Kammala jumla mai zuwa: Yaƙin ya fara ne a shekara ta 264 kafin haihuwar Yesu tare da Romawa suna samun kafa a Sicily a Messana (Messina na zamani). Sai Romawa suka matsa wa Syracuse, wadda ita kaɗai ce ƙasa mai iko a tsibirin, ta haɗa kai da su kuma ta kewaye babban sansanin Carthage da ke Akragas. Babban sojojin Carthaginian sun yi ƙoƙarin ɗaga kewaye a cikin 262 BC, amma an ci su da yawa a Yaƙin Akragas. Daga nan sai Romawa suka gina jiragen ruwa don kalubalanci Carthaginians, kuma ta amfani da sababbin hanyoyin da suka yi nasara da yawa. An kama wani sansanin Carthaginian a Corsica, amma an kai hari kan Sardinia; sai aka rasa sansanin a Corsica. Romawa sun yi amfani da nasarar da suka yi a yaƙin teku don su kai wa arewacin Afirka hari, amma mutanen Carthage suka kama su. A yakin Cape Ecnomus an sake doke Carthaginians; wannan shine watakila yaƙin jirgin ruwa mafi girma a tarihi ta yawan mayakan da ke ciki. Farkon mamayewar ya tafi da kyau kuma a cikin 255 BC Carthaginians sun nemi zaman lafiya; Sharuɗɗan da aka gabatar sun kasance masu tsauri da suka yi yaƙi,
cin nasara da mamayewa. Romawa sun aika da jirgin ruwa don kwashe wadanda suka tsira kuma Carthaginians sun yi adawa da shi a yakin Cape Hermaeum daga Afirka; an ci Carthaginians da yawa. A wani ɓangare kuma, guguwa ta halaka rundunar ruwan Romawa sa'ad da suke komawa Italiya, kuma sun yi hasarar yawancin jiragensu da kuma mutane fiye da 100,000.