Mepụta nsụgharị dị mgbagwoju anya nke ahịrịokwu a Claisen rearrangement'' na-aga n'ihu site na ikpo ọkụ allylic alcohols na ọnụnọ nke'' N, N -'' dimethylacetamide dimethyl acetal iji mepụta γ, δ - unsaturated amide.
N'ezie, ụdị okwu dị mgbagwoju anya nke ahịrịokwu ahụ bụ "Claisen rearrangement '' na-esi na allylic alcohol gaa γ, δ - unsaturated amide, Albert Eschenmoser mepụtara ya na 1964. "