Passage: Babban isoform na mutum girma hormone ne mai gina jiki na 191 amino acid da kwayoyin nauyi na 22,124 daltons. Tsarin ya hada da hudu helices zama dole ga aikin hulda da GH receptor. Ya bayyana cewa, a cikin tsarin, GH ne evolutionarily homologous to prolactin da chorionic somatomammotropin. Duk da m tsarin kama tsakanin girma hormone daga daban-daban jinsunan, kawai mutum da kuma Old World biri girma hormones da muhimmanci effects a kan mutum girma hormone receptor. Da dama kwayoyin isoforms na GH wanzu a cikin pituitary gland da ake saki zuwa jini. A musamman, wani bambance-bambancen na kimanin 20 kDa samo asali daga wani madadin splicing ne a cikin wani m 1: 9 rabo, yayin da wani ƙarin bambance-bambancen na ~ 23-24 kDa wanda aka kuma ruwaito a cikin post-growth states a mafi girma rabo. Wannan bambance-bambancen da aka gano, amma ba a gano, shi ne wani bambance-bambancen da aka haɗa da glycosylglycoside hormone, wani ɓangare na kwayoyin girma hormone, wanda aka samu
GH