Pedzisa mutsara unotevera: Pasinei nokurwara kwaaiita, Wilson aida kuti azotonga kechitatu. Nepo
1920 Democratic National Convention yakatsigira zvakasimba mitemo yaWilson, vatungamiri veDemocratic vakaramba, vachidoma panzvimbo yetikiti raiumbwa naGavhuna James M. Cox uye Mutevedzeri Wemunyori weNavy Franklin D. Roosevelt. VaRepublican vakaisa mushandirapamwe wavo pakushora mitemo yaWilson, naSenator Warren G. Harding vachivimbisa "kudzokera kumamiriro ezvinhu akajairika". Wilson haana kubatanidzwa zvikuru mumushandirapamwe wacho, kunyange zvazvo akatsigira Cox uye akaramba achitsigira kuti United States ive nhengo yeLeague of Nations. Harding akahwina nechisimba, achikunda zvinopfuura 60% zvemavhoti akakurumbira uye nyika dzose dziri kunze kweSouth. Wilson akasangana naHarding kuti vanwe tii pazuva rake rokupedzisira ari muhofisi, March 3, 1921. Nemhaka yeutano hwake, Wilson akanga asingakwanisi kupinda muchitsauko chokutanga.