N'April 21, 1992, Guillén merụrụ nnukwu ahụ́ n'ikpere mgbe ya na onye na-agbapụ bọl n'èzí bụ́ Tim Raines kụkasịrị. Mmerụ ahụ mere ka ọ hapụ ihe fọrọ nke nta ka ọ bụrụ oge niile, ma mechaa belata ebe nchekwa ya yana mmepụta ya zuru ezu maka ọrụ ya fọdụrụnụ. Guillén gbakere na 1993 na oge ya kachasị arụpụta ihe na-awakpo, na-eziga.280 batting nkezi, na ọrụ dị elu na 4 home runs na 50 agbapụ agbapụ, dị ka White Sox meriri aha American League Western Division. Ọ gbara.273 ma gbaa ọsọ 4 n'ime mgbalị na-efunahụ, dịka ndị White Sox meriri ndị Toronto Blue Jays na 1993 American League Championship Series
Ọ dị mma.