bgb-11417,zanubrutinib
beigene
['zanubrutinib', 'bgb-11417', 'zanu ', 'cll']
ven no longer the lone wolf... #ash22 #cll
p1 trial novel bcl2i bgb-11417+/-zanu for rr/tn cll
more potent than ven, active against g101v (in vitro)
n=79, 8 mono 71 combo
1 dlt, g 3 aes 28% of combo arm, mostly haem
clearly v active, crs &amp; umrd seen, but fu short 
Doc from Melbourne, Australia. Treats patients with blood cancers and researches new therapies. Loves family, immersive theatre and running.