Nyorai kuenderera mberi kweiyi ndima - Van der Breggen akazova nyanzvi muna 2012 ne Muna April, akawana nzvimbo yechipfumbamwe paTour of Flanders, uye muna July, akakunda Tour de Bretagne Féminin. Akakunda zvikamu zvitatu zvezvikamu zvina uye akachengetedza huwandu hwehuwandu hwemaminitsi anenge matatu pamusoro peSophie De Vuyst. Akakundawo mujaho wenguva paTour Féminin en Limousin pamwe negoridhe mumutambo wevakadzi vari pasi pemakore makumi maviri nematatu pamakwikwi eEuropean
. Somugumisiro, akasarudzwa ku2012 World Championships. Achiri kutamba basa remumba kumutungamiriri wechikwata chake, Marianne Vos, akakwanisa kupedza wechishanu mumakwikwi emigwagwa.