talazoparib,enzalutamide
pfizer,astellas
['crpc', '#gu,(-#gui),(-#gunagratinib),(-#guard),(-#gut)', 'talapro2']
thoughtful discussion by on the amazing presentations by on the role of parpi in mcrpc. the degree of benefit was higher in hrrdef in talapro2 but non-hrrdef also had rpfs benefit (in pts without prior novel anti-androgen) #gu23 
Oncologist, Professor, clinical/translational research, Genitourinary Cancers, bladder, prostate, testis, Univ of Washington, Fred Hutch; views are mine