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['biomarker', 'crc,(-ccrcc),(-tbcrc049),(-mccrcc),(-mbcrc)']
visvanathan #aacr23 tbcrc-005 prospective biomarker trial results: high cmi (cumulative methylation) at week 4 is assoc'd with worse pfs (3-4 mos in metastatic setting). high cmi = progressive disease, low cmi partial/complete response
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