Mezue ahịrịokwu na-esonụ: N'afọ 1991, Barghouti bụ onye nnọchiteanya na
Nzukọ Madrid, nke e mere na ebumnuche nke ịkwụsị esemokwu Israel-Palestine na Intifada nke Mbụ. N'afọ 1996, ọ gbara ọsọ na-enweghị ihe ịga nke ọma dị ka onye na-aga ime ụlọ omebe iwu na ntuli aka mbụ nke Palestine. N'afọ 2002, Barghouti hapụrụ ndị Palestinian People's Party. Na June 2002, Barghouti, Haidar Abdel-Shafi, Ibrahim Dakkak na Edward Said guzobere Palestinian National Initiative ("al-Mubadara al-Wataniyya al-Filistiniyya"), mgbalị iji wuo mgbanwe, nke na-agụnye ndị ọzọ na ndị guzobere Palestine Liberation Organization na ndị otu ndị agha Islam dị ka Hamas. Barghouti na-eje ozi ugbu a dị ka odeakwụkwọ ukwu nke Initiative.