Pedzisa mutsara unotevera: Pashure pokurwira rusununguko, Gavhuna mutsva anofambira mberi weBuenos Aires, Martín Rodríguez, akagadza Pergamino kuva Mutongi woRugare muna 1822 uye chikoro chokutanga chakavhurwa muna 1828. Guta racho rakakurumidza kuva musha wezvipembenene zvakawanda uye zvichitevera kusimuka kwa1829 kweGavhuna Juan Manuel de Rosas (ane zvido zvemhuri zvaive zvakatenderedza kufudza mombe) mubatanidzwa wepedyo wakagadzirwa pakati pagavhuna nemhuri dzePergamino dzakakurumbira, maAcevedos nemaAnchorenas; hurumende yaRosas yekudzvinyirira, zvisinei, yakaguma nekuvharwa kwechikoro chega muna 1838. Kutevera Gavhuna Rosas'
Muna 1852, vakuru vakuru vomunzvimbo yacho vakabatana naBartolomé Mitre, mutsigiri akakurumbira akamirira dunhu reBuenos Aires kuti awane kuzvitonga kuzere. Mitre akasarudzwa gavhuna muna 1860 uye Mutungamiri weArgentina muna 1862. Kugadzwa muna 1862 naPurezidhendi Mitre kwesangano rekutanga reArgentina reAgronomy kwakabatsira kutungamira mukusimudzirwa kwechiitiko chitsva chehupfumi mudunhu rakakomberedza Pergamino: kurima kwakasimba. Kutumirwa kwokutanga kwezviyo zveArgentina kusvika muUnited Kingdom muna 1875 kwakatungamirira kukubudirira mune zvokurima uko kwakaunza kurimwa kukuru kwechibage kuPergamino. Kukura kweguta kwakawedzerazve pakusvika kweCentral Argentine Railway muna 1882, munzira inoenda kuRosario. Pergamino, ane vagari panguva iyoyo vakapfuura 10 000 uye musha wemabhizimisi akanyoreswa anopfuura 90, akasarudzwa zviri pamutemo seguta musi wa 23 October 1895.