Acetanilide ndiye akatanga aniline rinobva serendipitously kuwanikwa kuva analgesic uyewo antipyretic ehupfumi, uye nokukurumidza akasuma kupinda dzokurapa tsika pasi zita Antifebrin kubudikidza Cahn & Hepp muna 1886. Asi ayo zvisingagamuchirwi chepfu migumisiro <unk> zvikuru kunotyisa ari cyanosis nokuda methemoglobinemia <unk> akakurudzira kutsvaka zvishoma chepfu aniline rinobva. North Harmon Morropse akanga atoita synthesized paracetamol pana Johns Hopkins University Via kuderedza p-nitrophenol pamwe tini mu glacial acetic asidhi muna 1877, asi hazvina kusvikira 1887 kuti kurapwa pharmacologist Joseph von Mering vakaedza paracetamol pamusoro vanhu. Muna 1893, Leon von Mering yakabudisa pepa achitaura pamusoro zvokurapa kunoguma paracetamol pamwe phenacetin, imwe analgesic rinobva phenacetin.
Gore ra1963