Marta Filizola is a computational biophysicist who studies membrane proteins. Filizola's research concerns drug discovery the application of methods of computational chemistry and theoretical chemistry to biochemical and biomedical problems.
Filizola is the dean of the graduate school of biomedical sciences at the Icahn School of Medicine at Mount Sinai in New York City. Where she is a professor of pharmacological sciences and neuroscience, and also the Sharon and Frederick A. Klingenstein-Nathan G. Kase, MD Professor.
She is best known for her work aimed at providing mechanistic insight into the structure, dynamics, and function of G protein-coupled receptors using methods such as molecular modeling, bioinformatics, cheminformatics, enhanced molecular dynamics simulations, and rational drug design approaches. The Filizola laboratory's research has steadily been funded by the National Institutes of Health (NIH) since 2005.
As of 2016, Filizola is active in five research projects funded by the National Institute on Drug Abuse (NIDA), the National Institute of Mental Health (NIMH), and the National Heart, Lung, and Blood Institute (NHLBI).