Carson akanga asangana naBarack Obama muna 2004 apo vose vari vaviri vakanga vakasarudzwa neDemocratic Party nokuda kwezvigaro zvakasununguka muUnited States Senate. Carson akatsigira Obama muna 2006 nokuda kwesarudzo yemutungamiri wenyika ya2008. Carson akashanda semumiriri waObama pachake mukubvumidzwa kwevanokwikwidza kuti vave nhume kubva kuOklahoma kuenda ku2008 Democratic National Convention
. Oklahoma ndiyo yakanga iri nyika yokutanga kududza boka rayo rose rokuDemocratic Convention ra2008.