Rangarira ndima iri pasi apa uye ipapo pindura mubvunzo gare gare mumutauro mumwe chetewo sechikamu:  Kupfuura: GH inokurudzirawo, kupfurikidza nenzira yeJAK- STAT yokuratidzira, kugadzirwa kwe insulin- yakafanana nechinhu chokukura 1 (IGF-1, kare yaizivikanwa se somatomedin C), hormone yakafanana neproinsulin. Chiropa ndicho nhengo inonyanya kushandiswa neGH pakuita izvi uye ndiyo nzvimbo huru inogadzirwa IGF-1. IGF-1 ine migumisiro inokurudzira kukura pamhando dzakasiyana-siyana dzezvinyama. IGF-1 inowedzerwa inogadzirwa mukati mematehwe anotarirwa, ichiita kuti ive inoratidzika kunge iri endocrine uye autocrine / paracrine hormone. IGF-1 inewo migumisiro inokurudzira pane osteoblast uye chondrocyte basa kukurudzira kukura kwemapfupa. Kuwedzera pakuwedzera kukwirira muvana nevechiri kuyaruka, kukura kwehomoni kune zvimwe zvakawanda zvinokonzera muviri:  Mubvunzo: Chii chine mhedziso yokufananidzira?
IGF-1