Kammala jumla mai zuwa: A ranar 9 ga Fabrairun 1941, Iachino ya jagoranci rundunar sojan Italiya a cikin rashin nasarar bin sojojin Burtaniya na H, bayan da na baya ya harbe Genoa da La Spezia. Ya sake umurni da jirgin ruwa na Italiya a cikin
Yaƙin Cape Matapan (26-29 Maris 1941), wanda ya haifar da babbar rashin nasara da Regia Marina ta taɓa sha wahala; watsi da rahotannin jiragen ruwa na Burtaniya da ke kusa ba daidai ba ne ko ƙari, ya aika da Darakta na 1st Cruiser gaba ɗaya don ceton jirgin ruwa mai suna "Pola", wanda ya haifar da halakar Darakta gaba ɗaya ta hanyar jiragen ruwa uku na Admiral Andrew Browne Cunningham's Mediterranean Fleet. Ayyukansa a lokacin wannan yaƙin sun kasance batun sukar da yawa tun daga wannan lokacin; duk da wannan, ba a sauke Iachino daga umurnin ba.