palbociclib,abemaciclib,letrozole
eli lilly,pfizer
['paloma2', 'palbociclib', 'monarch']
#paloma2 #asco22 first os analysis of first line palbociclib for metastatic disease. no benefit in itt, but appears benefit in endocrine sensitive, when the 22% of patients with &lt;12m dfi were excluded. these pts were already mostly excluded from monaleesa trials. await monarch 
Medical Oncologist, clinician researcher. Views are my own.