This study is designed to: 1. Establish the value of Hepatitis B antigen in detection of potentially infectious blood donors and to define the true usefulness of screening for this factor in relation to the total problem of post-transfusion hepatitis. 2. Develop and evaluate optimal methods of testing for Hepatitis B antigen. 3. Discover other agents which may be involved in the production of post-transfusion hepatitis. 4. Investigate the role of Hepatitis B antigen in the pathogenesis of acute chronic hepatic damage. 5. Evaluate the possible interactions of this antigen with immune factors in the pathogenesis of hepatitis and other diseases.
NIH ExPorter
NIH ExPorter