Cika wannan jumla: A wasan Olympics na biyu na Coughlin, a Beijing a 2008, ta zama 'yar wasan Amurka ta farko da ta lashe lambobin yabo shida a gasar Olympics daya. An zabe ta a matsayin babban kyaftin din kungiyar 'yan wasan mata na Amurka tare da Dara Torres mai sau biyar da kuma Amanda Beard mai sau hudu. Coughlin ta lashe lambar zinare a tseren mita 100 a baya a waccan gasar Olympics, mace ta farko da ta sami nasarar kare lambar zinare a tsaye a wannan taron. Kirsty Coventry ta zarce ta a wasan kusa da na karshe, za ta dauki azurfa. Tsaye a kan dandalin lambar yabo, leɓen nata har yanzu yana zub da jini bayan ya cije shi a lokacin tseren don janye hankalinta daga ciwon da ke cikin ƙafafunta. Ta lashe lambar azurfa a tseren tseren mita 4×100, tana iyo tare da Lacey Nymeyer, Kara Lynn Joyce da Dara Torres, kuma ta kuma lashe lambar tagulla a tseren mita 200,
4 × 200 mita freestyle relay, da kuma 100 mita freestyle. Ta lashe lambar azurfa a tseren ta na karshe a tseren ninkaya na mita 4 × 100 tare da Rebecca Soni, Christine Magnuson, da Dara Torres.