axicabtagene ciloleucel,tisagenlecleucel
novartis,gilead
['tisa-cel', 'axi-cel', 'pcnsl']
#car-t in #pcnsl loc network.
n=25 3rd(+)line rx
tisa-cel n=16; axi-cel n=9
med age 68y
20% ecog ps 3-4 24/25 bridging rx pre car-t cr/pr 13/25
post car-t:
orr 80% cr 56%
cr 78% axi-cel vs 44% tisa-cel
med pfs 7mths
pfs 41% 1yr (plateau)
gr 3/4 crs 2/25: icans 6/25
#eha2023 
#Lymphoma #CLL specialist @UCLH. Hon Associate Professor UCL. Chair UK T cell lymphoma working group. Past chair UK CNSL study group. views my own. #WiL #lymsm