+---------+-------------------+
| crohn   | R Documentation   |
+---------+-------------------+

Crohn's disease data
--------------------

Description
~~~~~~~~~~~

The data set consist of 103 common (>5% minor allele frequency) SNPs
genotyped in 129 trios from an European-derived population. These SNPs
are in a 500-kb region on human chromosome 5q31 implicated as containing
a genetic risk factor for Crohn disease.

The positions, names and haplotype blocks reported are as follows,

::

    274044   IGR1118a_1 BLOCK 1
    274541   IGR1119a_1 *
    286593   IGR1143a_1 *
    287261   IGR1144a_1 *
    299755   IGR1169a_2 *
    324341   IGR1218a_2 *
    324379   IGR1219a_2 *
    358048   IGR1286a_1 BLOCK 1
    366811   TSC0101718
    395079   IGR1373a_1 BLOCK 2
    396353   IGR1371a_1 *
    397334   IGR1369a_2 *
    397381   IGR1369a_1 *
    398352   IGR1367a_1 BLOCK 2
    411823   IGR2008a_2
    411873   IGR2008a_1 BLOCK 3
    412456   IGR2010a_3 *
    413233   IGR2011b_1 *
    415579   IGR2016a_1 *
    417617   IGR2020a_15    *
    419845   IGR2025a_2 *
    424283   IGR2033a_1 *
    425376   IGR2036a_2 *
    425549   IGR2036a_1 BLOCK 3
    433467   IGR2052a_1 BLOCK 4
    435282   IGR2055a_1 *
    437682   IGR2060a_1 *
    438883   IGR2063b_1 *
    443565   IGR2072a_2 *
    443750   IGR2073a_1 *
    445337   IGR2076a_1 *
    447791   IGR2081a_1 *
    449895   IGR2085a_2 *
    455246   IGR2096a_1 *
    463136   IGR2111a_3 BLOCK 4
    482171   IGR2150a_1 BLOCK 5
    485828   IGR2157a_1 *
    495082   IGR2175a_2 *
    506266   IGR2198a_1 *
    506890   IGR2199a_1 BLOCK 5
    507208   IGR2200a_1 BLOCK 6
    508338   IGR2202a_1 *
    508858   IGR2203a_1 *
    510951   IGR2207a_1 *
    518478   IGR2222a_2 BLOCK 6
    519387   IGR2224a_2 BLOCK 7
    519962   IGR2225a_1 *
    520521   IGR2226a_3 *
    522600   IGR2230a_1 *
    525243   IGR2236a_1 *   
    529556   IGR2244a_4 *
    532363   IGR2250a_4 *
    545062   IGR2276a_1 *
    553189   IGR2292a_1 *
    570978   IGR3005a_1 *
    571022   IGR3005a_2 *
    576586   IGR3016a_1 *
    577141   IGR3018a_2 *
    577838   IGR3019a_2 *
    578122   IGR3020a_1 *
    579217   IGR3022a_1 *
    579529   IGR3023a_1 *
    579818   IGR3023a_3 *
    582651   IGR3029a_1 *
    582948   IGR3029a_2 *
    583131   IGR3030a_1 *
    587836   IGR3039a_1 *
    590425   IGR3044a_1 *
    590585   IGR3045a_1 *
    594115   IGR3051a_1 *
    594812   IGR3053a_1 *
    598805   IGR3061a_1 *
    601294   IGR3066a_1 *
    608759   IGR3081a_1 *
    610447   IGR3084a_1 *
    611177   IGR3086a_1 BLOCK 7
    613488   IGR3090a_1
    616241   IGR3096a_1 BLOCK 8
    616763   IGR3097a_1 *
    617299   IGR3098a_1 *
    626881   IGR3117a_1 *
    633786   IGR3131a_1 *
    635072   IGR3134a_1 *
    637441   IGR3138a_1 BLOCK 8
    648564   IGR3161a_1
    649061   IGR3162a_1 BLOCK 9
    649903   IGR3163a_1 *
    657234   IGR3178a_1 *
    662077   IGR3188a_1 *
    662819   IGR3189a_2 *
    676688   IGRX100a_1 BLOCK 9
    683387   IGR3230a_1 BLOCK 10
    686249   IGR3236a_1 *
    692320   IGR3248a_1 *
    718291   IGR3300a_2 *
    730313   IGR3324a_1 *
    731025   IGR3326a_1 *
    738461   IGR3340a_1 BLOCK 10
    871978   GENS021ex1_2   BLOCK 11
    877571   GENS020ex3_3   *
    877671   GENS020ex3_2   *
    877809   GENS020ex3_1   *
    890710   GENS020ex1_1   BLOCK 11

However it has been updated after the paper was published (posted on
`http://www.broad.mit.edu/humgen/IBD5/haplodata.html <http://www.broad.mit.edu/humgen/IBD5/haplodata.html>`_)

Usage
~~~~~

::

    data(crohn)

Format
~~~~~~

A data frame containing 387 rows and 212 columns

Source
~~~~~~

MJ Daly, JD Rioux, SF Schaffner, TJ Hudson, ES Lander (2001)
High-resolution haplotype structure in the human genome Nature Genetics
29:229-232
