axicabtagene ciloleucel
gilead,daiichi sankyo
['great work', 'axi-cel', 'lymsm', 'dlbcl']
sworder: cfdna, 138 axi-cel rxed pts, tumour derived &amp; car-t derived
- pre-rx &amp; 2.5 log fold reduc at wk 4 highly prognostic
- mutns in several genes assoc with relapse: pax5, cd19, tp53
- 9p24 copy gain can also emerge
- irf8 &amp; tmem30a mut also seen
great work #ash22 #lymsm 
Associate Professor of Haematology and lymphoma specialist at Oxford Cancer and Haematology centre. Christian, husband and father.