Mezue ahịrịokwu na-esonụ: Na November 1576, ndị Spen
Ha kwakọọrọ ma gbaa Antwerp ọkụ - nke mere ka ọ gharazie ịbụ ebe azụmahịa na obodo kasị baa ọgaranya na Europe - Plantin kwụrụ nnukwu ego mgbapụta iji chebe ebe obibi akwụkwọ ya. O hiwere alaka ụlọ ọrụ ya na Paris. N'afọ 1583, ndị ọchịchị Netherlands chọrọ onye ga-arụ ọrụ na mahadum Leiden e wuru ọhụrụ. Plantin kwagara ebe ahụ mgbe o nyefechara ndị ọgọ ya nwoke bụ́ John Moerentorf na Frans van Ravelingen (Raphelengius) obere ọrụ ya dị n'Antwerp. Plantin hapụrụ ọfịs ya dị na Leiden nye Raphelengius ma laghachi Antwerp mgbe ọ ghọsịrị ebe a na-edozi ahụ, na-esote mmeri ya site n'aka onye isi Parma na 1585. Plantin rụsiri ọrụ ike n'Antwerp ruo mgbe ọ nwụrụ.