Cika wannan jumla: Da yake yana sha'awar siyasar New Deal, ya canza sana'a. An nada Gruening a cikin tawagar Amurka zuwa Taro na 7 na Inter-American a 1933, Daraktan Sashen Yankin Yankin da Kananan tsibirai na Ma'aikatar Cikin Gida, 1934<unk>1939, da kuma Mai Gudanar da Gudanar da Gyara Gyara Puerto Rico, 1935<unk>1937. Ya kasance memba na Alaska International Highway Commission daga 1938 zuwa 1942. A shekara ta 1939, an nada Gruening Gwamnan Yankin Alaska, kuma ya yi aiki a wannan matsayi na shekaru 13 1/2. Ya kasance wakili ne a Babban Taron Kasa na Jam'iyyar Democrat na 1952,
1956, da 1960, kuma an zabe shi zuwa Majalisar Dattijan Amurka a 1958, yana aiki na shekaru 10.