* A fake acid attack between rivals for a husband appears in Cecil B. DeMilles film Why Change Your Wife?' (1920).
* In "The Adventure of the Illustrious Client" by Sir Arthur Conan Doyle, the villainous Baron Adelbert Gruner has oil of vitriol thrown in his face by a wronged former mistress, disfiguring him. She is prosecuted for this but given the minimum sentence due to extenuating circumstances.  
* DC Comics supervillain Two-Face's origin stories feature half his face disfigured with acid.
* In the 2002 series of He-Man and the Masters of the Universe, Skeletor owes his namesake skeletal face to an acid attack.
*Saving Face – A 2012 documentary film by Sharmeen Obaid Chinoy and Daniel Junge that follows Pakistani/British plastic surgeon Dr. Mohammad Jawad to his native Pakistan to aid women who were victims of acid attacks, and examines the Pakistani parliament's exercise in banning the act of acid burning. The film won the 2012 Academy Award for best Documentary Short.
* In Emmerdale, one of the characters, Ross Barton, is a victim of an acid attack (as depicted in a 2018 episode). The actor who portrayed Ross Barton has said that it was his idea that the character should be a victim of an acid attack, as he wanted to create an awareness campaign about this problem.
*Surkh Chandni – A 2019 Pakistani television series directed by Shahid Shafaat that follows the story of a girl who survived an acid attack and the harshness of society she has to face there after.
*Dirty God – a 2019 English film starring Vicky Knight as an acid attack victim seeking justice and healing. Knight is a real burn victim, although from a domestic fire rather than an acid attack.
* Infinite Jest – a 1996 novel featuring a scene in which Joelle Van Dynes mother tries to throw acid in her husbands face after he confesses his love for their daughter, Joelle, but instead misses and hits her.
* Uyare – a 2019 Indian Malayalam-language film focuses on an aspiring pilot, who is a victim of an acid attack and how the situation changes around her.
* Chhapaak – a 2020 Indian Hindi-language film based on the life of Laxmi Agarwal, an acid attack survivor.
* In Bergen – a 2022 biopic about Turkish singer Bergen, the acid attack that left her blind in one eye is depicted.
* In Coronation Street in 2023, two characters, Daisy Midgeley and Ryan Connor are victims of an acid attack when Daisy’s stalker, Justin attacks her with acid. Ryan jumps in between Daisy and Justin and receives more severe burns to his face while Daisy only receives moderate burns on her body.
* In Top Boy in 2019, a minor character is depicted being wrestled to the ground and doused with a bottle of unknown acid on his face in a gang attack orchestrated by a main character, Jamie. The victim is then shown at the end of the season wearing an eyepatch with burns on his face. He was also seen in the following season, also with an eyepatch on his face, implying that the acid attack had permanently blinded the victim in one eye.
* In 2023 Indian television series Jyoti... Umeedon Se Sajee tells about the story of an hardworking and a aspired women named, Jyoti whose life turns upside down as she is being turned into an victim of acid attack.