CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase

Trong enzyme học, CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) là một enzyme xúc tác phản ứng hóa học sau CDP-diacylglycerol + sn-glycerol 3-phosphate ⇌ {\displaystyle \rightleftharpoons } CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate Vì vậy, hai cơ chất của enzyme này là CDP-diacylglycerol và sn-glycerol 3-phosphate, trong khi hai sản phẩm là CMP và 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate. Enzyme này thuộc về họ transferase, gồm những enzyme chuyên chuyển hóa các nhóm phosphate thay thế không đạt chuẩn. Tên hệ thống của lớp enzyme này là CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase. Những tên thông thường khác bao gồm glycerophosphate phosphatidyltransferase, 3-phosphatidyl-1'-glycerol-3'-phosphate synthase, CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol, (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase, phosphatidylglycerophosphate synthase, phosphatidylglycerolphosphate synthase, PGP synthase, CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase, CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase, glycerol phosphate phosphatidyltransferase, glycerol 3-phosphate phosphatidyltransferase, phosphatidylglycerol phosphate synthase, phosphatidylglycerol phosphate synthetase, phosphatidylglycerophosphate synthetase, and sn-glycerol-3-phosphate phosphatidyltransferase. Enzyme này tham gia chuyển hóa glycerophospholipid. Bleasdale JE, Johnston JM (1982). “CMP-dependent incorporation of [14C]Glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes”. Biochim. Biophys. Acta. 710 (3): 377–90. doi:10.1016/0005-2760(82)90121-7. PMID 7074121. Hirabayashi T, Larson TJ, Dowhan W (1976). “Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5'-diphospho-1,2-diacyl-sn-glycerol sepharose”. Biochemistry. 15 (24): 5205–11. doi:10.1021/bi00669a002. PMID 793612. Bản mẫu:Kinases Bản mẫu:Enzymes Cổng thông tin Sinh học Bản mẫu:2.7-enzyme-stub