Louis Pasteur akakundikana kuwana chinokonzera rabies uye akafungidzira pamusoro pechirwere chechirwere chakanga chiri chiduku kuti chionekwe uchishandisa microscope. Muna 1884, French microbiologist Charles Chamberland akagadzira firita (inozivikanwa nhasi seChamberland firita kana Pasteur-Chamberland firita) ine pores duku kupfuura mabhakitiriya. Nokudaro, aigona kupfuudza mhinduro ine mabhakitiriya kuburikidza nefirita uye akavabvisa zvachose. Muna 1892, muRussia biologist Dmitri Ivanovsky akashandisa firita iyi kuti adzidze izvo zvino zvinozivikanwa sehutachiona hwefodya. Kuedza kwake kwakaratidza kuti mashizha emashizha akaomeswa kubva mumiti yefodya yakasvibiswa akaramba achirwara mushure mekuchenesa. Ivanovsky akataura kuti hutachiona hwacho hunogona kunge hwaive nehutachiona hunogadzirwa nehutachiona, asi haana kutevera pfungwa yacho. Panguva iyoyo zvaifungidzirwa kuti hutachiona hunogona kuchengetwa nehutachiona hwehutachiona uye hutachiona hwehutachiona hwehutachiona hwehutachiona hunogona kuwanikwa kuburikidza nehutachiona
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