O le tupulaga o kulukose mai tuufaatasi e pei o pyruvate, lactate, glycerol, glycerate 3-phosphate ma amino acids ua taʻua o gluconeogenesis. Gluconeogenesis liua pyruvate i glucose-6-phosphate e ala i se faasologa o intermediates, o le tele o lea ua faasoaina ma glycolysis. Ae peitai, e le na o lenei ala o glycolysis tamoʻe i tua, e pei o le tele o laasaga ua catalyzed e non-glycolytic enzymes. O lenei auala e taua e pei ona faatagaina ai le faavaeina ma le faavaivaia o le kulukose e tatau ona faatonutonuina ma e le mafai ona taofia uma auala mai tamoʻe i se faataamilosaga polysaccharide. O se auala e gaosia ai le kulukose mai gaʻo pei o pyrroxyl, glycosyl, glycosyl, glycosyl, glycosyl, glycosyl poʻo le acetyl acetate. O le mea e mafai ona faia e ala i le tuuina atu o nei meaola
e manaʻomia e manu feʻai ona maua ni tino ketone mai i gaʻo e sui ai le kulukose i totonu o aano e pei o le faiʻai e lē mafai ona faʻaaogaina ai gaʻo