Ka cika wannan jumla: Sa'id ya shiga cikin kare gidan Uthman lokacin da 'yan tawayen Masar suka kewaye shi a shekara ta 656. Daga karshe an kashe Khalifan kuma Sa'id ya ji rauni a harin. Bayan haka, an saita shi don shiga Aisha, Talha ibn Ubayd Allah da Zubayr ibn al-Awwam a cikin bin ramuwar gayya game da mutuwar Uthman. Koyaya, ya ƙi yin yaƙi tare da su a kan magajin Uthman, Halifa Ali () a Yaƙin Rakumi. Maimakon haka, ya zauna a Makka. Duk da cewa ba sa shiga cikin
Yaƙi da Ali, Halifa Mu'awiya I (), babban abokin hamayyar Ali, ya nada Sa'id gwamnan Madina a 669. Ya maye gurbin Marwan ibn al-Hakam har sai da aka sake nada shi a mukamin a shekara ta 674.