Hepatitis B ndeimwe yema pararetroviruses mashoma anozivikanwa: asiri-retroviruses ayo achiri kushandisa reverse transcription mune yavo yekudzokorora maitiro. Utachiona hunopinda muchitokisi nekusunga kuNTCP pamusoro uye kuve endocytosed. Nekuti hutachiona hunowanda kuburikidza neRNA inogadzirwa neanogamuchira enzyme, hutachiona genomic DNA inofanirwa kuendeswa kune host cell nucleus nemapuroteni anonzi chaperones. Iyo partially-double-stranded viral DNA inozoitwa yakazara-yakapetwa nehutachiona polymerase uye inoshandurwa kuita covalently yakavharwa denderedzwa DNA (cccDNA). Iyi cccDNA inoshanda se template yekunyora mana ehutachiona mRNA neanogamuchira RNA polymerase. Iyo mRNA hombe (iyo yakareba kupfuura hutachiona genome), inoshandiswa kugadzira makopi eiyo genome uye kugadzira mapuroteni matsva kubva kune hutachiona hutachiona hutachiona hutachiona hunoshandiswa kudzoreredza hutachiona hutachiona hutachiona uyezve kugadzira mRNA mapuroteni matsva kubva
utachiona hwehepatitis B