+---------+-------------------+
| aldh2   | R Documentation   |
+---------+-------------------+

ALDH2 markers and Alcoholism
----------------------------

Description
~~~~~~~~~~~

This data set contains eight ALDH2 markers and Japanese alcohlic
patients (y=1) and controls (y=0). There are genotypes for 8 loci, with
a prefix name (e.g., "EXON12") and a suffix for each of two alleles
(".a1" and ".a2").

The eight markers loci follows the following map (base pairs)

+------------+------------------+
| D12S2070   | (> 450 000),     |
+------------+------------------+
| D12S839    | (> 450 000),     |
+------------+------------------+
| D12S821    | (*~* 400 000),   |
+------------+------------------+
| D12S1344   | ( 83 853),       |
+------------+------------------+
| EXON12     | ( 0),            |
+------------+------------------+
| EXON1      | ( 37 335),       |
+------------+------------------+
| D12S2263   | ( 38 927),       |
+------------+------------------+
| D12S1341   | (> 450 000)      |
+------------+------------------+

Usage
~~~~~

::

    data(aldh2)

Format
~~~~~~

A data frame

Source
~~~~~~

Prof Ian Craig of Oxford and SGDP Centre, KCL

References
~~~~~~~~~~

Koch HG, McClay J, Loh E-W, Higuchi S, Zhao J-H, Sham P, Ball D, et al
(2000) Allele association studies with SSR and SNP markers at known
physical distances within a 1 Mb region embracing the ALDH2 locus in the
Japanese, demonstrates linkage disequilibrium extending up to 400 kb.
Hum. Mol. Genet. 9:2993-2999
