Nyorai kupfuurira kweiyi ndima - Wheldon akaramba ari nePanther Racing nokuda kwemwaka wa 2010. Munguva yekuvhura mwaka weSão Paulo Indy 300, akasangana naAlex Tagliani, uyo akamutumira kuKanaan; akapora kuti apedze wechishanu. Makwikwi matatu gare gare paToyota Grand Prix yeLong Beach, Wheldon akatora mugumisiro wechipiri wepamusoro gumi nechinomwe. MuIndianapolis 500
, Wheldon akatanga kubva panhamba gumi nesere. Akapfuura nomumunda achishandisa nzira yokumira mumakomba kuti ave wechipiri kwegore rechipiri mumutsetse. Wheldon akaramba achikwikwidzana gore rose; achinetsa nokuda kwokukunda pamakwara eOval. Pasinei nokuratidzira kwakasimba, haana kukwanisa kutora kukunda kwemakwikwi munguva yake nePanther Racing, iyo yakavhiringidza John Barnes. MuIndy Grand Prix yeSonoma paInfineon Raceway (zvino Sonoma Raceway), Wheldon akaonana nemotokari yaBertrand Baguette panguva yekudziya-kumusoro pamberi pekutanga kwechiitiko. Akapidiguka uye akafambisa-fambisa kanoverengeka asi akabuda asina kukuvara. Kupedza kwake kwakanaka kwegore kwaiva nzvimbo yechipiri muPeak Antifreeze &amp; Motor Oil Indy 300 paChicagoland Speedway. Akauya wechipfumbamwe mumakwikwi ekupedzisa mwaka weCafés do Brasil Indy 300 kuHomestead Miami Speedway, kuti ave wechipfumbamwe mumakwikwi evatyairi aine 388 mapoinzi.