Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Passage: The cyclol hypothesis ndiyo muenzaniso wokutanga wokugadzirwa kwepuroteni yakapetwa, yeglobular. Yakagadzirwa naDorothy Wrinch mukupera kwema1930, uye yakavakirwa pafungidziro nhatu. Chokutanga, fungidziro yacho inofungidzira kuti mapoka maviri epeptide anogona kubatanidzwa ne cyclol reaction (Figure 1); idzi crosslinks covalent analogues yevasiri-covalent hydrogen bonds pakati pemapoka epeptide. Kuita uku kwakacherechedzwa muergopeptides nemamwe makemikari. Chechipiri, inofungidzira kuti, pasi pemamiriro ezvinhu akati, amino acids achaita zvakasikwa huwandu hwakawanda hunobvira hwecyclol crosslinks, zvichiguma nemamolecule ecyclol (Figure 2) uye machira ecyclol (Figure 3). Aya mamorekuru ecycloal nemicheka hazvina kumboonekwa. Pakupedzisira, fungidziro yacho inofungidzira kuti mapuroteni eglobular ane chimiro chechitatu chinoenderana nePlatonic solids uye semiregular polyhedra yakaumbwa nemicheka ye cyclol isina mahombekombe akasununguka. Mamorekuru akadaro e"cyclol akavharwa" haanawo kuonekwa.  Mubvunzo: Rudzii rwokuita runobatanidza mapoka maviri epeptide?
cyclol