Pedzisa mutsara unotevera: Assertio Therapeutics yakambova neNucynta ER neNucynta IR. Musi waNdira 15, 2015, Depomed yakazivisa kuwanikwa kweTapentadol ((Nucynta) franchise kubva kuJanssen Pharmaceutica nemari. Chibvumirano chakavharwa musi waApril 2, 2015, uye zvigadzirwa zvakatangazve muna June 2015 mushure mekuwedzera kukuru kwevashandi vekutengesa. Pashure
Hurricane Maria muna 2017 kambani yakatarisana nekushomeka kukuru kwemushonga uyu nekuda kwenzvimbo yekugadzira nzvimbo muPuerto Rico. Muna Ndira 2018, mushure memakore asingasviki matatu, kodzero dzekugadzira dzeNucynta dzakatengeswa pamadhora gumi emamiriyoni emadhora uye nemadhora mazana matatu nemakumi matatu nemashanu emadhora emadhora emakore mana ekutanga. Tapentadol zvino inogadzirwa nokuda kwemusika weUnited States neCanada neCollegium Pharmaceutical.