methotrexate,anakinra
sobi
['multiple sclerosis', 'methotrexate', 'anakinra', 'rheumatoid,arthritis', 'y biologics']
the risk of demyelination with tnfi is low but real. slight increase of risk was found in male ra patients. the small number of events is reassuring. careful consideration is recommended in individuals at highest risk of demyelinating diseases abst#op0135 #eular2023 
MD PhD Consultant Rheumatologist &Physician,Assoc Medical Director,Digital Health,NASS Trustee, Best Rheum Care,Visiting Fellow Henley Business School,ExecCoach