaita kuti kuva muduku conjugate pamwe rakabatana conjugate, mubvunzo: Kana X zvinoitika zvikuru substiation?
yakatsiga zvikuru