Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Passage: An gano cutar ta Alzheimer a matsayin cutar da ba ta dace ba ta furotin (proteopathy), wanda ke haifar da tarkace na tarin furotin amyloid beta da furotin tau a cikin kwakwalwa. Plaques an yi su ne da ƙananan peptides, 39<unk>43 amino acid a tsawon, wanda ake kira amyloid beta (Aβ). Aβ wani yanki ne daga babban furotin na amyloid precursor (APP). APP shine furotin na transmembrane wanda ya shiga cikin membrane na neuron. APP yana da mahimmanci ga haɓakar neuron, rayuwa, da gyaran bayan rauni. A cikin cutar Alzheimer, gamma secretase da beta secretase suna aiki tare a cikin tsarin proteolytic wanda ke haifar da APP ya kasu kashi-kashi. Ofaya daga cikin waɗannan gutsuttsarin yana haifar da fibrils na amyloid beta, wanda daga baya ya zama ƙwayoyin da ke ajiyewa a waje da ƙwayoyin cuta a cikin ɗakunan da aka sani da plaques.AD kuma ana ɗaukar tauopathy saboda haɗuwa da ƙwayoyin tau na al'ada. Kowace ƙwayar cuta tana da tsarin da ake kira cytoskeleton, wanda ya ƙunshi ƙananan ƙwayoyin cuta da ake kira microtubules. Waɗannan ƙananan ƙwayoyin suna kama da hanyoyi, suna ja-gorar abubuwan gina jiki da ƙwayoyin halitta daga jikin kwayar halitta zuwa ƙarshen axon da kuma baya. Protein da ake kira tau yana daidaita microtubules lokacin da aka phosphorylated, sabili da haka ana kiransa furotin mai alaƙa da microtubule. A cikin AD, tau yana fuskantar canje-canje na sinadarai, ya zama hyperphosphorylated; sannan ya fara haɗuwa da wasu zaren, ƙirƙirar ƙwayoyin neurofibrillary da rushe tsarin jigilar neuron. Pathogenic tau kuma na iya haifar da mutuwar neuronal ta hanyar rashin daidaituwa na abubuwan da aka sanya.  Tambaya: menene wani sunan da aka ba wa furotin da ke phosphorylated?
furotin mai alaƙa da microtubule