Ma nucleases anoshandisa hydrolyse nucleotides kubva kumagumo eDNA tambo anonzi exonucleases, nepo endonucleases achicheka mukati mematanho. Ma nucleases anonyanya kushandiswa mu molecular biology ndiwo marambidzo endonucleases, ayo anocheka DNA pane zvakateedzana. Semuenzaniso, iyo EcoRV enzyme inoratidzwa kuruboshwe inoziva iyo 6-base nhevedzano 5′-GATC-3′ uye inoita kucheka pamutsetse wakatwasuka. Muchisikirwo, aya ma enzyme anodzivirira mabhakitiriya kubva kuhutachiona hwephage nekudyara iyo phage yekugadzirisa DNA painopinda muchitokisi chebhakitiriya, sechikamu chehurongwa hwekurambidza. Mune tekinoroji nhevedzano, aya ma nucleases anoshandiswa mumamolekuru kutevedzera uye kutevedzera DNA. Mubvunzo: Chii chinozivikanwa neEcoRV enzyme?
6-base sequence 5′-GATATC-3