Dee ihe na-esote paragraf a - Cleopatra gara Rom dịka eze nwanyị onye ahịa na 46 na 44 BC, na-anọ na villa ya. Mgbe e gbusịrị Siza na 44 BC, Cleopatra nwara ime ka a họpụta Siza dị ka onye ga-anọchi ya. Octavian, bụ́ nwa nwanne Caesar (onye a maara dị ka Augustus na 27 BC, mgbe ọ ghọrọ eze ukwu Rom mbụ) gbochiri nke a. Cleopatra meziri ka e gbuo nwanne ya nwoke bụ́ Ptolemy nke Iri na Anọ ma mee ka nwa ya nwoke bụ́ Caesarion soro ya chịa. N'agha obodo nke ndị nnwere onwe
N'agbata afọ 43 na 42 BC, Cleopatra sonyeere ndị Roman Triumvirate nke abụọ nke Octavian, Mark Antony, na Marcus Aemilius Lepidus. Ya na Mark Antony nwere mmekọrịta nke ga-emecha mụta ụmụ atọ: ejima Alexander Helios na Cleopatra Selene nke Abụọ, na Ptolemy Philadelphus. Antony ji ikike ya dị ka onye na-achị achị mee ihe iji gbuo Arsinoe nke Anọ n'arịrịọ Cleopatra. Ọ malitere ịdabere na Cleopatra maka ma ego ma enyemaka ndị agha n'oge mwakpo ya nke Alaeze Ukwu Parthian na Alaeze Armenia. Ọ bụ ezie na mwakpo ọ wakporo Parthia kụrụ afọ n'ala, o jisiri ike weghara Armenia. Ọ kpọghachitere Eze Artavasdes nke Abụọ na Alexandria na 34 BC dị ka onye mkpọrọ na mmeri ya nke ndị Rom nke Cleopatra kwadoro. Nke a sochiri onyinye nke Alexandria, nke ụmụ Cleopatra na Antony nwetara ókèala dị iche iche n'okpuru ikike nke Antony. A kpọrọ Cleopatra Eze Nwanyị nke Ndị Eze, kpọọkwa Caesarion Eze nke Ndị Eze. Ihe omume a, tinyere alụmdi na nwunye Antony na Cleopatra na ịgba alụkwaghịm nke Octavia Minor, nwanne nwanyị Octavian, bụ akara mgbanwe nke dugara na Agha Ikpeazụ nke Republic Rom.