L 77/8 Official Journal of the European Communities 23.3.1999 COMMISSION DIRECTIVE 1999/11/EC of 8 March 1999 adapting to technical progress the principles of good laboratory practice as specified in Council Directive 87/18/EEC on the harmonisation of laws, regula- tions and administrative provisions relating to the application of the principles of good laboratory practice and the verification of their applications for tests on chemical substances (Text with EEA relevance) THE COMMISSION OF THE EUROPEAN COMMUNITIES, Having regard to the Treaty establishing the European Community, Having regard to Council Directive 87/18/EEC of 18 December 1986 on the harmonisation of laws, regulations and administrative provisions relating to the application of the principles of good laboratory practice and the verification of their applications for tests on chemical substances ('), and in particular Article 4 thereof, Whereas the principles of good laboratory practice (GLP) referred to in Directive 87/18/EEC have been modified by OECD Council Decision [C(97)186(Final)]; Whereas it is necessary to adapt the reference to the principles of GLP as specified in Directive 87/18/EEC so as to take account of these modifications, and, by publishing the full text of the revised principles of GLP, to facilitate the uniform interpretation and application thereof; Whereas the measures provided for in this Directive are in accordance with the opinion of the Committee for the adaptation to technical progress of the Directives concerning the elimination of technical barriers to trade in dangerous substances and preparations, HAS ADOPTED THIS DIRECTIVE: Article 1 Article 1(1) of Directive 87/18/EEC is replaced by the following: () OJ L 15, 17. 1. 1987, p. 29. ‘1. Member States shall take all measures necessary to ensure that laboratories carrying out tests on chem- ical products, in accordance with Directive 67/ 548/EEC, comply with the principles of good labora- tory practice as laid down in the Annex to this Directive.’ Article 2 The Annex hereto is added as Annex to Directive 87/ 18/EEC. Article 3 1. Member States shall adopt the laws, regulations and administrative provisions necessary in order to comply with this Directive not later than 30 September 1999 and shall forthwith inform the Commission thereof. 2. When Member States adopt these provisions, these shall contain a reference to this Directive or shall be accompanied by such reference at the time of their offi- cial publication. The procedure for such a reference shall be adopted by Member States. Article 4 This Directive is addressed to the Member States. Done at Brussels, 8 March 1999. For the Commission Martin BANGEMANN Member of the Commission