177lu-psma-617,olaparib
novartis,merck,astrazeneca
['luparp', 'crpc', 'olaparib']
luparp: ph 1 lupsma+olaprib in arsi/doce treated mcrpc(n=48) no gr4+ ae or dlts 4 dose (3 hem, 1 xerostomia), 3 tx delays 5 gr3 cytopenia rp2d: 7.4gb lupsma x6 cycles + olaparib 300mg bid days -4 to 18 psa50: 66%, psa90: 44% (75%/58% in cohorts 7-9) #asco23 
MD, MSc | @UofTUrology @SUO_YUO Fellow & @IHPMEUofT CEHCR PhD| Previously: @MCG_Urology and @AUB_Lebanon 🇱🇧