Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: PWS inokonzerwa neepigenetic phenomenon inozivikanwa se imprinting, inokonzerwa nekubviswa kwemakopi ababa e SNRPN uye NDN necdin genes pamwe chete nemapoka e snoRNAs: SNORD64, SNORD107, SNORD108 uye makopi maviri eSNORD109, makopi 29 eSNORD116 (HBII-85) uye makopi 48 eSNORD115 (HBII-52). Izvi zviri pa chromosome 15 iri munharaunda 15q11-13. Iyi nharaunda inonzi PWS/AS inogona kurasikirwa neimwe yenzira dzinoverengeka dzokuberekwa nadzo, idzo muzviitiko zvizhinji dzinoitika kupfurikidza neshanduko yengozi. Dzimwe nzira dzisingawanzowaniki dzinosanganisira uniparental disomy, shanduko dzisingawanzoitiki, kushandurwa kwechromosome, uye kubviswa kwegen. Nemhaka yokudhinda, makopi anogarwa nhaka naamai eaya majini anenge asingaiti, uye makopi ababa bedzi eaya majini anoratidzwa. PWS inobva pakurasikirwa nemakopi ababa munharaunda iyi. Kubviswa kwenharaunda imwe chete yacho pa chromosome yaamai kunokonzera chirwere cheAngelman (AS). PWS neAS zvinomiririra zviitiko zvokutanga zvakashumwa zvokupararira kwezvirwere muvanhu.  Mubvunzo: Chii chinokonzera PWS?
chiitiko chinozivikanwa sokupinda