Rui Luís Reis (born 19 April 1967) is a Portuguese scientist known for his research in tissue engineering, regenerative medicine, biomaterials, biomimetics, stem cells, and biodegradable polymers.
Reis is a professor of at the University of Minho in Braga and Guimarães. He is the Founding Director of the 3Bs Research Group, part of the Research Institute on Biomaterials, Biodegradables and Biomimetics (I3Bs) of UMinho (www.i3bs.uminho.pt), a group that specializes in the areas of Regenerative Medicine, Tissue Engineering, Stem Cells and Biomaterials. He is also the Director of the ICVS/3Bs Associate Laboratory of UMinho. He is the CEO of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. Rui L. Reis was, from 2013 to 2017, the Vice-Rector (vice-president) for research and innovation of UMinho. From 2007 to 2021 Reis was the editor-in-chief of the Journal of Tissue Engineering and Regenerative Medicine. From 2016 to 2018, he was president of the Tissue Engineering and Regenerative Medicine International Society (TERMIS).
Reis is in the board of several scientific societies, companies and associations. From 2017 to 2019, he was the President of TECMINHO - the technology transfer office of the University of Minho. 
Reis is the CEO of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine in Avepark, Guimarães.
He co-founded different start up companies originating from the research and activities of 3B's research group, such as Stemmatters and HydruStent/HydruMedical.
Reis is the current president of the I3B's research institute, and one of the most cited Portuguese researchers in science.