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the incidence of maces at 8 years is low in as patients treated with nsaids. study of 22929 patients, nsaids (shr: 0.40 [0.32-0.49], p&lt;0.001) and anti-tnfs (shr: 0.61 [0.47-0.81], p&lt;0.001) associated with a lower risk of mace, fakih o, abst#pos0301, #eular2023 
MD PhD Consultant Rheumatologist &Physician,Assoc Medical Director,Digital Health,NASS Trustee, Best Rheum Care,Visiting Fellow Henley Business School,ExecCoach