Rubuta ci gaba don wannan sakin layi - Wani memba na Byzantine mai daraja da kuma dan uwan sarakuna Isaac II Angelos da Alexios III Angelos, Kamytzes ya yi aiki a matsayin babban kwamandan soja a cikin Balkans, tare da matsayin "protostrator", daga 1185/86 har zuwa 1199. Don Isaac II ya yi yaƙi da masu mamaye Norman a 1185 da kuma tayar da hankalin Alexios Branas a 1186/87. Kamytzes sau biyu ya yi yaƙi da tawayen Vlach-Bulgarian
a arewacin Balkans, kazalika da Cuman Raiders a cikin wannan yankin. A cikin 1189, ya yi karo da rukunin Jamusawa na Crusade na Uku, a ƙarƙashin Frederick I Barbarossa, yayin da suka ƙetare yankin Byzantine.