abiraterone,olaparib
astrazeneca,merck
['abira', 'crpc', '#gu,(-#gui),(-#gunagratinib),(-#guard),(-#gut)', 'olaparib', 'abiraterone']
noel clark #gu23 presents data on adding olaparib to abiraterone for first line crpc. quite different benefit profile appears to be the case for those with and without ddr mutations. 
Prostate cancer medical oncologist and physician-scientist, Kendrick Family Chair for Prostate Cancer Research, Cleveland Clinic. Posts are my own.