Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙari Wasu daga cikin wadannan kwayoyin suna da matakan da suka fi girma a cikin kwayoyin microglial fiye da yadda ake tsammani ta hanyar haɗari. Yiwuwar kamuwa da cutar ta fi girma a cikin dangi na mutumin da ke fama da cutar, tare da haɗari mafi girma a tsakanin waɗanda ke da dangantaka ta kusa. A cikin tagwaye iri ɗaya duka suna shafar kusan kashi 30% na lokacin, yayin da kusan kashi 5% na tagwaye marasa daidaituwa da kashi 2.5% na 'yan'uwa suna shafar tare da ƙananan kashi na rabin' yan'uwa. Idan iyayen duka biyu sun kamu da cutar, haɗarin a cikin 'ya'yansu ya ninka na sauran jama'a sau 10. MS kuma ya fi yawa a wasu kabilu fiye da wasu. Takamaiman kwayoyin halittar da aka danganta da MS sun haɗa da bambance-bambance a cikin tsarin antigen na leukocyte na mutum (HLA) - rukuni na kwayoyin halittar a kan chromosome 6 wanda ke aiki a matsayin babban haɗin gwaninta (MHC). An san cewa bambance-bambance a cikin yankin HLA suna da alaƙa da ƙwarewa tun daga shekarun 1980, kuma wannan yanki ɗaya an kuma haɗa shi da ci gaban wasu cututtukan autoimmune kamar su ciwon sukari na I da kuma lupus erythematosus na tsarin. Mafi daidaitattun binciken shine alaƙar tsakanin ƙwayar cuta da yawa da allele na MHC da aka ayyana azaman DR15 da DQ6. Sauran loci sun nuna tasirin kariya, kamar HLA-C554 da HLA-DRB1 * 11. Gabaɗaya, an kiyasta cewa bambance-bambance na HLA suna lissafin tsakanin 20% da 60% na yanayin halittar jini. Hanyoyin kwayoyin zamani (nazarin haɗin gwiwar kwayoyin halitta) sun bayyana aƙalla wasu kwayoyin halittar guda goma sha biyu a waje da HLA locus waɗanda ke ƙara ƙarancin yiwuwar MS.  Tambaya: Menene sunan tasirin kariya wanda ya ƙare da lamba huɗu?
HLA-C554