* 2024, Alfred Burger Award in Medicinal Chemistry from the American Chemical Society
* 2017, Award for Computers in Chemical and Pharmaceutical Research from the American Chemical Society
* 2013, Alumni Association Award from Carleton College
* 2009, Herman Skolnik Award from the American Chemical Society
* 2005, Society for Biomolecular Screening Accomplishment Award
* 2000, fellow, International Union of Pure and Applied Chemistry (IUPAC)
* 1985, fellow, American Association for the Advancement of Science (AAAS)
* Lifetime member of the Molecular Modeling and Graphics Society (MMGS)
* American Crystallographic Association (ACA)