Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Passage: Enzyme kinetics ndiyo ongororo yokuti maenzayimu anosunga sei zvinhu zvawo uye anozvichinja kuva zvinhu. Nhamba dzinoshandiswa pakuongorora kinetics dzinowanzotorwa kubva pakuongororwa kwema enzyme. Muna 1913 Leonor Michaelis naMaud Leonora Menten vakagadzira dzidziso yakawanda ye enzyme kinetics, iyo inonzi Michaelis <unk> Menten kinetics. Mupiro mukuru waMichaelis naMenten wakanga uri wokufunga nezvemhinduro dzeenzyme mumatanho maviri. Muchikamu chokutanga, substrate inosunga reversibly kune enzyme, ichiumba enzyme-substrate complex. Iyi dzimwe nguva inonzi Michaelis-Menten complex mukukudza kwavo. Enzyme yacho inobva yaita kuti makemikari aite basa racho obva abudisa chigadzirwa chacho. Iri basa rakavandudzwa naG. E. Briggs naJ. B. S. Haldane, avo vakawana kinetic equations iyo ichiri kushandiswa zvikuru nhasi. Kuti uwane kukurumidza kukuru kwekupindura kweenzymatic, substrate yezvipimo inowedzerwa kusvikira mwero wekugadzirwa kwechigadzirwa uchionekwa. Ikoku kunoratidzwa mukukombama kwekugutsikana kurudyi. Kugutsikana kunoitika nokuti, sezvo substrate kuwanda kunowedzera, zvakawanda zve enzyme yakasununguka zvinoshandurwa kuva substrate-yakasungirirwa ES yakaoma. Pakupindura kwakanyanya (Vmax) kweenzyme, nzvimbo dzese dzinoshanda dzeenzyme dzinosungirirwa kune substrate, uye huwandu hweES yakaoma yakaenzana nehuwandu hwese hweenzyme. Vmax ingori imwe yeanoverengeka akakosha kinetic parameter. Kuwanda kwechinhu chinoshandiswa pakugadzira zvinhu zvinoshandiswa pakugadzira zvinhu kunokoshawo. Izvi zvinopiwa ne Michaelis-Menten nguva dzose (Km), iyo inonzi substrate kuwanda kunodiwa kuti enzyme isvike hafu yekupindura kwayo kwakanyanya; kazhinji, enzyme imwe neimwe ine KM inoratidzirwa kune imwe substrate. Chimwe chinhu chinogara chiripo kcat, inonziwo nhamba yekushandurwa, inova nhamba yemamolekyu e substrate anobatwa nenzvimbo imwe inoshanda pasekondi. Kubudirira kwe enzyme kunogona kuratidzwa maererano ne kcat / Km. Ikoku kunonziwo nguva dzose yokurondedzerwa uye...  Mubvunzo: Rudzii rwezvinhu zvipenyu rwakakwana mune cataytic uye kinetically?
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