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['mmsm']
spatial heterogeneity between blind biopsies of bone marrow vs focal lesions. high-risk mutations persisted and developed within focal lesions, from diagnosis to end of therapy. suggestion that focal lesion may act as sanctuary sites for relapse &amp; clonal evolution #ash22 #mmsm 
Professor of Medicine, Chief of Myeloma Division & Experimental Therapeutics Program. Sylvester Comprehensive Cancer Center, University of Miami. Tweets = mine