*        Dynamics of fast-folding proteins to make the connection between experiment and physics-based computer simulations of protein folding.
*        FreI (Fast Relaxation Imaging) that combines fluorescence microscopy and fast temperature jump or osmotic pressure jump to study protein dynamics inside living cells and living animals.
*       A sub-microsecond pressure jump technique to study fast protein refolding and help guide computer simulations (molecular dynamics) for how proteins fold.
* 	With Martina Havenith, Kinetic Terahertz Absorption Spectroscopy elucidating the role of long-range interactions of water with biomolecules.
* 	Two-state dynamics recorded on glass surfaces using time-resolved Scanning Tunneling Microscopy, to measure the size and heterogeneous dynamics of cooperatively rearranging regions on a glass.
* 	SMA-STM (Single Molecule Absorption detected by Scanning Tunneling Microscopy), a technique that can image excited state orbitals of nanostructures with sub-nanometer position resolution  and sub-picosecond time resolution.
* 	With Stephen Boppart, non-linear interferometric vibrational imaging which produces easy-to-read, color-coded images of tissue, outlining clear tumor boundaries with more than 99% confidence.
* 	Computational and theoretical work in the area of quantum energy flow, quantum computation, and quantum information, as well as fundamental transport theory and computation.