Pedzisa mutsara unotevera: Heche akaonekwa mumutambo muduku-diki "Upenyu hwepabonde" (2005), achirondedzera upenyu hwemazuva ano hworudo uye achitamba pamwe chete naAzura Skye naElizabeth Banks. Firimu racho rakaratidzwa mumutambo wemufirimu uye rakagamuchira kuratidzwa kweterevhizheni. Muna 2006 Heche akatanga kushanda pachake akatevedzana, "Varume vari Miti". Muchiratidziro, akabata semunyori weNew York, uyo mushure mekuziva kuti mukomana wake ari kumubiridzira, anotamira kuguta diki muAlaska, iro rinoitika kuve rakawanda nevarume vasina kuroora uye vakadzi vashoma. "Varume vari Mumiti" vakadzimwa muna May 2008, pashure penguva yakapfupikiswa ne
kurova kwavanyori. Munguva yekuratidzwa kwechiratidziro, Heche akabata nyeredzi mune inotyisa-komedhi "Kutambura Kwemunhu Charity" (2007), iyo yerudo komedhi "Chii Rudo" (2007), uye sainzi-fungidziro inonakidza "Toxic Skies" (2008), ese ayo akaenda zvishoma-akaonekwa nevateereri.