OBJECTIVES: (1) The biological function and enzymatic properties of AMV p32 DNA-endonculease. (2) The precursor product relationship between RNase H species associated with murine retroviruses. (3) Identify, isolate, and characterize a reverse transcription complex in the cytoplasm of mouse embryo cells. (4) Perform a detailed analysis of the viral coded and virus-induced cell coded proteins synthesized during synchronous transformation of cells by mammalian sarcoma viruses. (5) Analysis of the integration pattern of Moloney "sarc" in normal and transformed murine cells.
NIH ExPorter
NIH ExPorter