Zvinhu izvi zvinogona kukuvadza zvinonzi xenobiotics. Xenobiotics dzakadai semishonga yekugadzira, chepfu dzepanyama uye mishonga inorwisa mabhakitiriya inoiswa muchetura neseti ye xenobiotic-metabolizing enzymes. Muvanhu, izvi zvinosanganisira cytochrome P450 oxidases, UDP-glucuronosyltransferases, uye glutathione S-transferases. Iyi sisitimu ye enzymes mumatanho matatu inotanga oxidize xenobiotic (phase I) uyezve inosangana nemvura-inogadziriswa mamorekuru (phase II). Aya makemikari anogadziriswa mvura-inogadziriswa xenobiotic anogona kutorwa kunze kwemasero e xenobiotic uye anogona kutorwa kunze mumasero e xenobiotic uye anowedzerwa neakagadziriswa maseru e xenobiotic-metabolizing enzymes.
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