Musi waNovember 2, 1962, Kennedy akataura neUnited States kuburikidza neredhiyo uye terevhizheni nhepfenyuro maererano nehurongwa hwekubvisa maSoviet R-12 missile bases iri munzvimbo yeCaribbean. Ngarava dzakabva kuCuba musi waNovember 5 kusvika 9. US yakaita cheki yekupedzisira yekuona sezvo imwe neimwe yengarava yakapfuura mutsetse wekudzivirira. Kuenderera mberi kwekuedza kwekudyidzana kwakatarisirwa kubvisa mabhomba eSoviet Il-28, uye akatakurwa mungarava nhatu musi waDecember 5 na6. Panguva imwecheteyo nekuzvipira kweSoviet paIl-28s, hurumende yeUS yakazivisa kupera kwekudzivirira kubva na6: 45 pm EST musi waNovember 20, 1962. Panguva iyo Kennedy aifunga kuti Missile Crisis yakagadziriswa pazvikepe zvisereere zveSoviet Union muItaly.
Cuba