Muna 1966, Tony akaroora muchengeti wemba wemhuri Joan Gustafson. Vaive nevana vaviri, Jennifer naMario. Madonna akatsamwira baba vake nekuroorazve, ndokutanga kumumukira, izvo zvakatambudza hukama hwavo kwemakore mazhinji mushure meizvozvo. Akaenda kuSt. Frederick neSt. Andrew's Catholic Elementary Schools, uye West Middle School. Madonna aizivikanwa nezera rake repamusoro, uye akawana mukurumbira nekuda kwehunhu hwake husina kujairika. Aizoita ngoro dzekutengesa uye maoko emaoko mumakoridho pakati pemakirasi, akaturika nemabvi ake kubva kumabhawa emonkey panguva yekuzorora, uye akasimudza siketi yake yese panguva yekirasi kuitira kuti vakomana vaone mbatya dzake dzemukati. Baba vaMadonna vakaisa piyano yake muzvidzidzo zvechinyakare, asi akazomugombedzera kuti abvumire basa rake rekutamba kutora zvidzidzo zvishoma zveballet.
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