Kammala jumla mai zuwa: Kodayake manema labarai sun ba da rahoton cewa Fisher za ta yi gasa a gasar 2010 Honda Grand Prix na St. Petersburg a karon farko tun 2007, ta zaɓi ta daina tseren da kuma Indy Grand Prix na Alabama a Barber Motorsports Park kuma ta maye gurbin kanta da ɗan'uwan ɗan'uwan Amurka Graham Rahal, ta shawo kan babban mai tallafawa cewa Rahal ya dace da ƙungiyarta. Yarjejeniyar tseren biyu ta rage jadawalin Fisher na 2010 daga zagaye tara zuwa bakwai. Don haka, tseren farko na shekarar 2010 ya kasance a Kansas, inda ta gama a 17th bayan mafi kyawun lokacin farawa na 14th. A cikin
Indianapolis 500, Fisher tana da mafi munin farawa na 29th; ta gama tseren 26th bayan an tattara ta a cikin hadarin mota mai yawa na 124. Sakamakon mafi kyau na Fisher na kakar wasa shi ne na 15, wanda ta samu a Texas da kuma a Chicagoland. Ta ƙare kakar wasa tare da gamawa a matsayi na 22 a Homestead-Miami Speedway. Fisher ya kasance na 26 a matsayin direbobi tare da maki 92. Ta nemi direba na cikakken lokaci don maye gurbin ta saboda ta yi tunanin tuki na tafiyar da ita daga iyawarta ta gudanar da ƙungiyar yadda ya kamata. Fisher ta bar budewa cewa har yanzu za ta gudanar da jadawalin lokaci na gaba. A watan Nuwamba, duk da haka, ta sanar da yin ritaya daga tseren, kuma direba Ed Carpenter ya maye gurbin ta a cikin motar No. 67 don kakar 2011.