Vanhu vanonzi vane chirwere chemasero asina kuchena, vanotsiviwa neanonzi hemoglobin S. Muchirwere chemasero asina kuchena, haemoglobin S inotsiva ese ari maviri e-globin subunits muhemoglobin cell. Haemoglobin A2, iyo ine maviri e-alpha uye maviri e-delta maketeni, uye haemoglobin F, iyo ine maviri e-alpha uye maviri e-gamma maketeni mumiviri yavo. Pakati pemhando nhatu idzi, haemoglobin F inotonga kusvika pamasvondo matanhatu ezera. Mushure meizvozvo, haemoglobin A inotonga muhupenyu hwese. Muvanhu vakaonekwa vane chirwere chemasero asina kuchena, kanenge kamwe chete ke β-globin subunits mu haemoglobin A kanotsiviwa neanozivikanwa se haemoglobin S. Muchirwere chemasero asina kuchena, haemoglobin S inotsiva ese ari maviri e-globin subunits mu haemoglobin cell. Haemoglobin A2, iyo ine mamiriro e-autosomal anodzokorora e-alpha uye maviri e-
haemoglobin A