sotorasib,docetaxel,adagrasib,pembrolizumab
amgen,sanofi,mirati,merck,boehringer ingelheim,eli lilly
['nsclc', 'sclc', 'adagrasib', 'docetaxel', 'pembro', 'sotorasib']
 adagrasib/pembro doesn't show same pattern of hepatotoxicity w/sotorasib. but orr in kras mut+ nsclc w/chemo-pembro is &gt;60%. imo, hard to envision adagrasib/pembro eclipsing chemoio. in 2l, adagrasib isn't way better than sotorasib, which couldn't even beat docetaxel for os.
Med Onc,@CityofHope; VP Netwk Strategy AccessHope, Founder,@CancerGRACE; Web Ed,@JAMAOnc; Author/Ed, @UptoDate

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