An gano shi a 1986, activin yana haɓaka FSH biosynthesis da ɓoyewa, kuma yana shiga cikin tsarin tsarin hawan haila. An gano wasu ayyuka da yawa da ake amfani da su ta hanyar activin, ciki har da rawar da ke cikin yaduwar kwayar halitta, bambancin, apoptosis, metabolism, homeostasis, amsawar rigakafi, gyaran rauni, da aikin endocrine. A akasin wannan, inhibin yana rage haɓakar FSH kuma yana hana ɓoyewar FSH. An yi tunanin wanzuwar inhibin tun farkon 1916; duk da haka, ba a wanzu ba har zuwa aikin Schenawartz da Cornelia Channing a tsakiyar shekarun 1970s, bayan da aka bayyana sunadaran kwayoyin biyu.
ƙwayoyin halitta