Ziftomenib
Kura Oncology
['bet', 'venetoclax', 'ziftomenib', 'aml,(-streamline),(-seamless),(-kamloops),(-latamleaders)', 'aml,(-streamline),(-seamless),(-kamloops),(-dreamlike)', 'leukemia', 'myeloid']
another menin inhibitor with encouraging single agent phase i activity in r/r #aml with kmt2a/npm1.
interestingly, ziftomenib had more activity in npm1m aml (cr 30%) as opposed to kmt2ar.
i appreciate lack of qtc prolongation. zifto may penetrate extramedullary dz better. #ash22 
Heme-Onc Fellow @UChicago | Alumni of @OhioStateIMRes, @CCLRI | #Leukemia, #MDS, #CHIP physician-scientist. Tweets=own opinions.