Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: Rimwe basa rinokosha retsinga dzinorwisa utachiona nderokuziva nokubvisa mamota. Ikoku kunonzi kuongorora kwokurwisa utachiona. Masero emamota akachinjwa anobudisa maantigen asingawaniki mumasero akajairika. Kumuviri, maantigen aya anoita seasingazivikanwi, uye kuvapo kwawo kunoita kuti masero omuviri arwise masero emudumbu anenge achinja. Maantigen anoratidzwa nemamota ane manyuko akati wandei; mamwe anobva kumavhairasi eoncogenic akaita sehutachiona hwepapillomavirus yemunhu, inokonzera kenza yemuromo wechibereko, nepo mamwe ari mapuroteni emuviri chaiwo anoitika pamwero wakaderera mumasero akajairika asi anosvika pamwero wakakwirira mumasero emamota. Mumwe muenzaniso inonzi enzyme inonzi tyrosinase iyo, apo inoratidzirwa mumwero mukuru, inoshandura masero edehwe akati (semuenzaniso melanocytes) kuva mamota anonzi melanomas. Chimwe chinhu chechitatu chinogona kukonzera kuti tumori dzive nemaantigen mapuroteni anowanzokosha kuti masero arambe achikura uye achirarama, ayo anowanzoshanduka kuva mamolekyu anokonzera kenza anonzi maoncogenes. Chinhu chikuru chinoitwa nemuviri pakurwisa zvirwere ndechokuparadza masero asina kunaka uchishandisa masero anonzi T anouraya, dzimwe nguva achibatsirwa nemasero anonzi T anobatsira. Maantigen ehutachiona anoratidzwa pamamorekuru eMHC kirasi I nenzira yakafanana neantigens eutachiona. Izvi zvinobvumira masero eT anouraya kuti azive kuti sero renzungu harina kurongeka. Masero eNK anourayawo masero ane bundu nenzira yakafanana, zvikurukuru kana masero ane bundu ane mamorekuru mashoma eMHC kirasi I pamusoro pawo kupfuura zvakajairika; ichi chinhu chinowanzoitika nemamota. Dzimwe nguva masoja anorwisa masero emudumbu anogadzirwa achibvumira kuti aparadzwe nesystem yecomplement. Zviri pachena kuti mamwe mamota anopukunyuka immune system oenderera mberi achiva kenza. Masero emamota anowanzova nenhamba yakaderera yemamolekyu eMHC kirasi I ari pamusoro pawo, nokudaro achidzivisa kuonekwa nemasero eT anouraya. Mamwe masero emamota anobudisawo zvinhu zvinodzivisa masoja okuzvidzivirira; somuenzaniso kupfurikidza nokuparadzira cytokine TGF- β, iyo inodzvinyirira basa remacrophage nema lymphocyte. Mukuwedzera, kutsungirira kwokurwisa utachiona kungatanga kurwisa maantigen ehutachiona, saka gadziriro yokudzivirira zvirwere haichagoni...  Mubvunzo: Zvirwere zvinoratidzei?
maantigen