A 1884, Faransanci microbiologist Charles Chamberland ƙirƙira wani tace (da aka sani a yau kamar yadda Chamberland tace ko da Pasteur-Chamberland tace) tare da pores karami fiye da kwayoyin. Ta haka ne, ya iya wuce wani bayani dauke da kwayoyin ta cikin tace da kuma gaba daya cire su. A 1892, Rasha masanin ilmin halitta Dmitri Ivanovsky amfani da wannan tace don nazarin abin da yanzu aka sani da taba mosaic cutar. Ya gwaje-gwajen ya nuna cewa crushed ganye tsantsa daga kamuwa da taba shuke-shuke zama m bayan tacewa. Ivanovsky shawara da kamuwa da cuta zai iya zama ta hanyar wani toxin samar da kwayoyin, amma bai bi da ra'ayin. A lokacin da aka yi tunanin cewa duk kamuwa da cuta jamiái za a iya kiyaye ta hanyar kwayar cutar da kwayar cutar a kan wani matsakaici girma fiye da kwayoyin. A farkon karni na 20, Faransanci masanin ilmin halittu Charles Chamberland ƙirƙira wani tace (da aka sani a yau da Chamberland tace ko da kuma Pasteur-Chamberland tace) da aka sani da kwayo
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