Pedzisa mutsara unotevera: Somuchinda anotonga weNetherlands akaita Brussels, uye muzinda weCoudenberg zvikurukuru, somusha wake mukuru nedare: ikoko, akazivisa nhaka dzake muna 1515 uye akazivisa kubvisa kwake muna 1555. Somutongi weSpain akagara nhaka zvinhu zveCrown yeAragon kumaodzanyemba kweItaly, uye akabvumidza kukunda kweCastillan conquistadores: Hernán Cortés akabatanidza vaAztec uye akaisa pasi peMiddle America zvichitevera
Kuwa kweTenochtitlan, uye Francisco Pizarro akakunda vaInca ndokutambanudzira kutonga kwechikoloni kuSouth America pashure peHondo yeCajamarca. SaMambo weRoma Tsvene akakwanisa kudzivirira nzvimbo dzake dzeGermany muAustria kubva kumaOttoman aSuleiman the Magnificent (Kukombwa kweVienna) nenzvimbo dzake dzeItaly muDuchy yeMilan kubva kuFrance yaFrancis I (Hondo yePavia): kutsigira mari yeOttoman-Habsburg Hondo uye Hondo dzeItaly Humambo hwakashandisa zvakanyanya goridhe nesirivheri zvinobva kuAmerica. Zvisinei, kuyerera uku kwezvinhu zvinokosha, kwakanga kuriwo chikonzero chokuwedzera kwemari. Charles V akabvumidzawo kutongwa kweAmerica neGermany uye akatsigira nemari rwendo rwomutsvakurudzi Magellan rwokupoterera pasi rose. Asingakwanisi kuumba umambo hwenyika yose uye kudzivisa kuwedzera kwechiPurotesitendi, Charles V akazivisa kurega kwake basa. Kuregera kwake chigaro kwakakamura nzvimbo dzake pakati pemwanakomana wake Philip II weSpain, uyo akatora nzvimbo dzekoloni, uye munun'una wake Ferdinand weAustria, Bohemia neHungary uyo akatora Humambo Hutsvene hweRoma. Netherlands yeHabsburg neDuchy yeMilan zvakaramba zviri chikamu cheHoly Roman Empire, asi zvakasiyiwawo mubatanidzwa wevanhu naMambo weSpain.