nucleases da cewa hydrolyse nucleotides daga iyakar DNA strands ake kira exonucleases, yayin da endonucleases yanke a cikin strands. A mafi yawan amfani da nucleases a kwayoyin ilmin halitta ne ƙuntatawa endonucleases, wanda yanke DNA a takamaiman jerin. Alal misali, da EcoRV enzyme aka nuna a hagu gane 6-base jerin 5′-GATC-3′ da kuma sa a yanke a kwance line. A cikin yanayi, wadannan enzymes kare kwayoyin cuta da phage kamuwa da cuta ta narkar da phage DNA lokacin da ta shiga kwayar kwayar cuta, a matsayin wani ɓangare na ƙuntatawa tsarin. A jerin fasahar, wadannan nucleases-takama ana amfani da kwayoyin cloning DNA da kuma sawun yatsa tambaya: Abin da irin kwayoyin macromoleases ne?
ƙwayoyin cuta