Bayan da Yakubu da Monod's 1961 Journal of Molecular Biology takarda "Genetic tsari na tsari a cikin kira na sunadarai", McClintock ya rubuta wata kasida ga American Naturalist kwatanta da lac operon da ta aiki a kan sarrafa abubuwa a masara. Ko da a cikin marigayi karni na ashirin, McClintock ta taimako ga ilmin halitta har yanzu ba yadu a gane a matsayin adadin da samuwar kwayoyin regulation. McClintock aka yadu yaba tare da ganowa na gaba transposition bayan da sauran masu bincike gano da tsari a cikin kwayoyin cuta, yeast, da kuma sponges, a farkon shekarun 1960 da kuma wani ra'ayi da ta nuna da Ac / Sponges a farkon shekarun 1970. A lokacin wannan lokaci, masana kimiyya sun nuna cewa Ac / Sponges iya aiki a matsayin wani muhimmin kayan aiki don motsa jiki da kuma motsa jiki a cikin kwayoyin halitta. A ƙarshe, ba a iya amfani da shi a matsayin hanyar da za a iya amfani da shi a matsayin hanyar da za a iya amfani da shi don motsa jiki ba. A cikin wannan lokacin, masana kimiyya sun nuna cewa Ac / Sponges yana da muhimmanci a matsayin hanyar daukan
wani transposon