Rubuta ci gaba ga wannan sakin layi - Francona ya jagoranci Indians zuwa gasar zakarun Amurka ta tsakiya a shekarar 2016. Kungiyarsa ta shafe tsohuwar kulob dinsa, Boston Red Sox, a wasanni uku a cikin jerin rukuni - wanda ya sami damar shiga cikin ALCS tare da nasara a Fenway Park a ranar 10 ga Oktoba, 2016. A ranar 19 ga Oktoba, 2016, Indians na Francona sun doke Toronto Blue Jays don ci gaba zuwa Wasannin Duniya
, inda Indians suka lashe wasa 1 a kan Chicago Cubs 6-0 don fadada rikodin Wasannin Duniya zuwa 9<unk>0. Ya rasa wasansa na farko na Wasannin Duniya lokacin da Indians suka ci nasara da Cubs a wasa na 2 da ci 5<unk>1. Indians sun lashe wasa na uku a kan Chicago Cubs 1 <unk> 0. Indians sun lashe wasa na 4 a kan Chicago Cubs 7 zuwa 2 don ba Cleveland jagorancin 3 zuwa 1. Indians za su fada ga Cubs 3<unk>2 a wasan 5. Cleveland ya ci gaba da rasa wasa na 6 da ci 9<unk>3, sa'an nan ya rasa 8<unk>7 a cikin 10 innings a Game 7 yana ba Francona asararsa ta farko a gasar cin kofin duniya. A ranar 15 ga Nuwamba, 2016, Francona an nada shi Manajan Wasannin Wasannin Amurka na Shekara a karo na biyu a cikin aikinsa.