Pegloticase
Horizon Therapeutics
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mirror rct: pegloticase + mtx 60% response rate vs. 30% pegloticase + pbo in uncontrolled gout patients. 1/2 patients w/ resolution of &gt;= 1tophus in mtx gpe vs. &lt; 1/3 in pbo. safety profile comparable between groups. abst#0001 #acr22 
MD, PhD Institute of Infection and Immunity @UofGlasgow UK. Past Co-chair of @EULAR Synovitis Study Group. CrossFit athlete and Mountains lover. Views my own.