An haifi Madonna ne ga iyayen Katolika Madonna Louise (née Fortin) da Silvio Anthony "Tony" Ciccone a Bay City, Michigan a ranar 16 ga Agusta, 1958. Iyayen mahaifinta 'yan gudun hijirar Italiya ne daga Pacentro, yayin da mahaifiyarta ke da asalin Faransa-Kanada. Tony ya yi aiki a matsayin injiniyan injiniya ga Chrysler da General Motors. Tun da Madonna yana da sunan mahaifiyarta,' yan uwa sun kira ta "Little Nonni". Madonna daga baya ya yi sharhi game da sunanta, "Ta yaya zan iya zama wani abu sai dai abin da ake kira Madonna?
injiniya mai tsarawa