Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Holmes nguva nenguva anoshandisa zvinodhaka zvinopesvedzera, zvikurukuru mukushayikwa kwemhaka dzinonyandura. Anoshandisa cocaine, yaanozvibaya jekiseni mumushonga une zvikamu zvinomwe kubva muzana nesirinji inochengetwa muhomwe yeganda reMorocco. Kunyange zvazvo Holmes achiedzawo morphine, anoratidza kusatendera kwake kwakasimba paanoshanyira nzvimbo inochengeterwa opium; zvinodhaka zvose zviri zviviri zvakanga zviri pamutemo muEngland yomuzana remakore rechi19. Somurapi, Watson anoramba zvakasimba tsika yeshamwari yake yekushandisa cocaine, achirondedzera se"chivi choga" chemutikitivha, uye ane hanya nemigumisiro yacho pautano hwepfungwa hwaHolmes nepfungwa. Mu"The Adventure of the Missing Three-Quarter", Watson anoti kunyange zvazvo "asisina" Holmes pamishonga, mutikitivha wacho anoramba ari mupindwa muropa ane tsika yoku"safa, asi kungorara".  Mubvunzo: Ipuresentii yemhinduro dzinoshandiswa?
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