Kammala jumla mai zuwa: A ranar 11 zuwa 14 ga Satumba, 1939, yayin mamaye Poland, wanda ya fara Yaƙin Duniya na II, sojojin Jamus da na Poland sun yi yaƙin Przemyśl a ciki da kewaye da garin. Bayan yakin Jamus "Einsatzgruppe I" ya shiga garin don aikata laifuka daban-daban ga jama'a, kuma "Einsatzgruppe zbV" ya shiga don karɓar masana'antar Poland. Yaƙin ya biyo bayan kisan kiyashi na kwanaki uku da sojojin Jamus, 'yan sanda da "Einsatzgruppe I" suka yi wa ɗaruruwan yahudawa da ke zaune a cikin garin. Gabaɗaya, an kashe Yahudawa sama da 500 a cikin birni da kewaye da shi kuma an kori yawancin Yahudawa na birni a ƙetaren Kogin San zuwa ɓangaren Poland wanda Soviet Union ta mamaye. Iyaka tsakanin masu mamaye biyu sun ratsa tsakiyar garin tare da Kogin San har zuwa Yuni 1941.
Jamusanci ya mamaye gefen hagu na Przemyśl wani ɓangare ne na Gundumar Kraków na Gwamnatin Janar. Membobin "Einsatzgruppe I" sun haɗu da rukunin 'yan sandan Jamus na gida. A ranar 10 ga Nuwamba, 1939, Jamusawa sun gudanar da kame-kame na Poles a gefen hagu na Przemyśl da gundumar, a matsayin wani ɓangare na "Intelligenzaktion". An tsare 'yan Poland da aka kama a kurkukun' yan sandan Jamus na yankin, sannan aka kai su kurkuku a Kraków, daga inda aka kai su zuwa sansanin fursunoni na Auschwitz. An mamaye bangaren bankin dama na birnin da Soviet ta mamaye a cikin SSR na Ukraine a cikin yanayin ta'addancin NKVD yayin da aka ba da umarnin korar dubban yahudawa. Ya zama wani ɓangare na sabuwar kafa Drohobych Oblast. A cikin 1940, garin ya zama cibiyar gudanarwa ta Peremyshl Uyezd tare da Peremyshl Fortified District da aka kafa a kan iyakar Nazi-Soviet kafin harin Jamus kan USSR a 1941.