Mezue ahịrịokwu na-esonụ: Guthe kwagara United States n'oge okpomọkụ nke 1892 ịlụ Clara Belle Ware (1867-1947), si Grand Rapids, Michigan. Di na nwunye ahụ zutere n'oge nleta Ware na Germany na 1890-91. N'afọ 1893, ọ ghọrọ onye nkụzi na-akụzi physics na Mahadum Michigan, na 1900 e buliri ya n'ọkwá ịbụ osote prọfesọ. N'afọ 1903, Guthe nwetara ọrụ dịka onye enyemaka onye na-ahụ maka ihe gbasara ahụike na National Bureau of Standards e hiwere ọhụrụ na Washington, D.C. (ugbu a bụ National Institute of Standards and Technology). N'afọ 1905, ọ nabatara ọkpụkpọ òkù ịghọ Prọfesọ nke Physics na Onye isi oche nke Ngalaba Physics na Mahadum Iowa. Guthe bụ onye otu ndị juri nke ihe nrite na
St. Louis Exposition na 1904 ma bụrụ osote onye isi oche nke American Association maka Ọganihu nke Sayensị na 1908. N'afọ 1909, Mahadum nke Michigan gwara Guthe ka ọ lọta dịka Prọfesọ zuru oke na Ngalaba Physics, ọ laghachikwara Ann Arbor na ezinụlọ ya na-eto eto. N'afọ 1912, a họpụtara Guthe Dean nke ụlọ akwụkwọ gụsịrị akwụkwọ ọhụrụ na Mahadum Michigan.