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['leusm']
#eha22 #leusm yang: most drugs used in all are relatively old! (6mp approved in 1953) 6mp/6tg show wide variability in tolerability, both count suppression and hepatotoxicity. gwas show variants in thiopurine metab (tpmt and nudt15) affect tolerance of therapy. 
Assoc Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, MRD, post-HCT relapse, GVHD, & immune recon. Photos: pyknosis (IG)