O le DNA o se seti o tolu-nucleotide seti ua taʻua o codons ma taʻitasi tolu-nucleotide tuʻufaʻatasia faʻailogaina se amino acid, mo se faʻataʻitaʻiga o le AUG (adenine-uracil-guanine) o le code mo methionine. Talu ai o le DNA o loʻo i ai le fa nucleotides, o le aofaʻi o numera o codons mafai ona 64; o lea, o loʻo i ai sina faʻasologa i le genetic code, ma nisi amino acids faʻamaoti mai e le sili atu ma le tasi codon. Genes faʻailogaina i le DNA ua muamua faʻaliliuina i le biosynthetic pre-mRNA (mRNA) e ala i faʻamatalaga o loʻo faʻailogaina i genes.
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