obecabtagene autoleucel
autolus
['leusm', 'felix', 'affinit']
#asco23 #leusm roddie: felix study of auto1 (obe-cel) car-t for rr b-all. unique fast-off construct (low-affinity for cd19) to reduce tox. also unique study design w split dosing based on dz burden (10m if blasts &gt;20%, 100m if &lt;20% w additional dose to 410m) 94% got full dose 
Assoc Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, MRD, post-HCT relapse, GVHD, & immune recon. Photos: pyknosis (IG)