Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Varume vane chirwere cheDown syndrome kazhinji havabereki vana, nepo vakadzi vane mwero wakaderera wokubereka kana uchienzaniswa neavo vasina. Fertility inofungidzirwa kuva iripo mu30~50% yevakadzi. Nguva yokuguma kuenda kumwedzi inowanzoitika pazera duku zvikuru. Kusabereka zvakanaka kwevarume kunofungidzirwa kuti kunokonzerwa nezvinetso zvokukura kwembeu; zvisinei, kungavawo kwakabatana nokusava vanoshingaira muvatano. Kubva muna 2006, varume vatatu vane chirwere cheDown syndrome vakabereka vana uye vakadzi 26 vakabereka vana. Pasina nzira dzokubatsira kubereka nadzo, inenge hafu yevana vomunhu ane chirwere cheDown syndrome ichavawo nechirwere ichi.  Mubvunzo: Varume havawanzobereka vana kana vaine chirwere chipi?
Chirwere cheDown