Mushure mokunge utachiona hweTB hwapararira, hutachiona hunotanga apo mycobacteria inosvika kumapapu emhepo emapapu, kwavanopinda nekudzokorora mukati me endosomes ye alveolar macrophages. Macrophages anoona hutachiona sechinhu chisingazivikanwe uye vanoedza kuubvisa ne phagocytosis. Munguva iyi, hutachiona hunoputirwa ne macrophage uye hunochengeterwa mune yenguva pfupi-yakasungwa membrane inonzi phagosome, chirwere cheTB. Muvanhu vane HIV, njodzi yekukudziridza TB inoshanda inowedzera kusvika kungangoita 10% pagore. Kana kurapwa kwakanaka kusingapiwe, huwandu hwerufu hwezviitiko zveTB hunosvika 66%.
10% pagore