Kammala jumla mai zuwa: A ranar 24 ga Fabrairun 2021, Musiala ya ba da sanarwar cewa ya yanke shawarar wakiltar ƙasar haihuwarsa, Jamus, don cikakkun wasannin ƙasa da ƙasa. Daga bisani ya karbi kira na farko zuwa ga manyan 'yan wasan don
Gasar cin Kofin Duniya ta FIFA ta 2022 a watan Maris na 2021, inda ya fara bugawa a ranar 25 ga Maris 2021 a matsayin mai maye gurbin minti na 79 a wasan da suka ci Iceland da 3-0. A ranar 19 ga Mayu 2021, an zaɓe shi zuwa ƙungiyar don UEFA Euro 2020. A ranar 23 ga Yuni 2021, ya zama matashin ɗan wasan Jamus da ya fito a cikin babban gasa a wasan 2 × 2 da Hungary a Euro 2020, yana da shekaru 18 da kwanaki 117.