Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Passage: Acetanilide shine farkon aniline wanda aka samo asali wanda aka gano yana da kayan aikin analgesic da antipyretic, kuma an gabatar da shi cikin hanzari cikin aikin likita a karkashin sunan Antifebrin ta Cahn & Hepp a 1886. Amma illar da ba za a iya yarda da ita ba - wanda ya fi damuwa shine cyanosis saboda methemoglobinemia - ya haifar da neman abubuwan da aka samo daga aniline marasa guba. Harmon Northrop Morse ya riga ya haɗu da paracetamol a Jami'ar Johns Hopkins ta hanyar rage p-nitrophenol tare da tin a cikin acid acetic acid a cikin 1877, amma har zuwa 1887 likitan likitancin likitancin Joseph von Mering ya gwada paracetamol akan mutane. A cikin 1893, von Mering ya wallafa wata takarda da ke ba da rahoto game da sakamakon asibiti na paracetamol tare da phenacetin, wani kayan aniline. Von Mering ya yi iƙirarin cewa, ba kamar phenacetin ba, paracetamol yana da ƙananan hali don samar da methemoglobinemia. Paracetamol an yi watsi da shi da sauri don son phenacetin. Tallace-tallace na phenacetin sun kafa Bayer a matsayin babban kamfanin magunguna. An rufe shi a wani ɓangare ta hanyar aspirin, wanda Heinrich Dreser ya gabatar a cikin magani a 1899, phenacetin ya shahara har tsawon shekaru da yawa, musamman a cikin " gaurayewar ciwon kai " da aka tallata a ko'ina, yawanci yana dauke da phenacetin, wani aminopyrine wanda aka samo daga aspirin, maganin kafeyin, da kuma wani lokacin barbiturate. Paracetamol shine mai aiki na aiki na phenacetin da acetanilide, dukansu sun kasance sanannun magungunan analgesics da antipyretics a kansu. Koyaya, ba kamar phenacetin, acetanilide da haɗuwa da su ba, ba a ɗaukar paracetamol a matsayin mai cutar kansa a allurai na warkewa. Da'awar Von Mering ta kasance ba ta da ƙalubale har tsawon rabin ƙarni, har sai ƙungiyoyin masu bincike biyu daga Amurka sun bincika metabolism na acetanilide da paracetamol. A cikin 1947 David Lester da Leon Greenberg sun sami tabbaci mai ƙarfi cewa paracetamol babban metabolite ne na acetanilide a cikin jinin ɗan adam, kuma a cikin wani binciken da ya biyo baya sun ba da rahoton cewa manyan allurai na paracetamol da aka ba berayen albino ba su haifar da methemoglobinemia ba. A cikin...  Tambaya: A wane lokaci ne aka saka paracetamol a cikin littafin magunguna na Birtaniya?
Shekara ta 1963