MHC: antigen hadaddun yana kuma gane da mataimaki cell ta CD4 co-receptor, wanda recruits kwayoyin ciki da T cell (misali, Lck) da suke da alhakin T cell ta kunnawa. Mataimaki T Kwayoyin da weaker tarayya da MHC: antigen hadaddun fiye da lura ga kisa T Kwayoyin, ma'ana da yawa masu karɓa (a kusa da 200<unk>300) a kan mataimaki T cell dole ne a daura da wani MHC: antigen domin kunna mataimaki cell, yayin da kisa T Kwayoyin za a iya kunna da alkawari guda na wani MHC: antigen kwayoyin. Mataimaki T cell kunnawa kuma ya fi tsayi na alkawari da wani antigen-presenting cell kunnawa. The kunnawa na mataimaki cell ta CD4 co-receptor, wanda recruits kwayoyin ciki da T cell (misali, Lck) da suke da alhakin T cell ta kunnawa. Mataimaki T Kwayoyin suna da wani weaker tarayya da MHC: antigen hadaddun fiye da lura ga kisa T Kwayoyin, ma'ana da yawa a kan mataimaki T cell surface
Kwayoyin MHC na aji na II