Pfupisa nyaya yacho:  Mukombe miviri bedzi yekofi pazuva inogona kuderedza nehafu ngozi yekenza yemazamu inodzoka muvakadzi vanopora kubva kuchirwere chacho, kuongorora kwakawana kudaro. Vatsvakurudzi vakawana kuti kofi inogona kumisa kukura kwemamota muvakadzi vakamborapwa nomushonga unonzi tamoxifen. Tamoxifen ndiyo mushonga mukuru unorapa nemahormone unopiwa vakadzi vasati vapinda nguva yokuguma kuenda kumwedzi, uye unowanzotorwa kwemakore mashanu kana kupfuura pashure pokurapwa kenza yemazamu. Vanzveri vakawana kuti makapu maviri bedzi ekofi pazuva anogona kuderedza nehafu ngozi yekenza yemazamu inodzoka uye inowedzera kushanda kwemushonga unonzi tamoxifen. Zvirwere zvakawanda zvegomarara repazamu zvinovimba nehomoni inonzi estrogen kuti ikure, uye tamoxifen inodzivisa kuti estrogen isasvika kumasero ekenza. Izvi zvinoreva kuti kenza yacho inokura zvishoma nezvishoma kana kuti inomira kukura zvachose. Sechikamu chechidzidzo chacho, vatsvakurudzi vokuSweden nevokuBritain vakaongorora mashoko evarwere 1090 vaiva nekenza yemazamu, vachitevera imwe ongororo yakaitwa makore maviri apfuura. Vakawana kuti vakadzi vanopfuura 500 vakanga varapwa neTamoxifen, uye avo vakanga vanwa makapu maviri ekofi pazuva, vakanga vane ngozi yehafu bedzi yokudzoka kwekenza yavo kupfuura avo vakanga vanwa kofi shoma, kana kuti kwete chose chose. Ann Rosendahl, muongorori wepaLund University akaita ongororo yacho, akati: 'Tsvakurudzo yacho inoratidzawo kuti vaya vanonwa makapu maviri ekofi pazuva vane tumarara tuduku uye vashoma vane tumarara tunoenderana nemahomoni. 'Takaona kuti izvi zvakanga zvatoitika panguva yokuongororwa.' Vatsvakurudzi vakanyatsoongororawo zvinhu zviviri zvinowanzovapo mune kofi - caffeine necaffeic acid. Vakawana kuti masero ekenza yemazamu aiita chimwe chinhu pazvinhu izvi, zvikurukuru caffeine. Caffeine yakaita kuti masero aparadzane kashoma, uye afe kakawanda, zvikurukuru apo yakanwiwa pamwe chete ne tamoxifen. Chidzidzo chacho chakawana kuti caffeine yakaita kuti masero ekenza yemazamu aparadzane kashoma uye afe kakawanda. Amai Rosendahl vakati: "Izvi zvinoratidza kuti zvinhu izvi zvine zvazvinoita pamasero ekenza yemazamu uye zvinodzima nzira dzokuratidza kuti...
Kofi inogona kudzivisa kenza kudzoka muvakadzi vanorapwa ne tamoxifen. Tamoxifen inodzivisa estrogen kusvika kumasero emudumbu, saka haawedzeri. Vanonwa kofi vaiva nekenza shoma uye mamota avo aiva maduku. Caffeine inoderedza nzira dzokuratidzira idzo masero ekenza anoda kuti akure.