12.10.2005 Official Journal of the European Union L 26719 COMMISSION REGULATION (EC) No 1662/2005 of 11 October 2005 amending Annex I of Council Regulation (EC) No 953/2003 to avoid trade diversion into the European Union of certain key medicines THE COMMISSION OF THE EUROPEAN COMMUNITIES, Having regard to the Treaty establishing the European Community, Having regard to Council Regulation (EC) No 953/2003 of 26 May 2003 to avoid trade diversion into the European Union of certain key medicines ('), and in particular Article 4(4) and (8) thereof, Whereas: (1) The Commission has received modified applications under Article 4 of Regulation (EC) No 953/2003 with respect to Epivir 150 mg x 60 and Combivir 300/150 mg x 60. (20 The Commission has determined that the applications received fulfil the requirements set out in Regulation (EC) No 953/2003 in accordance with the procedure laid down in Article 5(2) of that Regulation. (3)  The applicants have been informed of the Commission decision to accept their applications. (4) It is therefore necessary to replace Annex I to Regulation (EC) No 953/2003, HAS ADOPTED THIS REGULATION: Article 1 Annex I to Regulation (EC) No 953/2003 is replaced by the Annex to this Regulation. Article 2 This regulation enters into force on the day following its publi- cation in the Official Journal of the European Union. It shall be binding in its entirety and directly applicable in all Member States. Done at Brussels, 11 October 2005. (*) OJ L 135, 3.6.2003, p. 5. Regulation as amended by Commission Regulation (EC) No 1876/2004 (O] L 326, 29.10.2004, p. 22). For the Commission Peter MANDELSON Member of the Commission