sotorasib
amgen
['specta', 'sclc', 'nsclc']
scarlet: carbo-pem-soto in nonsq 1st line kras g12g+ nsclc ph2. n=30. high orr=89%. spectacular waterfall. bicr pfs 5.7mo. os immature. any grade alt rise low, 17%
q is role in 1st line subsets unlikely to get io benefit eg pdl1low/stk11/keap1 loss. #asco23 
Thoracic Oncologist @royalmarsdenNHS, Professor @ICR_London; Chair @BTOGorg; views are my own.