A lokacin, yaduwa na iya faruwa ga kwakwalwa, fata, ko gumis. A matsayin cutar sankara mai tsanani, AML yana ci gaba da sauri kuma yawanci yana mutuwa a cikin makonni ko watanni idan ba a kula da shi ba. Abubuwan haɗari sun haɗa da shan sigari, chemotherapy ko radiation therapy, myelodysplastic syndrome, da kuma haɗari ga sinadarin benzene. Hanyar da ke tattare da maye gurbin ƙwaƙwalwar ƙwayar cuta ta yau da kullun tare da ƙwayoyin jini na yau da kullun, wanda ke haifar da raguwar ƙwayoyin jini a cikin ƙwayoyin jini, platelets, da ƙwayoyin jini na yau da kullun.
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