Kammala wannan jumla: An kori kocin Edoardo Reja a watan Maris na 2009 kuma an nada tsohon kocin kungiyar Italiya Roberto Donadoni a matsayin wanda zai maye gurbinsa. An kore shi a watan Oktoba kuma tsohon kocin Sampdoria Walter Mazzarri ya maye gurbinsa. A karkashin Mazzarri, Napoli ya hau kan teburin, ya gama a matsayi na shida don cancanta don UEFA Europa League na 2010-11. Napoli, a karkashin jagorancin Mazzarri da kuma karfafawa ta hanyar 'yan wasa irin su Edinson Cavani, sun shafe wani ɓangare na gasar
2010-11 kakar wasa a matsayi na biyu, kammala na uku kuma ya cancanci kai tsaye zuwa rukunin rukuni na 2011-12 UEFA Champions League.