Lokacin da sauran macrophages kai farmaki da kamuwa da macrophage, suka fused tare da samar da wani giant multinucleated cell a cikin alveolar lumen. granuloma iya hana yaduwar mycobacteria da kuma samar da wani gida yanayi domin hulda da Kwayoyin na rigakafi tsarin. Duk da haka, mafi yawan 'yan kwanan nan shaida ya nuna cewa kwayoyin amfani da granulomas don kauce wa hallaka ta hanyar da garkuwar jiki ta rigakafi tsarin.
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