A cikin 1878, Nietzsche ya yi aiki a matsayin mai ba da shawara a cikin wani littafi mai suna Human, All Too Human (wani littafi na aphorisms daga metaphysics zuwa halin kirki zuwa addini zuwa nazarin jinsi), sabon salon aikin Nietzsche ya zama bayyananne, wanda ya rinjayi tunanin Afrikan Spir da Gaskiya kuma ya yi tsayayya da falsafar pessimistic na Wagner da Schopenhauer. Abokan Nietzsche tare da Deussen da Rohde sun yi sanyi. A 1879, bayan da ya ragu sosai a cikin kiwon lafiya, Nietzsche ya yi murabus da matsayinsa a Basel. Tun lokacin yaro, cututtuka daban-daban sun shafe shi, ciki har da lokutan rashin gani wanda ya bar shi kusan makanta, migraine, ciwon kai da kuma mummunan rashin abinci.
Deussen da Rohde