Kammala wannan jumla: A shekara ta 2001, Wagner ya zama shugaban kwamitin kwamitin Republican National Committee kuma ya taimaka wajen shugabancin majalisar wakilai na Republican.
Taron Jam'iyyar Republican na shekara ta 2004. A wannan matsayin, ta taka muhimmiyar rawa wajen jagorantar ci gaban shirin Mata Masu Nasara, wanda burin sa shi ne inganta hoton GOP tare da mata da kuma nuna mahimmancin dandalinsa a gare su. Aikinta tare da kwamitin ya kai ta jihohi 48. A watan Janairun 2005, ta bar matsayinta na co-shugaban bayan wa'adi daya.