Kammala jumla mai zuwa: Isla ya fara wasan sa na farko a ranar 19 ga Disamba 2007 da Palermo a Coppa Italia. A ranar 8 ga Maris, 2008, Isla ya buga wasan farko a matsayin mai farawa a Serie A kuma a kan Palermo, wasan da ya ƙare a wasan 1 × 1. Bayan tafiyar Simone Pepe, Isla sau da yawa yana wasa a matsayin mai tsaron baya na dama a cikin tsari na 3<unk>5<unk>2 a lokacin Udinese
2010<unk>11 Serie A kakar, saboda raunin da ya faru na dogon lokaci ga Dušan Basta. A wannan kakar, ya taimaka sosai wajen taimakawa Udinese ya gama na huɗu, don haka ya sami cancanta zuwa zagaye na 2011-12 UEFA Champions League.