Muna Zvita 2007, Witherspoon akatanga kushanda naVince Vaughn, vachitora firimu remutambo wezororo Four Christmases, nyaya pamusoro pevaviri vanofanirwa kupedza zuva ravo reKisimusi vachiedza kushanyira vese vabereki vavo vana vakarambana. Firimu rakaburitswa muna Mbudzi 17, 2008. Kunyangwe ichitsoropodzwa nevatsoropodzi, bhaisikopo rakave budiriro yebhokisi, ichiwana mari inodarika $ 120 mamirioni mudzimba uye $ 157 mamirioni pasirese. Muna 2009, Witherspoon akataura Susan Murphy, hunhu hunotungamira muDreamWorks 'computer-animated firimu Monsters vs. Aliens, yakaburitswa munaKurume 2009, ichiva yake hombe hit panguva iyoyo. Akagadzirawo Legally Blonde spin-off Legally Blondes, inotamba naMilly naBecky Rosso. Zvisinei, Witherspoon haana kuoneka mufirimu yeupenyu-chiitiko kwemakore maviri mushure mekuburitswa kweKisimusi ye2008 Four Christmases.
Mbudzi 2008