Muvanhu vane AD, kuderera kwekudzidza uye kuyeuka kunoguma kwaita kuti vawane chirwere. Muchikamu chiduku, zvinetso nemutauro, mabasa ekunyora, maonero (agnosia), kana kuuraya kufamba (apraxia) zvinonyanya kuzivikanwa kupfuura matambudziko ekuyeuka. AD haibatanidzi zvese zvekuyeuka zvakaenzana. Zviyeuchidzo zvekare zvehupenyu hwemunhu (episodic memory), chokwadi chakadzidziswa (semantic memory), uye chiyeuchidzo chisingazivikanwe (chiyeuchidzo chemuviri pamusoro pekuti ungaita sei zvinhu, sekushandisa forogo kuti udye kana kunwa sei kubva mugirazi) zvinokanganiswa zvishoma pane chokwadi chitsva kana ndangariro. Matambudziko emutauro anonyanya kuzivikanwa nekudzikira kwemashoko uye kuderera kwekutaura, kusvika pakushomeka kwese kwemuromo uye mutauro wakanyorwa. Muchikamu ichi, munhu ane Alzheimer anokwanisa kukurukura zvakanyanya mabasa ekutanga (apraxia) asi anogona kuramba achizviita nekuzvimiririra.
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