Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Tafiya: Ba a san ainihin abin da ke jawo ciwon sukari na ciki ba. Alamar GDM ita ce karuwar juriya na insulin. Ana tunanin hormones na ciki da sauran dalilai suna tsoma baki tare da aikin insulin kamar yadda yake ɗaure ga mai karɓar insulin. Wataƙila tsangwama na faruwa ne a matakin hanyar siginar tantanin halitta bayan mai karɓar insulin. Tun da yake insulin yana sa glucose ta shiga cikin yawancin ƙwayoyin halitta, tsayayyar insulin tana hana glucose shiga cikin ƙwayoyin halitta yadda ya kamata. Sakamakon haka, glucose ya kasance a cikin jini, inda matakan glucose suka tashi. Ana buƙatar ƙarin insulin don shawo kan wannan juriya; ana samar da insulin kusan sau 1.5 zuwa 2.5 fiye da yadda ake yi a cikin al'ada na al'ada. Juriya ga insulin abu ne na al'ada wanda ke fitowa a cikin watanni na biyu na ciki, wanda a lokuta na GDM ya ci gaba daga baya zuwa matakan da aka gani a cikin mutumin da ba shi da ciki tare da ciwon sukari na 2. An yi tunanin cewa yana tabbatar da isar da glucose ga tayin da ke girma. Matan da ke da GDM suna da juriya ga insulin wanda ba za su iya biya ba tare da haɓaka samarwa a cikin ƙwayoyin β na pancreas. Hormones na mahaifa, kuma, zuwa ƙarami, ƙaruwar mai mai yawa a lokacin daukar ciki, da alama suna yin sulhu game da juriya na insulin a lokacin daukar ciki. Cortisol da progesterone sune manyan masu laifi, amma lactogen na mutum, prolactin da estradiol suna taimakawa, suma. Nazarin koma-baya na mataki-mataki ya nuna cewa, a hade tare da wasu kwayoyin halittar mahaifa, leptin, tumor necrosis factor alpha, da resistin suna da hannu a cikin raguwar ƙarancin insulin da ke faruwa a lokacin daukar ciki, tare da tumor necrosis factor alpha da aka ambata a matsayin mafi ƙarfi mai hangen nesa na ƙarancin insulin a cikin ciki. Haɗin haɗi tare da canje-canje a cikin ƙwarewar insulin daga lokacin kafin ɗaukar ciki har zuwa ƙarshen ciki yana ɗaukar kusan rabin bambancin raguwar ƙwarewar insulin yayin ciki: a wasu kalmomin, ƙananan matakan ko canjin abubuwan TNF alpha sun dace da mafi girman damar, ko saurin zuwa, juriya na insulin ko...  Tambaya: Wace cuta ce take faruwa a lokacin rabin ciki na biyu?
Juriya ga insulin