James Andrew McCammon (born 1947, Lafayette, Indiana, US) is an American physical chemist known for his application of principles and methods from theoretical and computational chemistry to biological systems. A professor at the University of California, San Diego, McCammon's research focuses on the theoretical aspects of biomolecular and cellular activity. In 2011 he was elected to the National Academy of Sciences.
Prof. McCammon co-authored Dynamics of Proteins and Nucleic Acids (Cambridge University Press, 1987; ), an important contribution to molecular mechanics and molecular dynamics, with Stephen Harvey, while the first published reports on molecular mechanics and molecular dynamics can be found as early as 1976, most likely even earlier.