Mamwe maProhibitionists nevamwe vatsigiri vaBryan vakaedza kugombedzera mukwikwidzi wenguva nhatu wemutungamiri wenyika kuti apinde musarudzo yemutungamiri wenyika ya1920 uye sarudzo ye "Literary Digest" yakatorwa pakati pa1920 yakaratidza Bryan semunhu wechina anozivikanwa zvikuru mumiriri weDemocratic. Bryan, zvisinei, akaramba kutsvaka nzvimbo yehurumende, achinyora kuti "kana ndikakwanisa kubatsira nyika ino kubvisa doro uye pashure pacho kubvisa hondo... hapana nzvimbo, hapana Hutungamiri, inogona kupa kukudzwa kunenge kuri kwangu". Akapinda Democratic National Convention ya1920
senhume yaibva kuNebraska, asi akaodzwa mwoyo nokusarudzwa kwaGavhuna James M. Cox, uyo akanga asina kutsigira kubvumidzwa kweGumi neChisere Amendment. Bryan akaramba kusarudzwa kwemutungamiri wenyika neProhibition Party uye akaramba kurwira Cox, achiita kuti mushandirapamwe wa1920 uve wekutanga mumakwikwi emutungamiri wenyika mumakore anopfuura makumi matatu umo iye asina kushingaira mushandirapamwe.