Kubva TRIPS yakatanga kushanda, yave ichitsoropodzwa nenyika dzichiri kusimukira, vadzidzi, uye masangano asiri ehurumende. Kunyange zvazvo kumwe kwekutsoropodza uku kuri kupokana neWTO, vazhinji vanotsigira kusunungurwa kwekutengeserana vanoonawo TRIPS sehurongwa husina kunaka. Mhedzisiro yeTRIPS yekudyidzana kwehupfumi (kufambisa mari kubva kuvanhu vari munyika dzichiri kusimukira kuenda kune vane kodzero uye varidzi vepatent munyika dzakasimukira) uye kumanikidza kwayo kushomeka kwekugadzirwa kune vagari venyika dzaizove nedzimwe nzira dzaive nemitemo isina kusimba yezvivakwa, ndizvo zvakajairika hwaro hwekushoropodza kwakadai. Kumwe kushoropodza kwakanangana nekutadza kweTRIPS kukurumidza kudyara uye tekinoroji kuyerera kune nyika dzine mari shoma, rubatsiro rwunotungamirwa nenhengo dzeWTO mukuumbwa kwechibvumirano. Zvirevo zveWorld Bank kuti TRIPS haina kutungamira mukuratidzwa kwekumhanyisa kwekudyara kune nyika dzine mari shoma, kunyangwe vamwe vatsigiri vek
nyika dzichiri kusimukira