Messi akavhura mwaka wa2015-16 nekurova kaviri kubva pakurova pachena muBarcelona 5-4 (mushure mekuwedzera nguva) kukunda Sevilla muEFAFA Super Cup
. Musi wa16 Gunyana, akazova mutambi wechidiki kuita 100 kuoneka muEFAFA Champions League mune 1<unk>1 kure dhirowa kuRoma. Mushure mekukuvara kwebvi, akadzokera kunhandare musi wa21 Mbudzi, achiita chinzvimbo mukukunda kweBarcelona 4-0 kure nemukwikwidzi weReal Madrid mu "El Clásico". Messi akapedzisa gore racho nekukunda 2015 FIFA Club World Cup Final musi wa20 Zvita, achiwana mukombe wake wechishanu we2015 apo Barcelona yakakunda River Plate 3<unk>0 muYokohama. Musi wa 30 Zvita, Messi akarova mumutambo wake wechi500 kuBarcelona, mumutambo wavakakunda Real Betis 4-0.