zuwa ga sashi a kasa sannan kuma amsa tambaya a baya a cikin wannan harshe kamar yadda sashi: Passage: De novo kira na ceramide yana farawa tare da condensation na palmitate da serine don samar da 3-keto-dihydrosphingosine. Wannan halayen yana ƙaddamar da enzyme serine palmitoyl transferase kuma shine matakin ƙayyadadden hanya. A gefe guda, 3-keto-dihydrosphingosine ya rage zuwa dihydrosphingosine, wanda aka bi da acylation ta hanyar enzyme (dihydro) ceramide synthase don samar da dihydroceramide. Sakamakon karshe don samar da ceramide an ƙaddamar da dihydroceramide desaturase. De novo kira na ceramide yana faruwa a cikin endoplasmic reticulum. Ceramide daga bisani an kai shi zuwa ga vesicular ta hanyar zirga-zirga ko ceramingolipid ko ceramingolipid.
(dihydro) ceramide synthase