olaparib,abiraterone
astrazeneca,merck
['propel', 'olaparib', 'crpc']
comrade: ph 1/2 olaparib + radium-223 for mcrpc eligibility: any prior tx, 2+ bone mets; no visceral mets or ln&gt;4 cm) ph1 (n=12): olaparib dose 200mg bid (propel: 300mg) ph1 early outcomes: 6 mo rpfs=58%, 12 mo os=56% ph2 pending. target n=133 pts #asco23 
MD, MSc | @UofTUrology @SUO_YUO Fellow & @IHPMEUofT CEHCR PhD| Previously: @MCG_Urology and @AUB_Lebanon 🇱🇧