A 1974 Frank Sherwood Rowland, Farfesa a Chemistry a Jami'ar California a Irvine, da kuma postdoctoral aboki Mario J. Molina nuna cewa tsawon rai kwayoyin halogen mahadi, kamar CFCs, zai iya nuna hali a cikin irin wannan fashion kamar yadda Crutzen ya samarwa ga nitrous oxide. James Lovelock ya kwanan nan gano, a lokacin da wani cruise a kudancin Atlantic a 1971, cewa kusan duk na CFC mahadi kerarre tun da suka samu a 1930 har yanzu suna ba a cikin yanayi. Molina da Rowland kammala da cewa, kamar N2O, da CFCs zai isa cikin stratosphere inda za su dissociated da UV haske, saki chlorine atoms. A shekara a baya, Richard Stolar da Ralph Cicerone a Michigan ya nuna cewa shi ne ma ya fi dacewa fiye da NO a hallaka ozone.
Jami'ar California a Irvine