rusfertide
protagonist therapeutics
['#mpn', 'rusfertide', 'mpnsm']
#asco22 #mpnsm hoffman: rusfertide for phlebotomy-dependent pv. pv is uniquely assoc w suppr of hepcidin. rusferide = hepcidin mimetic meant to further trap iron in macrophages &amp; tissues (by ferroportin degradation) to retard erythropoiesis. this study sought to achieve hct&lt;45. 
Assoc Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, MRD, post-HCT relapse, GVHD, & immune recon. Photos: pyknosis (IG)