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['breast', 'increase,(-increased)']
 very interesting the discussion of : are 3 years enough? perhaps we will have to prolong as for adjuvant hormonal treatment in breast cancer. the only problem will be the toxicity that is not reported (financial toxicity) which increase with time of treatment. 
MD/PhD. Medical Oncologist focused in Thoracic tumors. Researcher. Assistant Professor. All opinions my own.