A cikin wasiƙar, Edward VI ya mutu a ranar 6 ga Yuli, 1553, yana da shekaru 15. Ya yi watsi da Dokar Succession to the Crown Act 1543, ya cire Maryamu da Elizabeth daga gado, kuma a maimakon haka ya bayyana a matsayin magajinsa Lady Jane Grey, jikan 'yar'uwar Henry VIII, Maryamu.
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