A shekara ta 1989, Farfesa a fannin ilimin hauka John Olney ya ruwaito cewa ketamine ya haifar da sauye-sauye a kananan yankuna biyu na kwakwalwar beraye.
Tabbas, mafi rikitarwa na jumla ita ce "A cikin 1989, farfesa a fannin ilimin halayyar dan adam John Olney ya ba da rahoton ketamine ya haifar da canje-canje marasa ma'ana a cikin ƙananan yankuna biyu na kwakwalwar bera, wanda, duk da haka, yana da bambance-bambance masu mahimmanci a cikin metabolism daga kwakwalwar mutum, don haka bazai iya faruwa a cikin mutane ba. "