Kutevera kurwira rusununguko, Gavhuna mutsva anofambira mberi weBuenos Aires, Martín Rodríguez, akapa Pergamino Mutongi weRunyararo muna 1822 uye chikoro chokutanga chakavhurwa muna 1828. Guta racho rakakurumidza kuva musha wezvipembenene zvakawanda uye zvichitevera kusimuka kwa1829 kweGavhuna Juan Manuel de Rosas (ane zvido zvemhuri zvaive zvakatenderedza kufudza mombe) mubatanidzwa wepedyo wakagadzirwa pakati pagavhuna nemhuri dzePergamino dzakakurumbira, maAcevedos nemaAnchorenas; hurumende yaRosas yekudzvinyirira, zvisinei, yakaguma nekuvharwa kwechikoro chega muna 1838. Pashure pokunge Gavhuna Rosas amutswa muna 1852
, vakuru vakuru vomunzvimbomo vakazvibatanidza naBartolomé Mitre, mutsigiri akatanhamara akamirira Province yeBuenos Aires nokuda kwokuzvitonga kuzhinji. Mitre akasarudzwa gavhuna muna 1860 uye Mutungamiri weArgentina muna 1862. Kugadzwa muna 1862 naPurezidhendi Mitre kwesangano rekutanga reArgentina reAgronomy kwakabatsira kutungamira mukusimudzirwa kwechiitiko chitsva chehupfumi mudunhu rakakomberedza Pergamino: kurima kwakasimba. Kutumirwa kwokutanga kwezviyo zveArgentina kusvika muUnited Kingdom muna 1875 kwakatungamirira kukubudirira mune zvokurima uko kwakaunza kurimwa kukuru kwechibage kuPergamino. Kukura kweguta kwakawedzerazve pakusvika kweCentral Argentine Railway muna 1882, munzira inoenda kuRosario. Pergamino, ane vagari panguva iyoyo vakapfuura 10 000 uye musha wemabhizimisi akanyoreswa anopfuura 90, akasarudzwa zviri pamutemo seguta musi wa 23 October 1895.