Rubuta ci gaba ga wannan sakin layi - Lisle ya shafe shekaru uku masu zuwa tare da rundunar sojojin Royalist da ke Oxford, da farko a matsayin Lieutenant-Colonel na dragoons karkashin Arthur Aston. Ya shiga cikin Oktoba 1642 Battle of Edgehill kuma ya sami suna don ƙarfin zuciya da aminci, an bayar da rahoton cewa ya ƙi ɗaukar makamai a wani lokaci don tabbatar da mutanensa. A shekara ta 1643, ya yi yaƙi a Chalgrove a watan Mayu, ya ji rauni a Newbury na farko
a watan Satumba da kuma ci gaba da colonel jim kadan bayan. Ya jagoranci rundunar soji a Cheriton a watan Maris na 1644 kuma a lokacin yakin da ke yamma ya umurci brigade ko tercio a Cropredy Bridge, Lostwithiel da Newbury na biyu.