Ramba uchiverenga ndima ino - Mushure mekufa kwemutauriri uye shamwari yaRyan White muna 1993, Jackson akashandisa mukurumbira wake kuunza kutarisisa kwepasi rose kudenda reAIDS, kunyanya kuburikidza neushamwari hwake naRyan uye nekuita kwake nerudo naElizabeth Taylor. Michael akakumbirawo hurumende yaClinton pamutambo waBill Clinton wokugadzwa
kupa mari yakawanda kumasangano anobatsira HIV/AIDS nokutsvakurudza, uye vakaita "Gone Too Soon", rwiyo rwakazvitsaurira kuna White, uye "Heal the World" pamutambo wacho. Muna January 1994, Jackson "akazarura Neverland Ranch yake mukupemberera Zuva Rokuzvarwa raMartin Luther King nokuda kwavana 100 vomuguta vaiva vakatanhamara muchikoro". Muna 1995, pashure pokunge averenga nhau dzomupepanhau dzorufu rwomukomana aiva nemwedzi 22, Jackson akanzwa achida kupa mari isingazivikanwi kumari yemhuri yakatangwa neSt. Mary Medical Center muLong Beach, California. Aimbotsigira kodzero dzengochani, munaFebruary 1997, Jackson akapa bhachi reHIStory Tour uye bhuku rezviyeuchidzo rakasainwa kuti riwane mari yekutsigira mutambo wekutanga weHawaii weGay uye Lesbian Cultural Festival.