I whanau mai a Isaac Newton (i runga i te maramataka Julian, i whakamahia i Ingarangi i taua wa) i te ra Kirihimete, 25 Tihema 1642 (NS 4 Hanuere 1643) "he haora, e rua ranei i muri i te waenganui po", i Woolsthorpe Manor i Woolsthorpe-by-Colsterworth, he kainga i roto i te rohe o Lincolnshire. Ko tona papa, ko Isaac Newton hoki te ingoa, i mate e toru marama i mua atu. I whanau wawe, he tamaiti iti a Newton; i kii tona whaea a Hannah Ayscoughly ka taea e ia te whakauru ki roto i te kapu hau. I te toru o nga tau o Newton, ka marenatia tona whaea ka haere ki te noho ki tana tane hou, te Reverend Barnabas Smith, ka waiho tana tama ki te tiaki o tona whaea whaea, a Margery Ayscough.
Ko tōna kuia o tōna whaea, ko Margery Ayscough