Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Dzidziso pamusoro pokuvirisa ropa dzave dziripo chifo chenguva yekare. Muongorori womuviri womunhu Johannes Müller (1801<unk>1858) akarondedzera fibrin, chinhu chinogadzira thrombus. Chinhu chayo chinogadziriswa, fibrinogen, nokudaro chakatumidzwa zita raRudolf Virchow (1821<unk>1902), uye chakaparadzaniswa nemakemikari naProsper Sylvain Denis (1799<unk>1863). Alexander Schmidt akataura kuti kushandurwa kubva ku fibrinogen kuenda ku fibrin imhedzisiro yechiitiko che enzymatic, uye yakanyora enzyme yekufungidzira "thrombin" uye mutangiri wayo "prothrombin". Arthus akawana muna 1890 kuti karusiyamu inokosha pakuita kuti ropa rigwambe. Maplatelet akaonekwa muna 1865, uye basa rawo rakarondedzerwa naGiulio Bizzozero muna 1882. Dzidziso yokuti thrombin inogadzirwa nokuvapo kwechimwe chinhu chinonzi tissue factor yakasimbiswa naPaul Morawitz muna 1905. Panguva ino, zvaizivikanwa kuti thrombokinase/thromboplastin (chinhu III) inobudiswa nemasero akakuvara, ichipindirana neprothrombin (II), iyo, pamwe chete necalcium (IV), inoumba thrombin, iyo inoshandura fibrinogen kuva fibrin (I).  Mubvunzo: Muller akararama rini?
1801<unk>1858