Kammala jumlar da ke gaba: A matakin kasa da kasa, Pirlo ya buga wasanni 116 don kungiyar kwallon kafa ta Italiya, wanda shine na biyar mafi yawa a kowane lokaci. Ya fara wasan farko a shekarar 2002, kuma ya jagoranci kasarsa zuwa lambar tagulla a wasannin Olympics na 2004. Pirlo ya taka muhimmiyar rawa a nasarar da Italiya ta samu a gasar cin kofin duniya ta FIFA ta 2006, inda ya lashe Kwallon tagulla kuma aka zaɓe shi a cikin Team of the Tournament. Ya maimaita irin wannan nasarar yayin da ya jagoranci Italiya zuwa wasan karshe na gasar zakarun Turai ta 2012. Pirlo ya kuma wakilci kasarsa a gasar cin kofin duniya.
Gasar zakarun Turai ta 2004 da 2008, da 2010 da 2014 FIFA World Cups, da kuma 2009 da 2013 FIFA Confederations Cups.