Nyorai mberi kweiyi ndima - Heche akaonekwa mumutambo mudiki-diki "Hupenyu hwepabonde" (2005), achirondedzera hupenyu hwemazuva ano hwerudo uye achitamba pamwe naAzura Skye naElizabeth Banks. Firimu racho rakaratidzwa mumutambo wemufirimu uye rakagamuchira kuratidzwa kweterevhizheni. Muna 2006 Heche akatanga kushanda pachake akatevedzana, "Varume vari Miti". Muchiratidziro, akabata semunyori weNew York, uyo mushure mekuziva kuti mukomana wake ari kumubiridzira, anotamira kuguta diki muAlaska, iro rinoitika kuve rakawanda nevarume vasina kuroora uye vakadzi vashoma. "Varume vari Mumiti" vakadzimwa muna May 2008, pashure penguva yakapfupikiswa nokurova kwavanyori
. Munguva yekuratidzwa kwechiratidziro, Heche akabata nyeredzi mune inotyisa-komedhi "Kutambura Kwemunhu Charity" (2007), iyo yerudo komedhi "Chii Rudo" (2007), uye sainzi-fungidziro inonakidza "Toxic Skies" (2008), ese ayo akaenda zvishoma-akaonekwa nevateereri.