The Peruvian Confederation yakapikiswa nenyika dzakavakidzana kubva pakuvambwa kwayo, kunyanya Chile neArgentina, sekutyisidzira kwehondo uye kwehupfumi, uye nerutsigiro rwayo kune vanopikisa vari muutapwa. Hondo yeConfederation
kwakatangwa nokukurumidza pashure pokuumbwa kwaro apo Chile neArgentina vakazvimiririra vakapinda munyika yacho. Argentina yakakundwa muna 1837, asi simba rakabatanidzwa reChile neNorth Peruvian vapanduki vaizivikanwa seUnited Restoration Army vakakunda muhondo yeYungay muna Ndira 1839, iyo "de facto" yakapedza mubatanidzwa sezvo Peru neBolivia zvakadzorerwa senyika dzakazvimirira, uye Santa Cruz akatizira kunze kwenyika. Peru-Bolivian Confederation yakaziviswa zviri pamutemo kuti yaparara musi waAugust 25, 1839, naGeneral Agustín Gamarra mushure mekugadzwa kwake semutungamiri wePeru.