Vanotsvakurudza vanodzidza abiogenesis kuburikidza nemubatanidzwa wemamolecular biology, paleontology, astrobiology, oceanography, biophysics, geochemistry uye biochemistry, uye vanovavarira kuona kuti ma pre-hupenyu makemikari maitiro aya akaita sei kuti hupenyu huvepo. Kuongororwa kweabiogenesis kunogona kuve geophysical, kemikari, kana bhayoroji, nemaitiro achangoburwa kuyedza synthesis yevatatu vese, sezvo hupenyu hwakamuka pasi pemamiriro ezvinhu akasiyana zvakanyanya kubva kune ari pasi pano nhasi. Hupenyu hunoshanda kuburikidza neakasarudzika makemikari e kabhoni nemvura uye inovaka zvakanyanya pamhuri ina dzakakosha emakemikari: lipids (mafuta maseru maseru), carbohydrates (mashuga, cellulose), amino acids (protein metabolism), uye nucleic acids (self-replicating DNA uye yakabudirira RNA). Chero dzidziso yematangiro uye makirasi emakemikari epakati ehupenyu aya akaunza sei hupenyu.
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