ibrutinib,zanubrutinib
abbvie,beigene,janssen
['lymsm', 'zanubrutinib', 'cll', 'zanu ', ' ibru', 'alpine']
alpine rct of zanu vs ibr in r/r cll. more discontinuation in ibr arm (mostly due to aes). most ighv unmut, 22% tp53mut, 45% bulky. superior pfs (including in tp53mut; look at that curve!). no os difference. fewer all-grade &amp; fatal cardiac events with zanu. new soc! #ash22 #lymsm 
#lymsm & #mmsm hematologist & patient-reported outcomes researcher @CUHematology. Founder of https://t.co/kN6qeGXfg5, @inTrainingDoc & @inHouseMag. ??????