Kammala jumla mai zuwa: Bayan mutuwar &lt;a href="HIV/AIDS"&gt; HIV/AIDS&lt;/a&gt; mai magana da yawun kuma aboki Ryan White a 1993, Jackson ya yi amfani da shahararsa don kawo hankalin duniya ga cutar kanjamau, musamman ta hanyar abokantaka da Ryan da kuma kokarinsa na sadaka tare da Elizabeth Taylor. Michael ya kuma roki gwamnatin Clinton a
Taron bikin rantsar da Bill Clinton don ba da ƙarin kuɗi ga ayyukan agaji na HIV / AIDS da bincike, kuma ya yi "Gone Too Soon", waƙar da aka keɓe wa White, da "Cire Duniya" a bikin. A Janairu 1994, Jackson "ya buɗe Neverland Ranch a bikin bikin ranar haihuwar Martin Luther King ga yara 100 na cikin gari waɗanda suka yi fice a makaranta". A shekara ta 1995, bayan ya karanta rahotanni a jarida game da mutuwar wani yaro ɗan wata 22, Jackson ya ba da gudummawar kuɗi da ba a ambata ba ga asusun da aka kafa a ƙarƙashin kulawar Cibiyar Kiwon Lafiya ta St. Mary a Long Beach, California. A farkon mai goyon bayan 'yancin' yan luwadi, a watan Fabrairun 1997, Jackson ya ba da kyautar jaket na HIStory Tour da littafin kyauta na kyauta don tallafin kuɗi don tallafawa bikin farko na Gay da Lesbian na Hawaii.