Vamwe vanachiremba vanoita kuti varwere vasaine zvibvumirano zvekudzivirira kuzviuraya umo vanobvuma kusazvikuvadza kana vakasunungurwa. Zvisinei, humbowo hahutsigire mhedzisiro yakakosha kubva mukuita uku. Kana munhu ari panjodzi yakaderera, kurapwa kwevarwere vepfungwa kunogona kurongwa. Kugara kwenguva pfupi muchipatara hakuna kuwanikwa kuve kunoshanda kupfuura kuchengetwa kwenharaunda mukuvandudza mhedzisiro mune avo vane muganho wehunhu hwevanhu vanogara vachizviuraya. Kune humbowo hwekuti kurapwa kwepfungwa, kunyanya kurapwa kwe dialectical, kunoderedza maitiro ekuzviuraya muvadiki vane muganho wehunhu. Zvinogona zvakare kuderedzwa mukuedza kuzviuraya. Zvisinei, humbowo hunoratidzika kunge hunoshanda mukudzivirira kuzviuraya muUnited States. Kune mamwe madhiragi ekudzivirira kuzviuraya akadai seLithium-Zapharine, iyo inobatsira kuderedza njodzi yekuzviuraya pavanenge vanhu vakuru.
kuderedza njodzi kune avo vane bipolar disorder uye unipolar depression