docetaxel,sotorasib
amgen
['biomarker', 'codebreak200']
. presents codebreak200 biomarkers. 20% keap1 &amp; stk11. lesser pfs with tp53 keap1 stk11 mutants. additional co mutations assoc with worse outcomes. notch1 coalterations assoc with soto early pd. baseline ctdna tumor burden negatively prognostic regardless of rx #asco23 
Thoracic Oncologist @royalmarsdenNHS, Professor @ICR_London; Chair @BTOGorg; views are my own.