Mezue ahịrịokwu na-esonụ: Mgbe oge abụọ na-aga nke ọma na-enweghị ọdịdị egwuregwu, ndị Astros bụ ndị mbụ na-ahọrọ iji merie 2004 NL pennant. Ha tinyere kpakpando pitcher Andy Pettitte na roster nke ugbua gụnyere standouts dị ka Lance Berkman na Jeff Kent nakwa dị ka ndị agha ochie Bagwell na Biggio. Roger Clemens, onye lara ezumike nká mgbe oge ya na New York Yankees gachara, kwetara isonyere onye otu ya bụ Pettitte na Astros maka 2004. Nkwekọrịta afọ ahụ gụnyere ọnọdụ pụrụ iche, dịka nhọrọ maka Clemens ịnọ n'ụlọ na Houston na njem ụzọ ahọpụtara mgbe ọ na-emeghị ndokwa ịkụ. N'agbanyeghi amụma ndị mbụ maka ihe ịga nke ọma, ndị Astros nwere ihe ndekọ 44 na 44 na ezumike All-Star. Enweghị mmepụta ọsọ na ndekọ dị njọ na egwuregwu dị nso bụ isi okwu. Mgbe a kwụsịrị ya na 2004 All-Star Game nke e mere na Houston, a chụrụ onye nchịkwa Jimy Williams ma dochie ya na Phil Garner, kpakpando na ngalaba mmeri 1986 Astros. Ndị Astros nwere ndekọ 46-26 na ọkara nke abụọ nke oge n'okpuru Garner wee nweta oghere NL. Ndị Astros meriri ndị Braves 3 na 2 na Division Series, mana ha ga-atụfu
National League Championship Series na St. Louis Cardinals n'egwuregwu asaa. Clemens nwetara ihe ndekọ nke asaa Cy Young Award na 2004. Na mgbakwunye, mgbakwunye nke etiti oge nke Carlos Beltrán na azụmaahịa ya na Kansas City Royals nyeere ndị Astros aka nke ukwuu na egwuregwu egwuregwu ha. N'agbanyeghi asịrị nke mgbanwe etiti oge, Beltrán ga-egosi na ọ ga-enyere ndị otu ahụ aka, na-akụ ụlọ asatọ na postseason. Ọ bụ ezie na o kwenyesiri ike na ya chọrọ ịnọgide na Astros, Beltrán bịanyere aka na nkwekọrịta ogologo oge na New York Mets na Jenụwarị 9, 2005.