capivasertib,AZD5363
astrazeneca,otsuka
['bcsm', 'sequence']
akt inhibition + et improves pfs and os after progression on et. safety profile manageable with increased diarrhea and g1-2 rash. another option before switching to chemotherapy? how to sequence with incoming cdk7i and oral serds? #faktion #bcsm #asco22 
Hematology/Oncology fellow @EinsteinMed @MontefioreNYC via @slusom and @USJLiban. Interested in EBM & clinical reasoning. Views are my own.