Kamar yadda yake tare da kowane magani, akwai yiwuwar alluran rigakafi su haifar da mummunan sakamako, kamar mummunan halayen rashin lafiyar jiki, amma ba kamar sauran magungunan likita ba, ana ba da alluran rigakafi ga mutanen da ke da lafiya kuma saboda haka ana sa ran mafi girman aminci. Duk da yake mawuyacin haɗari daga allurar rigakafi suna yiwuwa, suna da wuya sosai kuma sun fi yawa fiye da haɗarin irin wannan daga cututtukan da suke hanawa. Yayin da nasarar shirye-shiryen rigakafi ke ƙaruwa kuma yawan cututtukan cututtuka ya ragu, hankalin jama'a ya canza daga haɗarin cutar zuwa haɗarin allurar rigakafi, kuma ya zama abin ƙalubale ga hukumomin kiwon lafiya na gaba don kiyaye lafiyar jama'a don shirye-shiryen allurar rigakafi.
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