Hondo iyi yakachinja mamiriro ezvinhu pakati penyika mbiri idzi muMediterranean uye yakasimbisa Royal Navy munzvimbo yakasimba iyo yakachengetwa kwehondo yese. Yakakurudzirawo dzimwe nyika dzeEurope kuti dzirwise France, uye yaive chinhu chakakonzera kutanga kweHondo yeChipiri Coalition. Mauto aBonaparte akabatwa muEjipitori, uye kutonga kweRoyal Navy pamhenderekedzo yeSyria kwakabatsira zvakanyanya kukundwa kweFrance paKukomberedzwa kweAcre muna 1799 iyo yakatungamira kudzoka kwaBonaparte kuEurope. Nelson akakuvadzwa muhondo iyi, uye akaziviswa segamba muEurope yese uye akazoitwa Baron Nelson, kunyangwe aive asingagutsikane nemubairo wake.
Royal Navy