Dee ihe na-aga n'ihu na paragraf a - Nwa akwukwo iwu, o bidoro ọrụ agha ya mgbe ọ dị afọ iri na asatọ, na-esote nguzobe nke juntas na 1810, nke malitere usoro nnwere onwe na New Granada. Santander sonyere ndị agha mgbanwe na Ọktoba 1810, na battalion National Guard ("Guardias Nacionales"). Ọ buru ụzọ jee ozi dị ka onye agha na ndị agha nke United United Provinces nke New Granada, n'okpuru iwu nke General Antonio Baraya, nke lụrụ ọgụ megide General Antonio Nariño, nke Mpaghara Cundinamarca, onye jụrụ ịnakwere ikike nke Union. N'oge mkpọsa ndị a, Santander nwetara ọkwa nke onye ọchịagha na 1812. Mgbe ndị agha ndị eze meriri New Granada
, Santander dị ka ọtụtụ ndị isi ndị ọzọ nke New Granada laghachiri na mbara ọzara nke ọwụwa anyanwụ nke Cordillera Oriental, ndị Llanos, na nso oke ala Venezuela nke oge a. N'ebe ahụ, Santander sonyeere ndị na-ahụ maka ịhụ mba n'anya na Venezuela ma rụọ ọrụ n'okpuru Simón Bolívar. N'oge agha agha gafere Andes, Bolívar buliri Santander n'ọkwá Brigadier General na 1817.