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['profound', 'pancreatic']
perhaps among the numerous reasons (profoundly immune suppressive tumor microenvironment also being key), here s a cell autonomous reason for the lack of efficacy of off the shelf immunotherapy in #pancreaticcancer. &gt;90% of cases are in lowest category of tmb. #asco23 
Pancreatic cancer researcher and GI pathologist. Striving to improve the lives of patients with cancer. Tweets are from Earth unless otherwise specified.