A record-long of human transplant organ preservation with machine perfusion of a liver for 3 days rather than usually <12 hours was reported in 2022. It could possibly be extended to 10 days and prevent substantial cell damage by low temperature preservation methods. Alternative approaches include novel cryoprotectant solvents.
There is a novel organ perfusion system under development that can restore, i.e. on the cellular level, multiple vital (pig) organs one hour after death (during which the body had a prolonged warm ischaemia), and a similar method/system for reviving (pig) brains hours after death. The system for cellular recovery could be used to preserve donor organs or for revival-treatments in medical emergencies.