The research on transgender reproduction and family planning is limited. A 2020 comparative study of children born to a transgender father and cisgender mother via donor sperm insemination in France showed no significant differences to IVF and naturally conceived children of cisgender parents.
Transgender men can experience challenges in pregnancy and birthing from the cis-normative structure within the medical system, as well as psychological challenges such as renewed gender dysphoria. The effect of continued testosterone therapy during pregnancy and breastfeeding is undetermined. Ethical concerns include reproductive rights, reproductive justice, physician autonomy, and transphobia within the health care setting.