Mezue ahịrịokwu na-esonụ: Williams malitere oge 2015 site na-anọchite anya United States n'akụkụ John Isner na
Iko Hopman. Ndị Amerịka abụọ ahụ meriri ndị Poland n'asọmpi ikpeazụ. Na Australian Open, Williams meriri Maria Sharapova maka oge nke iri na isii na-aga n'ihu iji nweta aha nke isii nke Australian Open na aha nke iri na itoolu nke Grand Slam, na-emeri aha ya na egwuregwu nke atọ ya na nke abụọ. Site na mmeri a, Williams karịrị ma Evert na Navratilova, maka nke abụọ kachasị Grand Slam aha ndị mmeri meriri na Oge Open. Aha ahụ bụkwa aha Grand Slam nke isii ya kemgbe ọ gbara afọ 30, atọ karịa nke na-esote ya (Margaret Court, Martina Navratilova nwere atọ ọ bụla). Ọ bụ naanị onye ọkpụkpọ n'akụkọ ihe mere eme meriri Grand Slam anọ niile ma ọ dịkarịa ala otu mgbe ọ gachara afọ iri atọ. Na ngwụcha izu na-esote, Serena na nwanne ya nwanyị Venus gara Buenos Aires ịlụso Argentina ọgụ na World Group II tie maka Fed Cup. Ọ gbara ma merie naanị egwuregwu ya megide María Irigoyen iji nyere Team USA aka imeri Argentina 4-1. Williams kwupụtara na ọ ga-asọ mpi na Indian Wells Masters na-akwụsị afọ iri na anọ ọ na-eme ngagharị iwe nke ihe omume ahụ. Mgbe ọ laghachiri, ndị Williams guzoro n'ihu igwe mmadụ wee merie egwuregwu mbụ ya na setịpụrụ. Ọ ruru ọkara-ikpeazụ, ebe ọ ga-eche ihu Nke 3, Simona Halep, maka ebe na njedebe, mana a manyere ya ịdọrọ n'ihi mmerụ ahụ ikpere. Site na mmeri Sabine Lisicki na quarterfinals nke Miami Open, Williams ghọrọ naanị nwanyị nke asatọ na Open Era iji dekọọ mmeri egwuregwu 700 na ọrụ ya. Nke a mekwara ka ọ bụrụ otu n'ime naanị ndị egwuregwu atọ na-arụ ọrụ iji merie egwuregwu 700 ma ọ bụ karịa n'otu egwuregwu, ndị ọzọ bụ Roger Federer na Rafael Nadal. Na ọkara ikpeazu o meriri Halep iji gafee na nke ikpeazụ ya nke iri na ihe omume ahụ ebe o meriri aha nke asatọ ma gbasaa mmeri ya ruo 21 site na imeri Carla Suárez Navarro.