Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Hanyar wucewa: De novo kira na ceramide yana farawa tare da haɗuwa da palmitate da serine don samar da 3-keto-dihydrosphingosine. Wannan aikin yana haifar da enzyme serine palmitoyl transferase kuma shine matakin iyakance saurin hanyar. Hakanan, 3-keto-dihydrosphingosine ya ragu zuwa dihydrosphingosine, wanda aka biyo baya ta hanyar acylation ta enzyme (dihydro) ceramide synthase don samar da dihydroceramide. Sakamakon karshe don samar da ceramide yana ƙaddamar da dihydroceramide desaturase. De novo kira na ceramide yana faruwa a cikin reticulum endoplasmic. Ceramide daga baya ana jigilar shi zuwa na'urar Golgi ta hanyar zirga-zirga ta hanyar zirga-zirga ko kuma kwayar kwayar kwayar CERT. Da zarar a cikin na'urar Golgi, ana iya kara yin amfani da ceramide zuwa wasu sphingolipids, kamar sphingomyelin da glycosphingolipids mai rikitarwa.  Tambaya: Menene ya samar da dihydroceramide
(dihydro) ceramide synthase