Kunyange zvazvo mhando mbiri huru dziri β2 agonists uye anticholinergics; zvose zviripo kwenguva refu-kuita uye pfupi-kuita mafomu. Ivo kuderedza kunonoka kufema, wheeze, uye kurovedza muviri kurambidzwa, zvichiguma nani upenyu. Hazvina kujeka kana ivo kuchinja mberi kwechirwere chepasi. Mune avo vane chirwere chisinganzwisisiki, mishonga pfupi-kuita inokurudzirwa pazvinenge zvichidiwa. Mune avo vane chirwere chakakomba, kwenguva refu-kuita inokurudzirwa. Long-kuita vamiririri vanoshanda muchidimbu nekuderedza hyperinflation. Kana kwenguva refu-kuita bronchodilators vasina kukwana, ipapo corticosteroids inowanzowedzerwa. Ndeupi wevanoshanda kwenguva refu, tiotropium (a-kuita anticholinergics); zvose zviri zviviri zviripo mune mafomu akareba-kuita uye kwenguva refu-kuita.
β2 agonists uye anticholinergics