Duba wurin da ke ƙasa sannan ka amsa tambayar daga baya a cikin harshe ɗaya kamar yadda wurin yake:  Bayanin: An sa wa ciwon nan sunan Harry Klinefelter, wanda a shekara ta 1942 ya yi aiki tare da Fuller Albright da kuma E. C. Reifenstein a asibitin Massachusetts General Hospital a Boston, Massachusetts, kuma ya fara bayyana shi a wannan shekarar. Asusun da Klinefelter ya bayar an san shi da cutar Klinefelter kamar yadda sunansa ya fara bayyana a kan takarda da aka buga, kuma ba a sake amfani da dysgenesis na seminiferous tubule ba. Idan aka yi la'akari da sunayen duka masu binciken guda uku, wani lokacin ana kiranta da cutar Klinefelter-Reifenstein-Albright. A shekara ta 1956 an gano cewa cutar ta Klinefelter ta samo asali ne daga karin kwayar halitta. Plunkett da Barr sun sami jikin chromatin na jima'i a cikin kwayar halitta ta jiki. An kara bayyana wannan a matsayin XXY a cikin 1959 ta Patricia Jacobs da John Anderson Strong. Rahoton da aka buga na farko na wani mutum da ke da karyotype 47,XXY shine Patricia Jacobs da John Strong a asibitin Western General a Edinburgh, Scotland, a 1959. An sami wannan karyotype a cikin wani mutum mai shekara 24 wanda yake da alamun KS. Jacobs ta bayyana ganowar wannan aneuploidy na farko da aka ruwaito na mutum ko na dabbobi masu shayarwa a cikin jawabinta na Kyautar William Allan na 1981.  Tambaya: A wace shekara ce Patricia Jacobs da John Anderson Strong suka bayyana chromosome da za a kira XXY?
Shekara ta 1959