Ibrutinib,Tisagenlecleucel
Janssen,Abbvie,Novartis
['tisagenlecleucel', ' ibru', 'fil,veral,12', 'cyclophosphamide', 'adaptive ']
ibrutinib + tisagen in r/r mcl. minson et al
- ?ibr improves t-cell fitness
- 20 pts, med 66y, med prior 2 (mix of btk exp,naive)
- orr 90%, crr 80%, even p53 mut pts
- est 12mo pfs 75%, no deaths
- crs 75%, only 1 g2 icans
clearly v active. not sure what the ibr adds. #ash22 
Associate Professor of Haematology and lymphoma specialist at Oxford Cancer and Haematology centre. Christian, husband and father.