Ka cika wannan magana: Antakus bai sake samun mulkinsa ba sai da Sarkin Roma Claudius ya hau gadon sarauta a shekara ta 41. A cikin 43 ɗansa na farko, C. Julius Archelaus Antiochus Epiphanes, ya yi alkawarin aure ga Drusilla, 'yar Agrippa I. Baya ga Epiphanes, Antiochus yana da wasu yara biyu tare da Iotapa: Callinicus da ƙaramin Iotapa. A shekara ta 53, Antiochus ya dakatar da tawayen wasu kabilun barbarous a Cilicia, da ake kira Clitae. A shekara ta 55 ya karbi umarni daga Sarkin sarakuna na Roma Nero don ya tara sojoji don yin
yaƙi da Parthians, kuma a cikin shekara ta 59 ya yi aiki a ƙarƙashin Janar Cn. Domitius Corbulo a kan Sarki Tiridates I na Armenia, ɗan'uwan Sarkin Parthian Vologases I na Parthia. Sakamakon ayyukansa a cikin wannan yaƙin, a cikin shekara ta 61 ya sami sassan Armenia.