colchicine,canakinumab
novartis
['colchicine', 'canakinumab']
#acr22 fmf
-renal amyloid dec in frequency but still important complication
-mutation mefv---pyrin protein
-not all pt have mutations
-bacterial toxin activate pyrin inflammasome
pyrin mutations assoc with resistance to yersinia pestis
-rx: colchicine daily; canakinumab
Doctor, wife, mother. avid #CLE fan. Working at doing it all and keeping sane! tweet primarily rheum and primary care issues of interest. opinions are mine