Mezue ahịrịokwu na-esonụ: Mgbe Zanardi merụsịrị mmerụ ahụ n'ihe ọghọm ịgba ọsọ ya na 2001, o kpebiri ịlaghachi n'egwuregwu, na-agba ịnyịnya ígwè aka. N'afọ 2007, ọ nwetara ebe nke anọ na New York City Marathon na ngalaba handcycle, mgbe naanị izu anọ nke ọzụzụ. Kemgbe ahụ, ọ na-agba ịnyịnya ígwè n'ụzọ dị mkpa, ma soro asọmpi na Para-Cycling Road World Championships na 2009. O kwuru na ya na-achọ ebe ọ ga-anọ n'òtù egwuregwu Ịtali maka asọmpi ahụ.
2012 Summer Paralympics. N'afọ 2009, o meriri Marathon Venice n'ụdị ndị nwere nkwarụ, na-agba oche nkwagharị ya n'ime otu elekere, nkeji iri na atọ, sekọnd 56, ma merie Marathon Rome City na 2010, n'oge otu elekere, nkeji iri na ise, sekọnd 53. N'afọ 2011, na nke anọ ya, Zanardi meriri New York City Marathon na klas ya na-agba ịnyịnya ígwè.