guselkumab,risankizumab
janssen,abbvie
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gus (compared to ris) uniquely binds both cd64+ myeloid cells and il-23. cd64+ mononuclear phagocytes are enriched in the psoriatic skin and serve as the dominant il-23 source. does this lead to a change in clinical response? abs 1487 #acr22 
Passionately curious rheumatologist, world traveler, wife, mother, sister, daughter, friend, dog lover. Believer in scientific method & evidence based medicine.