Nzira inonyanya kuzivikanwa ye chromosomal crossover ndeye homologous recombination, apo ma chromosomes maviri anobatanidzwa anogoverana zvakafanana zvakafanana. Kwete-homologous recombination inogona kukuvadza masero, sezvo inogona kubudisa chromosomal translocations uye genetic abnormalities. Kugadziriswa kwekugadziriswa kunokonzerwa nema enzymes anozivikanwa se recombinases, akadai seRAD51. Nhanho yekutanga yekugadziriswa kwekugadziriswa kwechipiri inokonzerwa nekugadziriswa kwekugadziriswa kweDNA nekuguma kweDNA kana kumadokero.
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