Faatupuina se lomiga e sili atu ona lavelave o lenei fuaiupu Claisen toe faatulagaina'' faagasolo e ala i le faamafanafanaina o allylic ava malosi i le afioaga o'' N, N -'' dimethylacetamide dimethyl acetal e fausia ai γ, δ - unsaturated amide.
O le mea moni, o se lomiga e sili atu ona lavelave o le fuaiupu o le "Claisen toe faatulagaina '' faagasolo mai se allylic ava malosi i se γ, δ - unsaturated amide, ma na atiina ae e Albert Eschenmoser i le 1964. "