Pedzisa mutsara unotevera: Pashure peHondo yeOpium Yokutanga uye kugadzwa kweHong Kong, Macau yakarasikirwa nebasa rayo sedoko guru. Kugadzirwa kwemarasha nezvinonhuwira, pamwe chete nokugadzirwa kwetii nefodya, zvaikosha zvikuru munharaunda yacho panguva iyi. Portugal yakakwanisa kushandisa kushaya simba kweChina mushure mehondo uye kusimbisa hutongi hwayo; Gavhuna weMacau akatanga kuramba kubhadhara China rendi yepasi yegore negore yekoloni muma1840, uye akabatanidza Taipa neColoane, muna 1851 na1864. Portugal yakatorawo Lapa neMontanha zvaiva pedyo, asi izvi zvaizodzorerwa kuChina na1887, apo kodzero dzokugara nokusingaperi pamusoro peMacau dzakagadziriswa muChinese-Portuguese Treaty yePeking. Chibvumirano ichi chakarambidzawo Portugal kubvisa Macau pasina kubvumirwa neChina. Pasinei zvapo nekurwisana kwaiitika pakati pemasimba eCanton nehurumende yekoloni, chinzvimbo cheMacau chakaramba chisina kuchinjwa kuburikidza neshanduko dzorusununguko dzevaviri
Portugal muna 1910 uye China muna 1911. Kuomintang yakasimbisazve kutonga kwePortugal muMacau apo Chibvumirano chePeking chakatauriranazve muna 1928.