Kammala wannan jumlar: Wani memba ne na babban masarautar Byzantine kuma dan uwan sarakuna Isaac II Angelos da Alexios III Angelos, Kamytzes ya yi aiki a matsayin babban kwamandan soja a cikin Balkans, tare da matsayin "protostrator", daga 1185/86 zuwa 1199. Don Isaac II ya yi yaƙi da masu mamaye Norman a 1185 da kuma tayar da hankalin Alexios Branas a 1186/87. Kamytzes sau biyu ya yi yaƙi da Vlach <unk> Bulgarian
'yan tawaye a arewacin Balkans, kazalika da Cuman maharan a cikin wannan yankin. A cikin 1189, ya yi karo da rukunin Jamusawa na Crusade na Uku, a ƙarƙashin Frederick I Barbarossa, yayin da suka ƙetare yankin Byzantine.