Zvimwe zvinodhaka zvinoderedza kushanda kwepiritsi uye zvinogona kukonzera kubuda ropa, kana kuwedzera mukana wekubata pamuviri. Izvi zvinosanganisira zvinodhaka zvakadai se rifampicin, barbiturates, phenytoin uye carbamazepine. Uyezve nyevero dzinopiwa pamusoro pemishonga inorwisa mabhakitiriya yakawanda, yakadai se ampicillin uye doxycycline, iyo inogona kukonzera matambudziko "nekukanganisa mabhakitiriya anokonzera kudzokorora ethinylestradiol kubva mumatumbo makuru" (BNF 2003).
Mimwe mishonga