Whakarāpopototia te tuhinga:  Inanahi, i whakaputaina e te Mail he whakaahua whakamiharo o te whanau o te kaiwhakaari a Angelina Jolie, e whakaatu ana me pehea te mate o te mate pukupuku ki te maha o ona whanaunga, tae atu ki tona whaea, whaea keke me te kuia. Ko tana whaea, te kaiwhakaari a Marcheline Bertrand, i mate i te mate pukupuku o te ovarian i te 56 o ona tau i te tau 2007. Ko tana kuia a Lois Bertrand i mate i te mate pukupuku i te 45 o ona tau, a, ko tana kuia a Debbie - te tuahine o tona whaea - i hinga i tana pakanga ki te mate i te 61. Ko tēnei hītori kaha o te whānau e ahu mai ana i tētahi rerekētanga o te ira BRCA1, e tino whakanui ana i te tūponotanga o te mate pukupuku ovary me te mate pukupuku uma. Panuku ki raro mō te ataata. I whakapuakina e Angelina kua nekehia atu e ia ana whekau me ana ngongo fallopian, whai muri i te whakawātea ārai rua. Hei ārai i a ia anō i te whai i ngā tapuwae o ōna whanaunga wahine, i whakapuakina e Angelina i te wiki kua hipa kua tangohia e ia ōna kōhungahunga me ōna ngongo fallopian (e 50 ōrau pea te tūponotanga o te mate pukupuku o te kōhungahunga). E rua tau i muri mai i te whakaekenga ārai i te kopu rua nā te mea ka nui ake te mōrea o te mate pukupuku uma. Engari ahakoa e mōhio ana te nuinga o te iwi he nui ake te mōrea o te whakawhanake i ēnei mate pukupuku ka taea te tuku iho, ko te mea kāore i tino mōhiotia, ehara i te mea ko te rārangi wahine anake; ka taea hoki te tuku mai i te taha o tō pāpā o te whānau. Ko Catherine Murley, he kaiwhakahaere tauhokohoko 44-tau-tau mai i Rugby, i riro i a ia te tupono nui o te mate pukupuku o te uma me te mate pukupuku o te ovarian mai i tona papa na te mea he kino o te ira BRCA1. 'Kāore au i mōhio ka taea e koe te tuku iho i te ira o te mate pukupuku uma me te mate pukupuku ovary mai i tētahi whanaunga tāne,' e ai ki a ia. I mōhio noa ia ki te ira BRCA1 hapa i roto i tōna rākau whānau i te Pipiri o te tau kua hipa, i muri i te rongo ohorere mai i tōna pāpā a Mike, 68, he kaiako reti, i muri i ngā tau o te whakapā iti. 'I whiwhi au i tētahi karere mai i taku pāpā e mea ana: "Ka taea e mātou te kōrero?"'e ai ki a ia. I wehe ona maatua i te wha o ona tau, a, i whakatipuhia ia e tana whaea me tana tuahine a Sinead, 40, me tana tuakana a Andrew, 39. 'I taku waea atu ki toku papa i taua ahiahi, ka whakamārama mai ia kua kitea he mate pukupuku ovary i taku whanaunga - te tamahine a tana tuahine, ā, kua kitea e te whānau he...
Ko Catherine Murley, 44, nō Rugby, i whiwhi i te ira BRCA1 mai i tōna pāpā. Kātahi ka tangohia tōna uma, ā, ka tangohia ōna whekau me ōna ngongo fallopian. I whakapuakina e Angelina i te wiki kua hipa, he rite tonu tana mahi pokanga.