Castro akaita mutambo wake wokutanga wenyika yose nokuda kwechikwata chenyika yebhora reMexico muLos Angeles mumutambo wehushamwari neArgentina musi waFebruary 4, 2003. Ricardo La Volpe akamutamba saRight Winger senguva dzose, asi semunhu wepakati panzvimbo pemudziviriri. Akatamba mutambo wake wokutanga weWorld Cup nePortugal muGermany, mutambo uyo vaMexico vakarasikirwa 2-1. Pasinei nokuti chikwata chacho chakarasikirwa nemutambo wacho, Castro akabatsira nyika yake kusvika kuRound of 16 uko vakatamba neArgentina. Kubvira ipapo, ave achishevedzwa kuti atambe mitambo yeushamwari. Akatodanwa kuti atambe mumitambo yeGold Cup ya2007
uye Copa América yeMexico. Munguva pfupi yapfuura, akashevedzwa nemurairidzi weMexico Javier Aguirre kuGold Cup ya2009. Akahwina chibodzwa chake chega chenyika dzese kurwisa United States mu2009 CONCACAF Goridhe Mukombe Final.