Pakupedzisira, chiremba wechiFrench Alfred-Armand-Louis-Marie Velpeau akarondedzera mumwe murume ane makore makumi matanhatu nematatu ane chirwere chakaratidzirwa nefivha, kushaya simba, mabwe emudumbu, uye kuwedzera kwakanyanya kwechiropa uye tsvina. Velpeau akacherechedza kuti ropa remunhu uyu raive neyakafanana "senge gruel", uye akafungidzira kuti kuoneka kweropa kwaive nekuda kwemahara corpuscles. Muna 1845, nhevedzano yevanhu vakafa neakawedzerwa spleens uye shanduko mu "mavara uye kuenderana kwemasero eropa ravo" yakataurwa neEdinburgh-based pathologist J.H. Bennett; akashandisa izwi rekuti "cocythemia" kurondedzera iyi yakaipa pathological. Izwi rekuti "cocytemia" rakanyorwa naChristian Moschow, chiremba wemaruva Rudolf Virchow, uye rakaonekwa muna 1869.
Makore 1877