Sam Little

Sam Little may refer to:

 Sam Little, British former clairvoyant and distributor of Miracle Mineral Solution in Uganda
 Sam Little (politician) (born 1950), member of the Louisiana House of Representatives
 Sam Little (basketball) (born 1946), American basketball player 
 Sam Little (golfer) (born 1975), English golfer
 Samuel Little (born 1940) convicted American serial killer