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My investment account is increasingly and significantly underperforming vs. the S&P 500. What should I do?
The majority (about 80%) of mutual funds are underperforming their underlying indexes. This is  why ETFs have seen massive capital inflows compared to equity funds, which have seen significant withdrawals in the last years.  I would definitively recommend going with an ETF. In addition to pure index based ETFs that (almost) track broad market indexes like the S&P 500 there are quite a few more "quant" oriented ETFs that even outperformed the S&P. I am long the S&P trough iShares ETFs and have dividend paying ETFs and some quant ETFS on top (Invesco Powershares) in my portfolio.