Pedzisa mutsara unotevera: Muna 2015, Humphrey akatsigira gavhuna weOhio John Kasich kuti ave Mutungamiriri muna 2016. Munguva ye2016 Republican presidential primaries, Humphrey aive mutungamiri wekuedza kuvharira Donald Trump kubva mukuwana kusarudzwa pa
Gungano Renyika reRepublican. Akati, "Ndaizovhotera Hillary [achireva Hillary Clinton, akasarudzwa neDemocratic] chete kana paizova nokukwikwidzana kwakasimba. Zvichakadaro, ndiri kutarisira kuti vatungamiri veRepublican, pakupedzisira, pakupedzisira vacharatidza ushingi uye nheyo dzokushora Trump uye kumuti arege kusarudzwa kana kutarisana nekugadziriswazve kwekokorodzano". Musi waNovember 6, 2016, mazuva maviri sarudzo dzisati dzaitwa, Humphrey akatsigira zviri pamutemo Clinton. Mumwedzi iwoyo, Humphrey akasiya Republican Party ndokuva akazvimirira.