Duk da haka, kamar yadda Parthia fadada yamma, suka zo a cikin rikici da Kingdom of Armenia, kuma a karshe marigayi Roman Republic. Roma da Parthia gasar da juna don kafa sarakunan Armenia kamar yadda su subordinate abokan ciniki. The Parthia soundly kayar Marcus Licinius Crassus a Battle of Carrhae a 53 BC, kuma a 40<unk>39 BC, Parthia sojojin kama dukan na Levant daga Romawa. Duk da haka, Mark Antony ya jagoranci wani counterattack da Parthia, ko da yake ya nasarorin da aka kullum samu a cikin rashi, a karkashin shugabancin ya lieutenant Ventidius.
Seleucids