Horace Wells akaita kuratidzwa kwekutanga kwevanhu vose kweanesthetic inhaling paMassachusetts General Hospital muBoston muna 1845. Zvisinei, nitrous oxide yakapiwa zvisina kukodzera uye murwere akachema mukurwadziwa. Musi wa16 Gumiguru 1846, chiremba wemazino weBoston William Thomas Green Morton akapa kuratidzwa kwakabudirira achishandisa diethyl ether kuvadzidzi vezvokurapa panzvimbo imwechete. Morton, uyo akanga asingazivi nezvebasa raLong rakapfuura, akakokwa kuMassachusetts General Hospital kuti aratidze nzira yake itsva yekuvhiya pasina kurwadziwa. Mushure mekunge Morton aita anesthesia, chiremba John Collins Warren akabvisa bundu kubva pamutsipa waEdward Gilbert Abbott. Izvi zvakaitika mune yekuvhiya amphitheater yava kunzi Ether Dome muna 1831.
Varume, uku hakusi kunyengera