Muzvinafundo wechiremba wechiChirungu wezana ramakore rechi19 Sydney Ringer akagadzira munyu une chloride yesodium, potassium, calcium nemagnesium yakakodzera kuchengetedza kurova kwemoyo wemhuka yakasarudzika kunze kwemuviri. Muna 1885, Wilhelm Roux akabvisa chikamu cheplate medullary ye embryonic huku uye akaichengeta mune inodziya saline solution kwemazuva akati wandei, achimisikidza musimboti wehutachiona hwehutachiona. Ross Granville Harrison, achishanda kuJohns Hopkins Medical School uyezve kuYale University, akaburitsa mhedzisiro yezvaakaedza kubva muna 1907 kusvika 1910, achimisikidza nzira yekurima tishu. Maitiro ekurima maseru akafambira mberi zvakanyanya muma1940 nema1950 kutsigira kutsvagisa muvirology. Kukura mumasero ekurima kwakabvumidza kugadzirwa kwemasero akacheneswa ekugadzira majekiseni.
1885