Rubuta ci gaba don wannan sakin layi - Musulmai sun canza rabin Cocin St. John zuwa Masallacin Juma'a na birni (Babban Masallacin al-Nuri) kuma Homs ba da daɗewa ba ya zama cibiyar addinin Islama tun lokacin da wasu sahabbai 500 na Muhammad suka zauna a can bayan cin nasara. Kaburburan Khalid ibn al-Walid, ɗansa Abd al-Rahman, da Ubayd Allah, ɗan Halifa Umar suna cikin birni. A lokacin rikici
tsakanin Umayyads da Ali, mazaunan Homs sun hada kai da Ali kuma lokacin da aka ci nasara, Umayyad halifa Mu'awiyah ya raba rabin arewacin Jund Hims don samar da wani yanki na musamman, Jund Qinnasrin, a fili a matsayin horo. Gidan jawabi na Ali ("mash-had 'Ali") yana cikin birni, kuma al'adar Islama ta yi iƙirarin cewa an zana yatsunsa a kai. Duk da zalunci da Umayyads suka yi, Homs ya kasance cibiyar addinin Shi'a na ɗan lokaci. A matsayin sansanin Banu Kalb, garin ya shiga cikin rikice-rikicen na baya-bayan nan tare da bangaren kabilun Qays. Khalifan Umayyad na ƙarshe, Marwan II, ya sami goyon bayan Qais kuma daga baya ya rushe ganuwar birni don mayar da martani ga tawayen Banu Kalb.