Cika wannan jumla: Inter Milan ta fara wasan
2015-16 kakar wasa tare da nasara 1-0 a gida a kan Atalanta, inda Handanović ya ci gaba da kasancewa mai tsabta a kakar wasa ta bana. A ranar 27 ga Satumba, 2015, a wasan sa na 300 na Serie A, da Fiorentina, Handanović ya yi watakila mafi munin bayyanarsa ta hanyar ba da hukuncin da Josip Iličić ya zira a minti na 3, daga baya Nikola Kalinić ya doke shi sau uku a cikin asarar 1<unk>4. Rashin nasarar ya kawo karshen rashin nasarar Inter a kakar 2015-16. Bayan wasan, Handanović ya gaya wa manema labarai cewa laifinsa ne yadda wasan ya ƙare.