Kammala jumla mai zuwa: Nasarar Chalamet ta zo ne a cikin 2017 tare da rawar da ya taka a matsayin Elio Perlman a cikin wasan kwaikwayo na Luca Guadagnino "Kira Ni da Sunanka", bayan haka ya bayyana a cikin fina-finai masu zuwa "Hot Summer Nights" da "Lady Bird" da kuma fim din yammacin "Hostiles". Ayyukansa a cikin "Kira Ni da Sunanka" ya sa ya sami lambar yabo ta Academy Award don Mafi kyawun Actor, yana mai da Timothée mai shekaru 22 da haihuwa na uku mafi ƙanƙanta a cikin rukunin kuma mafi ƙarancin ɗan wasan kwaikwayo a duniya.
mafi ƙanƙanta tun lokacin da Mickey Rooney mai shekaru 19 da haihuwa tare da aikinsa a "Babes in Arms" a 1939. Daga nan ya taka rawar Nic Sheff a cikin wasan kwaikwayo "Beautiful Boy" (2018), wanda aka zaɓe shi don lambar yabo ta Golden Globe, lambar yabo ta Screen Actors Guild, da kuma lambar yabo ta BAFTA, duk don Kyauta Mafi Kyawun Mataimakin Actor. A cikin 2019, Chalamet ya fito a cikin fim ɗin Woody Allen na soyayya mai suna "Rana mai ruwan sama a New York". Daga baya a waccan shekarar, Chalamet ya taka rawar Henry V na Ingila da Theodore "Laurie" Laurence a cikin wasan kwaikwayo na zamani "The King" da "Little Women", bi da bi.