Rubuta ci gaba don wannan sakin layi - Wilson ya jagoranci Dreyer & Reinbold Racing (DRR) No. 22 mota a cikin kakar 2010. Rashin jituwa kan tsawon kwantiraginsa da DCR, ficewar manyan ma'aikatan kungiyar da kuma sha'awar wata gogewa ta sa ya tantance tuki a wani wuri. Wilson ya sami kiran waya daga Dreyer &amp; Reinbold masu haɗin gwiwar Robbie Buhl da Dennis Reinbold kuma sun ziyarci aikin su a watan Janairun 2010. Abin da ya gani ya burge shi sosai kuma ba da daɗewa ba ya shiga ƙungiyar. Wilson ya jagoranci abokin aikinsa Mike Conway a kan tseren tseren tsere kuma ya shawarci DRR a kan hanyoyin hanya. A cikin tsere huɗu na farko ya gama na biyu a Grand Prix na St. Petersburg da Grand Prix na Long Beach. Bayan da ya cancanci 11 ga Indianapolis 500
, Wilson ya jagoranci zagaye goma sha ɗaya kuma ya ɗauki na bakwai. Gasar tsere huɗu daga baya, ya ɗauki matsayinsa na farko na IndyCar don Honda Indy Toronto. Sauran lokacin Wilson ya gan shi ya sami mafi kyawun na shida a Indy Grand Prix na Sonoma. Ya kasance na 11 a matsayin direbobi tare da maki 361.