Pedzisa mutsara unotevera: Muna January 2008, McCaskill akatsigira panguva iyoyo Seneta Barack Obama mu
mushandirapamwe wake wokusarudzwa kweDemocratic kuti ave purezidhendi, achimuita mumwe wevaSenator vokutanga kuita kudaro. Akanga ari mumwe wezviso zvaioneka zvikuru mukushandira kwake, uye kutsigirwa kwake kwakanga kwakakosha kukunda kwaObama kwakakomba mumasarudzo ekutanga eMissouri munaFebruary 2008. Akati mwanasikana wake Maddie ndiye akamunyengetedza kuti atsigire pachena Obama. Aiwanzotaurwa nezvake somunhu aigona kuzova mutevedzeri wemutungamiri wenyika waObama, asi haana kumbobvira afungwa nezvazvo. Akataura pazuva rokutanga reDemocratic National Convention muna August 2008.