Mezue ahịrịokwu na-esonụ: Na 1776, Tyszkiewicz bụ onye nnọchi anya Sejm site na Vilnius Voivodeship. na 1778 e mere Marshal nke Sejm. Na 1782, ọ bụ onye na-akwado Council Council. N'oge
Polish-Russian War nke 1792, na nzukọ nke July 23, ọ kwadoro ịbanye eze na Targowica Confederation, onye ihe atụ Tyszkiewicz n'onwe ya mechara soro, wee bụrụ Grand Marshal nke Lithuania. N'oge Grodno Sejm, a họpụtara ya ka ọ bụrụ onye na-ekwu okwu na onye nnọchi anya Russia bụ Jacob Sievers, yabụ na 22 Julaị 1793 ọ bịanyere aka na nkwekọrịta nke inyefe Russia ala, na mgbe ahụ na 25 Septemba na Prussia, dịka akụkụ nke nkewa nke abụọ nke Poland. N'afọ 1795, ọ bụ onye ndu nke ndị Lithuanian na-asọpụrụ Catherine nke Abụọ.