Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Passage: Kazhinji, metabolism inodzidzwa nenzira yekudzikisa inotarisa pane imwe nzira yemetabolism. Kunokosha zvikuru kushandiswa kwezvinhu zvinoratidzira zvine mwaranzi mumuviri wose, mumatehwe uye mumasero, izvo zvinotsanangura nzira dzinobva pazvinhu zvinotangira kusvika kuzvinhu zvokupedzisira nokuziva zvinhu zviri pakati nepakati uye zvinhu zvine mwaranzi zvine mwaranzi. Maenzayimu anokonzera kuti makemikari aya aite anogona kucheneswa uye kinetics yawo nemhinduro dzayo kuzvinodzivisa dzinogona kuongororwa. Nzira yakafanana ndeyokuziva mamorekuru maduku ari musero kana kuti munyama; boka rakazara remamorekuru aya rinonzi metabolome. Zvose mune zvose, zvidzidzo izvi zvinopa maonero akanaka echimiro uye kushanda kwenzira dzinoshandiswa mumuviri, asi hazvina kukwana kana zvichishandiswa kuzvirongwa zvakaoma zvakadai semetabolism yesero rakazara. Pfungwa yezvakaoma kunzwisisa zvemagetsi emagetsi mumasero ane zviuru zvema enzymes akasiyana-siyana inopiwa nomufananidzo unoratidza kudyidzana pakati pemapuroteni 43 chete uye 40 metabolites kurudyi: kutevedzana kwegenomes kunopa mazita ane chero chinhu chinosvika 45,000 genes. Zvisinei, zvino zvinobvira kushandisa iyi genomic data kuvakazve nzanga yakakwana yemhinduro dzebiochemical ndokugadzira mienzaniso yakawanda yemasvomhu yakakwana iyo inogona kutsanangura nokufanotaura mufambiro wavo. Mienzaniso iyi ine simba zvikuru apo inoshandiswa kubatanidza nzira uye metabolite data yakawanikwa nenzira dzekare nemashoko pamusoro pekutaura kwemajini kubva kuproteomic uye DNA microarray zvidzidzo. Uchishandisa unyanzvi uhwu, muenzaniso womutambo womuviri womunhu wava kugadzirwa zvino, uyo uchatungamirira kuwanwa kwemishonga kwomunguva yemberi nokutsvakurudza kwemakemikoro. Mienzaniso iyi yava kushandiswa pakuongorora masangano, kuti zvirwere zvevanhu zvibatanidzwe mumapoka ane mapuroteni akafanana kana kuti zvinoshandiswa pakuita zvimwe zvinhu. Masangano emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo emashandisirwo.  Mubvunzo: Pashure pokuchenesa, chii chiripo chokutarisirazve kubva muiyi purojekiti?
Kinetics yavo nemhinduro ku inhibitors yakaongororwa