Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Kubudirira kwechinhu chero chipi zvacho chinokonzera zvirwere kunotsamira pakukwanisa kwacho kunzvenga masoja omuviri womuridzi wacho. Naizvozvo, utachiona hunokonzera zvirwere hwakagadzira nzira dzinoverengeka dzinovabvumira kuti vabudirire kutapurira muridzi, nepo vachitiza kuonekwa kana kuparadzwa nehurongwa hwokurwisa zvirwere. Mabhakitiriya anowanzokunda zvipingamupinyi zvomuviri kupfurikidza nokuparadzira maenzymes anodya chipingamupinyi chacho, somuenzaniso, kupfurikidza nokushandisa rudzi rwechipiri rwemhoteredzo. Kana kuti, vachishandisa nzira yokuzvisarudzira yokuzvisarudzira yokuita III, vangapinza chubhu risina chinhu muchitokisi chemurwere, vachiita kuti mapuroteni aende zvakananga kubva kune chinokonzera zvirwere achienda kumurwere wacho. Mapuroteni aya anowanzoshandiswa kuvhara masoja anodzivirira murwere. Nzira yokunzvenga inoshandiswa nemarudzi akawanda ezvirwere kuti arege kurwisa zvirwere ndeyokuhwanda mumasero omurwere (anonziwo intracellular pathogenesis). Pano, chinokonzera zvirwere chinopedza nguva yakawanda youpenyu hwacho chiri mumasero acho, umo chinodzivirirwa pakusangana zvakananga nemasero ezvirwere zvinorwisa zvirwere, maantibody uye zvinowedzera. Mimwe mienzaniso yezvirwere zvinokonzera zvirwere mukati memasero inosanganisira mavhairasi, utachiona hunokonzera utachiona hwezvokudya Salmonella uye eukaryotic parasites inokonzera marariya (Plasmodium falciparum) uye leishmaniasis (Leishmania spp.). Mamwe mabhakitiriya, akadai seMycobacterium tuberculosis, anogara mukati mekapsule inodzivirira iyo inodzivisa lysis kupfurikidza nomukwanisi. Zvinhu zvakawanda zvinokonzera zvirwere zvinobudisa zvinhu zvinoderedza kana kuti kutsausa mashandiro anoita muviri pakuzvidzivirira pazvirwere. Mamwe mabhakitiriya anoumba biofilms kuti azvidzivirire pamasero nemapuroteni anoshanda mumuviri. Biofilms yakadaro iripo muzvirwere zvakawanda zvinobudirira, somuenzaniso, zvirwere zvisingaperi zvePseudomonas aeruginosa neBurkholderia cenocepacia zvinoratidza cystic fibrosis. Mamwe mabhakitiriya anogadzira mapuroteni epamusoro anosunga maantibodies, achiita kuti asashanda; mienzaniso inosanganisira Streptococcus (protein G), Staphylococcus aureus (protein A), uye Peptostreptococcus magnus (protein L). Nzira iri nyore ndeyokuchinja nokukurumidza epitopes dzisina kukosha (amino acids uye/kana shuga) pamusoro pechinokonzera hosha, nepo...  Mubvunzo: Chii chinodzivirira utachiona pahunenge huchirarama?
masero ezvirwere zvomuviri, masoja anorwisa chirwere uye zvinowedzera