Dee ihe ọzọ maka paragraf a - The Ninety-five Theses, nke Martin Luther bipụtara n'afọ 1517, kpalitere Ndozigharị ahụ n'ala ndị Germany, ọtụtụ ndị isi ghọkwara ndị Protestant. Mgbe e bibisịrị Nnukwu Ọgba Aghara nke Ndị Ọrụ Ugbo, a kpọkọtara Nzukọ Ndị Isi nke 1530 iji mee ka esemokwu na-arị elu banyere Protestantism, karịsịa n'ihi egwu nke ọganihu Ottoman; ndị agha nke Sultan Suleiman nke Mbụ fọrọ nke nta ka ha were ebe obibi Habsburg Vienna
na 1529 na Emperor Charles V chọrọ ka Ndị Kraịst dịrị n'otu megide mwakpo ndị ahụ. Mgbe Nzukọ Ndị Isi nke Worms nke 1521 machibidoro Martin Luther na traktị ya iwu, nsogbu nke mmanye pụtara, dị ka agha Charles megide France na nkwa ndị ọzọ nke alaeze ukwu ya gbochiri ya ilekwasị anya na nsogbu okpukpe German.