We propose to continue work on the purification and the molecular and kinetic properties of human serum angiotensin converting enzyme. We will use our new fluorogenic substrate benzyloxycarbonylglycyl-tryptophanylglycine to assay the enzyme and to study its kinetic properties. We will also use other substrates. In particular we will continue work on the synthesis of chromogenic substrate that appears to be very promising.
NIH ExPorter
NIH ExPorter