Hepburn akaonekwa mumafirimu mashoma sezvo hupenyu hwake hwakaenderera mberi, achipa yakawanda yehupenyu hwake hwekupedzisira kuUNICEF. Akanga abatsira kusangano kubva muna 1954, akabva ashanda mune dzimwe nharaunda dzine hurombo muAfrica, South America, neAsia pakati pa1988 na1992. Akapihwa Presidential Medal of Freedom mukucherechedza basa rake seMumiriri weUNICEF Goodwill muna Zvita 1992. Mwedzi mumwe gare gare, Hepburn akafa nekenza yeappendix kumba kwake kuSwitzerland aine makore makumi matanhatu nematatu.
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