enzalutamide,olaparib,talazoparib
astellas,merck,pfizer,astrazeneca
['talapro,2', 'prostate', 'talazo', 'enzalu', 'crpc', 'enzalutamide', 'olaparib']
dr. fizazi provides data from the cohort 2 of talaprop 2 trial of enzalutamide +/- talazoparib in 1st line #mcrpc #prostatecancer #asco23 -pfs difference, w/mutation breakdown provided
-os benefit, but only 18 pts in control had olaparib subsequently
-2x increase in gd 3/4 tox 
Clinical researcher focused on #ProstateCancer, early recurrence (#BCR)  & #immunotherapy. Views are my own & do not represent the National Cancer Institute