Nyora kuenderera mberi kweiyi ndima - Kubudirira kwaChalamet kwakauya muna 2017 nebasa rake saElio Perlman mumutambo werudo waLuca Guadagnino "Ndidane nezita rako", mushure mezvo akaonekwa mumafirimu ekuuya kwezera "Hot Summer Nights" uye "Lady Bird" pamwe nefirimu rekumadokero "Hostiles". Kuita kwake mu "Ndidane Nezita Rako" kwakamuwanira zita reOscar reMutambi Akanakisisa, zvichiita kuti Timothée ane makore makumi maviri nemaviri ave wechitatu muduku pane vose vakasarudzwa muboka iri uye muduku pane vose
kubva paMickey Rooney ane makore 19 okukura nebasa rake mu"Babes in Arms" muna 1939. Akazotamba Nic Sheff mumutambo "Beautiful Boy" (2018), iyo yaakasarudzwa kuti awane mubairo weGolden Globe, Screen Actors Guild Award, uye BAFTA Film Award, vese veBest Supporting Actor. Muna 2019, Chalamet akaita nyeredzi muWoody Allen's romantic comedy "A Rainy Day in New York". Gare gare gore iroro, Chalamet akaita saHenry V weEngland naTheodore "Laurie" Laurence mumitambo yenguva "Mambo" uye "Vakadzi vadiki", zvichiteerana.