Pedzisa mutsara unotevera: Mangano akapinda Manual Training High School, New York Prep, uye St. John's College. Aiva nhengo yePhi Sigma Chi uye yeClub yeVashandi. Pakutanga akaenda kunoshanda muimba yababa vake inoitirwa mariro. Muna 1934, akasarudzwa kuNew York State Assembly seDemocrat, achimiririra Kings County 8th District. Akashanda muGungano muna 1935, 1936, uye 1937. Akanga ari nhume yokuchinjana muDemocratic National Convention ya1936, uye aizoshanda senhume yeDemocratic National Convention ya1940,
Kokorodzano Dzemarudzi dzeDemocratic dza1956, 1960, uye 1964. Muna 1937, akasarudzwa kuva Sheriff weKings County. Akashanda saSheriff kubva muna 1938 kusvika muna 1941. Muna 1941, akasarudzwa senhengo yeNew York State Democratic Committee. Muna 1942, chinzvimbo cheSheriff weKings County chakabviswa ndokutsiviwa nemumwe chete, sheriff weguta rose, achimuita Sheriff wekupedzisira weKings County.