Nyorai kuenderera mberi kweiyi ndima - Mushure mekuhwina menduru dzegoridhe nhanhatu pa1999 European Championships, Van den Hoogenband aive mumwe wevanodiwa pa2000 Summer Olympics, asi vavengi vake vaive vanotyisa. Mumakwikwi emamita 200 akasununguka akatarisana nomuridzi wenyika, muduku weAustralia Ian Thorpe, aidiwa nevanhu vomunharaunda muSydney. Mumakwikwi ekupedzisira, Van den Hoogenband akaisa rekodhi yenyika itsva, asi Thorpe akapindura nenguva 0.02 s chete. Mumutambo wokupedzisira unofadza, Van den Hoogenband akaenzana nenguva yake kubva mumutambo wokupedzisira kuti akunde menduru yegoridhe. Mumakwikwi emamita 100 akasununguka
, Van den Hoogenband zvakare akaisa rekodhi yenyika mumasemi-fainari uye akakunda menduru yake yechipiri yegoridhe, achikunda 1992 na1996 mukwikwidzi, Alexander Popov. Nhoroondo yake yenyika yemamita zana yakamira kusvika 21 Kurume 2008 uye yakaputswa neFrance Alain Bernard (47.60). Van den Hoogenband akahwina mimwe menduru mbiri, mbiri dzendarira, mumakwikwi emamita makumi mashanu akasununguka uye mumakwikwi e4 × 200 m akasununguka, umo aive mutambi wekupedzisira.