O le vailaʻau muamua mo le toto maualuga, sodium thiocyanate, na faʻaaogaina i le 1900 ae na tele aʻafiaga ma e leʻi lauiloa. E tele isi vailaʻau na atiaʻe ina ua maeʻa le Taua Lona Lua a le Lalolagi, o le sili ona lauiloa ma talafeagai lelei o tetramethylammonium hexamide, chlorethonium, hydralazine, ma le renal sulfate (maua mai le laau o le Serpentine). E leai se tasi o nei na faʻaaogaina.
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