Mushure mekuratidza kuti ma enzymes aigona kushanda kunze kwesero mhenyu, danho raitevera raive rekutsvaga chimiro chavo. Vazhinji vashandi vekutanga vakacherekedza kuti chiitiko che enzymatic chaibatanidzwa nemapuroteni, asi masayendisiti akati wandei (senge mubairo weNobel Richard Willstätter) akataura kuti mapuroteni aingova vatakuri vechokwadi ma enzymes uye kuti mapuroteni pachawo aisakwanisa kuita catalysis. Zvisinei, muna 1926, James B. Sumner akaratidza kuti enzyme urease yaive puroteni yakachena uye akaibvisa; Sumner akaita zvakafanana ne enzyme catalase muna 1937. Mhedziso yekuti mapuroteni akachena anogona kuve ma enzymes yakaratidzwa zvachose naNorthropites naStanley, avo vakashanda pama enzymes ekugaya pepsin (1930), trypsin uye chymotrypsin. Masayendisiti matatu aya akapihwa mubairo weNobel mu1946.
Mubairo weNobel muChemistry