Multi-layered OFM devices, reinforced with synthetic polymer were first described in 2008 and in the scientific literature in 2010. These devices, termed ‘reinforced biologics’ have been designed for applications in the surgical repair of hernia as an alternative to synthetic surgical mesh (a mesh prosthesis). OFM reinforced biologics are distributed in the US by Tela Bio Inc. Clinical studies have shown that OFM reinforced biologics have lower hernia recurrence rates versus synthetic hernia meshes or biologics such as acellular dermis.