Kammala jumla mai zuwa: Mutuwar Manuel a ranar 24 ga Satumba, 1180, ta nuna wani juyi a cikin dukiyar Daular Byzantine. Lokacin da Manuel ya mutu, ɗansa Alexios II Komnenos, wanda ke ƙarƙashin kulawar sarauniya Maria, ya gaje shi. Halin da ta nuna ya haifar da fushin jama'a, kuma rikice-rikicen da suka biyo baya, kusan yaƙin basasa, ya ba da dama ga burin dan uwan Manuel, Andronikos I Komnenos (r. 1183<unk>1185), ɗan Ishaku Komnenos. Andronikos ya bar ritaya a cikin 1182, kuma ya yi tafiya zuwa Constantinople tare da rundunar da (a cewar kafofin da ba na Byzantine ba) sun haɗa da ƙungiyoyin musulmai. Zuwansa ya biyo baya da sauri
kisan kiyashi na mazaunan Latin, wanda aka mayar da hankali ga 'yan kasuwa na Venetian waɗanda suka zauna a wasu lambobi a Constantinople. An yi imanin cewa ya shirya guba na 'yar'uwar Alexius II Maria Porphyrogenita da mijinta Renier na Montferrat, kodayake Maria da kanta ta ƙarfafa shi ya shiga tsakani. An ce mai guba shi ne masassaƙin Pterygeonites. Ba da daɗewa ba bayan haka ya sa aka ɗaure Sarauniya Maria sannan aka kashe ta, ta hannun Pterygeonites da "hetaireiarches" Constantine Tripsychos. An tilasta wa Alexios II ya yarda da Andronikos a matsayin abokin aiki a cikin daular, amma an kashe shi; Tripsychos, Theodore Dadibrenos da Stephen Hagiochristophorites ne suka kashe shi. Andronikos, ta hanyar 1183 sarki daya, ya auri Agnes na Faransa, yarinya mai shekaru goma sha biyu wanda aka yi alkawari da Alexios II. Agnes 'yar Sarki Louis VII ne na Faransa da matarsa ta uku Adèle na Champagne. A watan Nuwamba na shekara ta 1183, Andronikos ya haɗu da ƙaramin ɗansa John Komnenos a kan kursiyin.