Rubuta ci gaba don wannan sakin layi - A ranar 26 ga Mayu 2015, an tabbatar da Ambríz a matsayin sabon manajan a Club América, yana sanya hannu kan kwangilar shekara biyu. Ya jagoranci América zuwa wani abin takaici a gasar cin kofin duniya ta FIFA, inda ya yi rashin nasara a wasan kusa da na kusa da na karshe da kungiyar Guangzhou Evergrande ta kasar Sin ta yi, kuma ya doke kungiyar kwallon kafa ta kasar Congo TP Mazembe don samun matsayi na biyar a gasar. A shekara mai zuwa, Ambríz ya jagoranci América zuwa wasan karshe na CONCACAF Champions League, inda ya doke Tigres UANL 4<unk>1 a kan jimlar, don haka ya sami cancantar zuwa gasar cin kofin duniya ta 2016.
Ka yi haƙuri. A watan Satumba, an sanya shi a matsayin na 10 mafi kyawun koci bisa ga "Football Coach World Ranking". A ranar 17 ga Satumba, bayan shan wahala a gida 2 <unk> 0 a hannun León, an kori Ambríz a matsayin koci a washegari.