A cikin wadanda ke da kwayar cutar HIV, hadarin kamuwa da cutar tarin fuka mai aiki yana ƙaruwa zuwa kusan 10% a shekara. Idan ba a ba da magani mai inganci ba, yawan mace-mace ga masu cutar tarin fuka mai aiki ya kai kashi 66%. Cutar tarin fuka ta fara ne lokacin da mycobacteria suka isa alveolar air sacs na huhu, inda suke mamayewa da kuma ninkawa a cikin endosomes na alveolar macrophages. Macrophages sun gano kwayar cuta a matsayin baƙon abu kuma suna ƙoƙarin kawar da ita ta hanyar phagocytosis. A yayin wannan tsari, kwayar cuta ta rufe ta ta ta hanyar macrophage kuma an adana shi a cikin wani membrane mai ɗaure na wucin gadi wanda ake kira phagosome.
10% a kowace shekara