methotrexate
not tagged
['dlbcl', 'lymsm']
#lymsm #eha23 a rct in cns prophylaxis in dlbcl!
yahng et al.
iv vs it mtx in ~50% cns-ipi 4-6.
ep: cns relapse at 2yr
5.3% cns relapse, no difference btw groups
no definitive conclusion for pts with high cns-ipi, only 3 events per group. longer time to relapse for hdmtx. 