Afua Nkulenu an haife ta ne a Yankin Volta ga George Nkulenu, wani maƙerin ƙarfe, da matarsa Georgina, mai tukwane da manomi, dukansu mutanen Ewe. Uwargidanta ta tura ta zuwa makarantar firamare ta Presbyterian, yarinyar ta ci gaba zuwa makarantar kwana ta coeducational a Peki Blengo. Saboda talauci, tana tafiya mako-mako daga gida zuwa makaranta, tana ɗaukar kayan abinci kowane mako wanda ta dafa wa kanta don guje wa kashe kuɗi. Lokacin da ta sami tallafin karatu a Makarantar Achimota, mahaifiyarta ta ba ta kuɗi don zuwa makarantar. Ta yi karatu a can daga 1936 zuwa 1941, lokacin da ta sami Takardar shaidar Makarantar Cambridge. Tambaya: A ina aka haifi Afua Nkulena?
Yankin Volta