Kana vanhu vakagovana magene uye mamiriro ezvakatipoteredza, avhareji yekureba inowanzo kuve yakasarudzika mukati meboka. Kusiyana kwakasarudzika kwehurefu (kutenderera 20% kutsauka kubva paavhareji) mukati mehuwandu hwakadai dzimwe nguva kunokonzerwa ne gigantism kana dwarfism, izvo zvinokonzerwa nemajini chaiwo kana kusagadzikana kwe endocrine. Kureba kwevanhu kunogona zvakare kushanda sechiratidzo chehutano hwehutano hwehutano, mhando yekenza uye kushoma kuwana kenza. Yunivhesiti yeHawaii yakawana kuti iyo "hupenyu hurefu gene" FOXO3 iyo inoderedza mhedzisiro yekukwegura inowanzo kuwanikwa muvanhu vane diki saizi yemuviri. Kureba kupfupi kunoderedza njodzi yekushomeka kwemutsipa. Kana vanhu vakagovana magene uye mamiriro ezvakatipoteredza, avhareji yekureba inowanzo kuve yakasarudzika mukati meboka.
ukuru kana kuti huduku