Nyorera kupfuurira kweiyi ndima - Munguva yesarudzo yemutungamiri wenyika ya2004, DiCaprio akaita mushandirapamwe uye akapa mari kuJohn Kerry's presidential bid. Akapa madhora 2.300 kukambani yaBarack Obama yokutsvaka kutungamirirwa nehurumende
musarudzo dza2008, mari yakawanda yaigona kupiwa nemunhu musarudzo idzodzo, uye $5,000 kumushandirapamwe waObama wa2012. DiCaprio akatsigira Hillary Clinton musarudzo dzemutungamiri wenyika dza2016. Muna Kurume 2020, DiCaprio akapinda musangano wekuunganidza mari yaJoe Biden kumba kwemukuru weParamount Pictures Sherry Lansing.