O nei cofactors auauna atu i le tele o faamoemoega; mo se faataitaiga, uʻamea ions e mafai ona fesoasoani i le faamautuina o nucleophilic ituaiga i totonu o le nofoaga toaaga. cofactors faatulagaina e mafai ona coenzymes, lea ua faamaloloina mai le nofoaga toaaga o le enzyme i le taimi o le tali, po o vaega prosthetic, lea ua fusifusia lelei i se enzyme. vaega prosthetic faatulagaina e mafai ona covalently (eg, i enzymes biotin e pei carboxylase). O se faataitaiga o se enzyme o loo i ai se cofactor covinic, lea o loo i ai le tele o carbon hydrolysis, lea o loo faaalia i le ata i luga o se vaega o le enzyme toaaga. O nei cofactors e masani lava ona manaomia se coenzyme o loo i ai se vaega atoatoa o carbon anehydrase poʻo se mea e mafai ona fusifusia lelei faatasi ma le vaega o le enzyme.
tuufaatasiga faatulagaina