Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Hanyar wucewa: GH kuma yana motsawa, ta hanyar hanyar siginar JAK- STAT, samar da insulin-like factor factor 1 (IGF-1, wanda aka fi sani da somatomedin C), hormone mai kama da proinsulin. Hanyoyin hanta shine babban maƙasudin GH don wannan tsari kuma shine babban wurin samar da IGF - 1. IGF-1 yana da tasirin haɓaka haɓaka akan nau'ikan ƙwayoyin cuta masu yawa. Ana samar da ƙarin IGF-1 a cikin ƙwayoyin da aka yi niyya, yana mai da shi abin da ya zama kamar hormone na endocrine da autocrine / paracrine. IGF-1 kuma yana da tasirin motsa jiki akan osteoblast da aikin chondrocyte don inganta ci gaban kashi.Baya ga ƙara tsawo a cikin yara da matasa, hormone girma yana da wasu sakamako da yawa akan jiki:  Tambaya: Mene ne yake da tasiri mai kwakwalwa?
IGF-1 mai haɗari