I le ogatotonu o le 1970s, Harvey J. Alter, Ofisa Sili o le Vaega o Faamaʻi pipisi i le Matagaluega o Faʻasologa o Faʻasologa i le National Institutes of Health, ma lana 'au suʻesuʻe na faʻaalia ai le tele o faʻamaʻi pipisi o le hepatitis e leʻi mafua mai i le hepatitis A poʻo le B. E ui lava i lenei mea na maua, o taumafaiga suʻesuʻe faʻavaomalo e faʻailoa ai le siama, na muamua taʻua o le non-A, non-B hepatitis (NANBH), na le manuia mo le isi sefulu tausaga na sosoo ai. I le 1987, Michael Houghton, Qui-Lim Choo, ma George Kuo i le Chiron Corporation, galulue faʻatasi ma Daniel W. Bradley i le Centers for Disease Control and Prevention, na faʻaaogaina se auala fou o le faʻasologa o le faʻasologa e faʻailoa ai le meaola e le iloa ma faʻataʻitaʻi ai se suʻega. I le 1970 na faʻamaonia e
Tausaga 1987