Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Sechinhu chinoshandiswa pakugadzira zvinhu zvipenyu, ceramide yave ichibatanidzwa mumabasa akasiyana-siyana epanyama anosanganisira apoptosis, kumiswa kwekukura kwemasero, kusiyanisa, kukwegura kwemasero, kutama kwemasero uye kubatana. Basa re ceramide uye metabolites yayo yakaderera yakaratidzwawo mune dzimwe mamiriro ezvinhu ezvirwere zvinosanganisira kenza, neurodegeneration, chirwere cheshuga, microbial pathogenesis, kufutisa, uye kuzvimba. Ceramides inokonzera skeletal muscle insulin resistance kana yakagadzirwa semugumisiro wekugadziriswa kwemafuta akazara eTLR4 receptors. Mafuta asina kuzara haana izvi zvaanoita. Ceramides inokonzera insulin resistance mumasero akawanda nokudzivisa Akt/ PKB signaling. Kuunganidzwa kweLDL cholesterol neceramide kunokonzera kuchengetwa kweLDL mumadziro etsinga, zvichitungamirira kuatherosclerosis. Ceramides inokonzera endothelial dysfunction nokushandisa protein phosphatase 2 (PP2A). Mu mitochondria, ceramide inodzvinyirira ketani inotakura maerekitironi uye inokurudzira kugadzirwa kwemarudzi eoksijeni anoshanda.  Mubvunzo: rudzii rwelipid ndirwo ceramide?
bioactive