Ka kammala wannan magana: Van der Breggen ya zama kwararre a 2012 tare da. A watan Afrilu, ta ɗauki matsayi na tara a Tour of Flanders, kuma a watan Yuli, ta lashe Tour de Bretagne Féminin. Ta lashe uku daga cikin matakai huɗu kuma ta tabbatar da cikakken rarrabuwa tare da kusan minti uku na jagoranci akan Sofie De Vuyst. Ta kuma lashe gasar tseren lokaci a Tour Féminin en Limousin da kuma lambar zinare a gasar tseren lokaci ta mata 'yan kasa da shekaru 23 a gasar cin kofin duniya ta Tour de France.
Gasar zakarun Turai. A sakamakon haka, an zaɓe ta don Gasar Cin Kofin Duniya ta 2012. Yayin da take taka rawar gani ga shugaban kungiyar ta, Marianne Vos, ta yi nasarar kammala ta biyar a tseren hanya.