His ongoing research interests have centered on the development of new NMR methods for the characterization of impurities and degradants of pharmaceuticals focusing on the exploration of new NMR probe technologies for the characterization of extremely small samples using heteronuclear 2D-NMR methods.  His interests in this area were pivotal in the development of 3 mm and 1.7 mm probe technologies and he was also an early proponent of cryogenic probe capabilities.,
He has had a long-standing interest in heteronuclear NMR and 2D long-range heteronuclear shift correlation in particular.  He was among the first to exploit natural abundance long-range 1H-15N heteronuclear shift correlation experiments, those early reports leading to hundreds of published reports that are the subject of multiple reviews and chapters., More recently, his research interests have also led to the development of unsymmetrical indirect covariance NMR processing methods that have the potential for significant spectrometer time savings when experimental access to hyphenated 2D NMR.  These methods also provide access to 13C-15N Heteronuclear Single Quantum Coherence-Heteronuclear Multiple Bond Coherence (HSQC-HMBC) correlation data that are experimentally inaccessible at natural abundance, and to HSQC-ADEQUATE correlation plots that allow carbon-carbon connectivity networks of molecules to be mapped without having to resort to the highly insensitive 13C-13C INADEQUATE experiment.
In recent years Martin has extended his work into the application of residual dipolar couplings, residual chemical shift anisotropy and   
DFT calculations to demonstrate that, in combination, some of the most complex chemical structures could be elucidated and making unambiguous assignment essentially difficult or impossible.