On 9 Kurume 2009 De Canio akasaina chibvumirano kuva murairidzi mukuru Serie A relegation varwi Lecce, achitsiva Mario Beretta panguva chidhiraivho "salentini", asi haana kukwanisa kuponesa divi kubva relegation. Musi wa31 Chivabvu 2009 US Lecce yakazivisa kuti De Canio akaramba kuwedzera kondirakiti yake nekirabhu; zvisinei, musi wa6 Chikumi kirabhu yakasimbisa zviri pamutemo kuti vasvika pachibvumirano neyaimbova maneja weQPR, uyo akatungamira "giallorossi" kudzokera kunhandare yepamusoro, semutambi wenhabvu, mumushandirapamwe wavo wa2009-10 Serie B. Akadzingwa musi wa22 Chivabvu 2011 sezvo Lecce akapedza 17th pakupera kwemwaka wa2010-11
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