GH inokurudzirawo, kuburikidza neJAK-STAT signaling pathway, kugadzirwa kwe insulin-like growth factor 1 (IGF-1, yaimbozivikanwa se somatomedin C), hormone yakafanana neproinsulin. Chiropa ndicho chinonyanya kukoshesa GH yeiyi nzira uye ndiyo nzvimbo huru yekugadzirwa kwe IGF-1. IGF-1 ine kukura-kukurudzira migumisiro pane zvakasiyana-siyana zvezvipembenene. IGF-1 inowedzera inogadzirwa mukati mezvipembenene zvinotarirwa, zvichiita kuti zviite se endocrine uye autocrine / paracrine hormone. IGF-1 inewo zvinokurudzira pane osteoblast uye chondrocyte basa rekusimudzira kukura kwemapfupa.Kuwedzera pakuwedzera kukwirira muvana nevechiri kuyaruka, kukura kwehomoni kune zvimwe zvakawanda zvinokonzera muviri: Mubvunzo: Chii chinofananidza?
IGF-1