Provider: Silverchair
Database: Oxford University Press
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TY  - JOUR
AU  - Liao, Yuxing
AU  - Wang, Jing
AU  - Jaehnig, Eric J
AU  - Shi, Zhiao
AU  - Zhang, Bing
T1  - WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
PY  - 2019
Y1  - 2019/05/22/
DO  - 10.1093/nar/gkz401
JO  - Nucleic Acids Research
JA  - Nucleic Acids Res
VL  - 47
IS  - W1
SP  - W199
EP  - W205
SN  - 0305-1048
AB  - WebGestalt is a popular tool for the interpretation of gene lists derived from large scale -omics studies. In the 2019 update, WebGestalt supports 12 organisms, 342 gene identifiers and 155 175 functional categories, as well as user-uploaded functional databases. To address the growing and unique need for phosphoproteomics data interpretation, we have implemented phosphosite set analysis to identify important kinases from phosphoproteomics data. We have completely redesigned result visualizations and user interfaces to improve user-friendliness and to provide multiple types of interactive and publication-ready figures. To facilitate comprehension of the enrichment results, we have implemented two methods to reduce redundancy between enriched gene sets. We introduced a web API for other applications to get data programmatically from the WebGestalt server or pass data to WebGestalt for analysis. We also wrapped the core computation into an R package called WebGestaltR for users to perform analysis locally or in third party workflows. WebGestalt can be freely accessed at http://www.webgestalt.org.
Y2  - 7/10/2020
UR  - https://doi.org/10.1093/nar/gkz401
ER  - 


