Faʻamatalaga: O le fesoʻotaʻiga faʻagaoioia auala amata i le faʻavaeina o le muamua faʻafitauli i luga o collagen e maualuga-mole mamafa kininogen (HMWK), prekallikrein, ma FXII (Hageman vaega). Prekallikrein ua liua i kallikrein ma FXII avea FXIIa. FXIIa liua FXI i FXIa. Factor XIa faʻagaoioia FIX, lea ma lona co-factor FVIIIa fausia ai le tenase complex, lea e faʻagaoioia i FXXa. O le laʻititi matafaioi o le fesoʻotaʻiga faʻagaoioia auala i le amataina o clot fausiaina mafai ona faʻaalia e le mea moni o tagata mamaʻi ma ogaoga faʻaletonu o FXII, HMWK, ma prekallikrein e leai se toto faʻaletonu. Nai lo lena, fesoʻotaʻiga faiga foliga mai e sili atu ona aʻafia i le fulafula, ma le puipuiga faʻaleagaina. E ui lava i le faʻalavelave i lenei
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