A cikin 1878, Nietzsche ya yi aiki a cikin wani sabon salon, wanda ya ci gaba da rinjayar tunanin Afrikan Spir da Gaskiya kuma ya yi tsayayya da falsafar pessimistic na Wagner da Schopenhauer. Abokan Nietzsche tare da Deussen da Rohde sun yi sanyi. A 1879, bayan da ya ragu sosai a cikin kiwon lafiya, Nietzsche ya yi murabus da matsayinsa a Basel. Tun lokacin yaro, cututtuka daban-daban sun shafe shi, ciki har da lokuta na rashin gani wanda ya bar shi kusan makanta, ciwon kai na migraine, da kuma mummunan rashin abinci.
cututtuka daban-daban masu lalatawa