Tumor dzakaipa dzomupapu dzaingova 1% chete yemakenza ose akaonekwa pakuvhiya muna 1878, asi dzakanga dzasimuka kusvika ku10~15% pakutanga kwema1900. Mishumo yezviitiko munyika yose muzvinyorwa zvekurapa yakanyorwa chete 374 muna 1912, asi kuongororwa kwekuvhiya kwakaratidza kuti kuwanda kwekenza yemapapu kwakanga kwakawedzera kubva pa0.3% muna 1852 kusvika pa5.66% muna 1952. MuGermany muna 1929, chiremba Fritz Lintick akaziva kubatana pakati pekuputa uye kenza yemapapu, izvo zvakatungamira mukushambadzira kwekuputa. Chidzidzo cheBritish Doctors, chakaburitswa muma1950, chaive chiratidzo chekutanga chakasimba chechirwere chechirwere pakati pekuputa nekenza yemapapu.
kusvuta fodya