Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Nzira chaiyo inokonzera chirwere cheshuga chevakadzi vane pamuviri haisati yazivikanwa. Chiratidzo cheGDM ndiko kuwedzera kwekudzivirira insulin. Mahormone okubata pamuviri nezvimwe zvinhu zvinofungidzirwa kuti zvinokanganisa mashandiro anoita insulin sezvo ichisunga kune insulin receptor. Zvichida kupindira kwacho kunoitika padanho rechiratidzo chemasero chinopfuura chinogamuchirwa ne insulin. Sezvo insulin ichibatsira kuti glucose ipinde mumasero akawanda, insulin resistance inodzivisa kuti glucose ipinde mumasero zvakanaka. Somugumisiro, glucose inoramba iri muropa, uko mwero weglucose unokwira. Insulin yakawanda inodikanwa kuti ikurire kusadzivirira uku; inenge 1.5 kusvika ku2.5 nguva yakawanda insulin inogadzirwa kupfuura muhurume hwakanaka. Kusadzivirira insulin chinhu chinowanzoitika chinomuka muchikamu chechipiri chemuviri, icho muzviitiko zveGDM chinofambira mberi kubva ipapo kusvika kumatanho anoonekwa mumunhu asina pamuviri ane chirwere cheshuga chechipiri. Kunofungidzirwa kuti kunochengetedza kugoverwa kweglucose kumwana ari kukura. Vakadzi vane GDM vane insulini isingagadziriswi iyo yavasingagoni kuenzanisa nokugadzirwa kwakawedzerwa mumasero-beta epanyama. Mahormone eplacental, uye, kusvika pamwero muduku, kuwanda kwemafuta mukati mokubata pamuviri, kunoratidzika kuva kunopindira mukudzivisa insulin mukati mokubata pamuviri. Cortisol neprogesterone ndizvo zvinonyanya kukonzera, asi lactogen yomunhu, prolactin uye estradiol zvinobatsirawo. Multivariate stepwise regression analysis inoratidza kuti, pamwe chete nemamwe mahormone eplacental, leptin, tumor necrosis factor alpha, uye resistin zvinobatanidzwa mukuderedzwa kwekunzwa insulin kunoitika panguva yekuzvitakura, ne tumor necrosis factor alpha inonzi ndiyo yakasimba yakazvimirira yekufungidzira kwekunzwa insulin panguva yekuzvitakura. Kuwirirana kwakapesana nokuchinja kwokunzwa insulin kubva nguva isati yasvika yokubata pamuviri kusvikira kunhambo yokupedzisira yokubata pamuviri kunogovera inenge hafu yemisiyano mukuderedzwa kwokunzwa insulin mukati mokubata pamuviri: namamwe mashoko, mwero wakaderera kana kuchinja kwezvinhu zveTNF alpha zvinotsinhirana netarisiro huru, kana kuti kugadzirirwa, kurwisa insulin kana kuti...  Mubvunzo: Ndechipi chirwere chinoitika mukati mechikamu chechipiri chokubata pamuviri?
Kurwisa insulin