I roto i te 1856 riro Kekulé Privatdozent i te University o Heidelberg. I roto i te 1858 i utua ia rite te ahorangi tonu i te University o Ghent, ka i roto i te 1867 i karangatia ia ki Bonn, i reira i noho ia mo te toenga o tona mahi. I runga i tona whakaaro i runga i te hunga o mua pērā i Williamson, Edward Frankland, William Odling, Auguste Laurent, Charles-Adolphe Wurtz me ētahi atu, ko Kekulé te formulator matua o te ariā o te hanganga matū (1857<unk>58). puta tenei ariā i te whakaaro o te atomic valence, rawa te tetravalence o te waro (e Kekulé mutunga i roto i 1857) me te kaha o te waro ngota ki te hono ki tetahi ki tetahi (whakaputaina i roto i te pepa i 1858), engari i roto i te whakatau i te hononga o te ngota katoa i roto i te ngota organic. i roto i te Archibald Couper, ka karanga ia ki a Bonn i roto i te 1867, i reira i noho ia mo te toenga o tona mahi
hanganga matū