A shekara ta 1514, Sultan Selim I (1512<unk>1520) ya sami nasarar fadada iyakokin kudanci da gabashin daular ta hanyar kayar da Shah Ismail I na daular Safavid a yakin Chaldiran. A shekara ta 1517, Selim I ya fadada mulkin Ottoman zuwa Algeria da
Misira, da kuma samar da wani sojan ruwa gaban a cikin Red Sea. Daga baya, gasar ta fara tsakanin daular Ottoman da ta Fotigal don zama babban ikon teku a Tekun Indiya, tare da yawan yaƙe-yaƙe na ruwa a cikin Bahar Maliya, Tekun Larabawa da Tekun Fasha. Kasancewar Fotigal a Tekun Indiya an dauke shi a matsayin barazana ga ikon mallakar Ottoman a kan hanyoyin kasuwanci na d ̄ a tsakanin Gabashin Asiya da Yammacin Turai. Duk da kasancewar kasancewar Turai da ke ci gaba, kasuwancin Daular Ottoman tare da gabas ya ci gaba da bunƙasa har zuwa rabi na biyu na karni na 18.